DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RfC38 and Rfc3

DIOPT Version :9

Sequence 1:	NP_001285833.1	Gene:	RfC38 / 34550	FlyBaseID:	FBgn0028700	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_081285.1	Gene:	Rfc3 / 69263	MGIID:	1916513	Length:	356	Species:	Mus musculus

Alignment Length:	349	Identity:	211/349 - (60%)
Similarity:	283/349 - (81%)	Gaps:	0/349 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALWVDKYRPRELSKLDFHKDQAENLRNLCKQSDFPHLMFYGPSGAGKKTRIMCLLREMYGSGVE 65
            |:||||||||..|::||:||:||..||||.:..|||||:.||||||||||||||:|||:||.|||
Mouse     1 MSLWVDKYRPSSLARLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGIGVE 65

  Fly    66 RLRSETMTFTTPSNRKVEVMTVSSNYHLEVNPSDAGMYDRTVVIDLIKQVAQTHQIEISGQREFK 130
            :||.|..|.||||.:|:|:.|::|||||||||||||..||.|:.:::|.|||:.|:|.|.||:||
Mouse    66 KLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETSSQRDFK 130

  Fly   131 VIVISEGDELTKDAQHALRRTMEKYVATCRIIISVNSTSRIIPAIRSRCLGIRVAAPNETEIVSI 195
            |::::|.|:||||||||||||||||::|||:|:..||||::||.||||||.:||.||:..:|.|:
Mouse   131 VVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICSV 195

  Fly   196 LQNTCKREGLALPVELAKRVVDKSERNLRRALLMLEAAKVAKAPFTANQEIPDLDWQVFLRETAS 260
            |...|::||||||..||:|:.:||.||||:||||.||.:|.:.|||.:||||:.||:|:|||||:
Mouse   196 LSTVCRKEGLALPSTLARRLAEKSCRNLRKALLMCEACRVQQYPFTEDQEIPETDWEVYLRETAN 260

  Fly   261 QIISEQTPAKLEKIRERLYELLTQGVPPNLIFRGLVEQLVNNCDMSIKAKTLEFATEYEHRMQSG 325
            .|:|:|||.:|.::|.|||||||..:||.:|.:||:.:|::|||..:|.:..:.|..||||:|.|
Mouse   261 AIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLG 325

  Fly   326 AKHIFHLEAFVAQFMNIYKKFLSE 349
            :|.|:|||||||:||.:||||:.:
Mouse   326 SKAIYHLEAFVAKFMALYKKFMED 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RfC38	NP_001285833.1	rfc	3..345	CDD:234763	207/341 (61%)
Rfc3	NP_081285.1	PRK12402	3..339	CDD:237090	204/335 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837241
Domainoid	1	1.000	235	1.000	Domainoid score	I2369
eggNOG	1	0.900	-	-		E1_COG0470
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2188
Inparanoid	1	1.050	455	1.000	Inparanoid score	I1577
Isobase	1	0.950	-	0	Normalized mean entropy	S603
OMA	1	1.010	-	-		QHG53642
OrthoDB	1	1.010	-	-		D1071197at2759
OrthoFinder	1	1.000	-	-		FOG0004648
OrthoInspector	1	1.000	-	-		oto92677
orthoMCL	1	0.900	-	-		OOG6_102480
Panther	1	1.100	-	-	LDO	PTHR11669
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1091
SonicParanoid	1	1.000	-	-		X3265
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750