Protein Alignment RfC38 and RFC5

DIOPT Version :10

• Sequence 1: NP_609494.1
• Gene: RfC38 / 34550
• FlyBaseID: FBgn0028700
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_031396.1
• Gene: RFC5 / 5985
• HGNCID: 9973
• Length: 340
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 100/363 - (27%)
• Similarity: 163/363 - (44%)
• Gaps: 82/363 - (22%)

  Fly     4 WVDKYRPRELSKLDFHKDQAENLRNLCKQSDFPHLMFYGPSGAGKKTRIMCLLREMY-----GSG 63
            ||:||||:.|:.|..|:|....::....:...|||:.|||.|.||.:.|:...:::|     ||.
Human    22 WVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSM 86

  Fly    64 VERLRSETMTFTTPSNRKVEVMTVSSNYHLEVNPSDAGMYDRTVVIDLIK----QVAQTHQIEIS 124
            |                            ||:|.||    ||.  ||:|:    ..|.|..|...
Human    87 V----------------------------LELNASD----DRG--IDIIRGPILSFASTRTIFKK 117

  Fly   125 GQREFKVIVISEGDELTKDAQHALRRTMEKYVATCRIIISVNSTSRIIPAIRSRCLGIRVAAPNE 189
            |   ||::::.|.|.:|:|||:||||.:||:....|..:..|..|:||||::|||...|......
Human   118 G---FKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTP 179

  Fly   190 TEIVSILQNTCKREGLALPVELAKRVVDKSERNLRRALLMLEAAKVAKAPFT-----------AN 243
            ..:|..|::..:.|.:.:..:..|.:|..|..::||||.:|::..:|....|           ..
Human   180 ELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLK 244

  Fly   244 QEIPD-LDW---QVFLRETASQIISEQTPAKLEKIRE-RLYELLTQGVPPNLIFRGLVEQLVNNC 303
            .:|.: |||   |.|  .||.:.|:|     |:.::. .|:::||:           :...|:..
Human   245 SDIANILDWMLNQDF--TTAYRNITE-----LKTLKGLALHDILTE-----------IHLFVHRV 291

  Fly   304 DM--SIKAKTLEFATEYEHRMQSGAKHIFHLEAFVAQF 339
            |.  |::...|....:.|:|:..|......|.:.:|.|
Human   292 DFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RfC38	NP_609494.1	rfc	3..345	CDD:234763	100/363 (28%)
RFC5	NP_031396.1	rfc	16..329	CDD:234763	99/361 (27%)