Protein Alignment RfC38 and RFC2

DIOPT Version :10

• Sequence 1: NP_609494.1
• Gene: RfC38 / 34550
• FlyBaseID: FBgn0028700
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_852136.1
• Gene: RFC2 / 5982
• HGNCID: 9970
• Length: 354
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 90/347 - (25%)
• Similarity: 162/347 - (46%)
• Gaps: 53/347 - (15%)

  Fly     4 WVDKYRPRELSKLDFHKDQAENLRNLCKQSDFPHLMFYGPSGAGKKTRIMCLLREMYGSGVERLR 68
            ||:||||.:|:::..::|....|....::.:.|:::..||.|.||.|.|:||.|.:.|..::
Human    38 WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALK--- 99

  Fly    69 SETMTFTTPSNRKVEVMTVSSNYHLEVNPS-DAGMYDRTVVIDLIKQVAQTHQIEISGQREFKVI 132
                          :.|       ||:|.| |.|:   .||.:.||..||.......|:.  |:|
Human   100 --------------DAM-------LELNASNDRGI---DVVRNKIKMFAQQKVTLPKGRH--KII 138

  Fly   133 VISEGDELTKDAQHALRRTMEKYVATCRIIISVNSTSRIIPAIRSRCLGIRVAAPNETEIVSILQ 197
            ::.|.|.:|..||.|||||||.|..|.|..::.|::.:||..|:|||..:|.....:.:|::.|.
Human   139 ILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLM 203

  Fly   198 NTCKREGLALPVELAKRVVDKSERNLRRALLMLEAAKVAKAPFTA----NQE----IPDLDWQVF 254
            |..::|.:....:..:.::..::.::|:||..|::.      |:.    |.|    :.|....:.
Human   204 NVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQST------FSGFGFINSENVFKVCDEPHPLL 262

  Fly   255 LRETASQIISEQTPAKLEKIRERLYELLTQGVPPNLIFRGLVEQLVNNCDMSIKAKTLEFATE-- 317
            ::|.....::    |.:::..:.|..|...|..|..|. |.:.::.....|:...| |||..|
Human   263 VKEMIQHCVN----ANIDEAYKILAHLWHLGYSPEDII-GNIFRVCKTFQMAEYLK-LEFIKEIG 321

  Fly   318 YEH-RMQSGAKHIFHLEAFVAQ 338
            |.| ::..|...:..:...:|:
Human   322 YTHMKIAEGVNSLLQMAGLLAR 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RfC38	NP_609494.1	rfc	3..345	CDD:234763	90/347 (26%)
RFC2	NP_852136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		PLN03025	36..348	CDD:178596	90/347 (26%)