DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RfC38 and Rfc2

DIOPT Version :9

Sequence 1:	NP_001285833.1	Gene:	RfC38 / 34550	FlyBaseID:	FBgn0028700	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_064406.1	Gene:	Rfc2 / 19718	MGIID:	1341868	Length:	349	Species:	Mus musculus

Alignment Length:	352	Identity:	88/352 - (25%)
Similarity:	157/352 - (44%)	Gaps:	63/352 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WVDKYRPRELSKLDFHKDQAENLRNLCKQSDFPHLMFYGPSGAGKKTRIMCLLREMYGSGVERLR 68
            ||:||||.:|:::..::|....|....::.:.|:::..||.|.||.|.|:||.|.:.|..::
Mouse    33 WVEKYRPLKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALK--- 94

  Fly    69 SETMTFTTPSNRKVEVMTVSSNYHLEVNPS-DAGMYDRTVVIDLIKQVAQTHQIEISGQREFKVI 132
                                 :..||:|.| |.|:   .||.:.||..||.......|:.  |:|
Mouse    95 ---------------------DAVLELNASNDRGI---DVVRNKIKMFAQQKVTLPKGRH--KII 133

  Fly   133 VISEGDELTKDAQHALRRTMEKYVATCRIIISVNSTSRIIPAIRSRCLGIRVAAPNETEIVSILQ 197
            ::.|.|.:|..||.|||||||.|..|.|..::.|::.:||..|:|||..:|.....:.::::.|.
Mouse   134 ILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLTRLM 198

  Fly   198 NTCKREGLALPVELAKRVVDKSERNLRRALLMLEAA-------------KVAKAPFTANQEIPDL 249
            |..::|.:....:..:.::..::.::|:||..|::.             ||...|.      |.|
Mouse   199 NVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPH------PLL 257

  Fly   250 DWQVFLRETASQIISEQTPAKLEKIRERLYELLTQGVPPNLIFRGLVEQLVNNCDMSIKAKTLEF 314
                     ..::|.....|.:::..:.|..|...|..|..:. |.:.::.....|:...| |||
Mouse   258 ---------VKEMIQHCVDANIDEAYKILAHLWHLGYSPEDVI-GNIFRVCKTFPMAEYLK-LEF 311

  Fly   315 ATE--YEH-RMQSGAKHIFHLEAFVAQ 338
            ..|  |.| ::..|...:..:...:|:
Mouse   312 IKEIGYTHMKVAEGVNSLLQMAGLLAR 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RfC38	NP_001285833.1	rfc	3..345	CDD:234763	88/352 (25%)
Rfc2	NP_064406.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		PLN03025	31..343	CDD:178596	88/352 (25%)
		AAA	46..180	CDD:99707	49/162 (30%)
		AAA_assoc_2	203..>231	CDD:292811	4/27 (15%)
		Rep_fac_C	269..337	CDD:285713	14/69 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0470
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810