DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Csl4 and exos-1

DIOPT Version :9

Sequence 1:	NP_609492.1	Gene:	Csl4 / 34548	FlyBaseID:	FBgn0032346	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_499416.1	Gene:	exos-1 / 176532	WormBaseID:	WBGene00012966	Length:	208	Species:	Caenorhabditis elegans

Alignment Length:	209	Identity:	71/209 - (33%)
Similarity:	111/209 - (53%)	Gaps:	20/209 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ETVVCLPGERLCRTEDSIVLGIGTYEQNGYIYASKSGIVNIEDSGDK----CQVVSVHKPGFHL- 66
            ||:|. ||:::........:|.|.||.|..|:||.:|.||:....||    .||:.|.:....|
Worm     4 ETLVA-PGDKVLDAIGEYRMGKGLYEANRRIFASVAGFVNVYGFRDKSDNLVQVIEVRRSEDQLD 67

  Fly    67 --TIPATGDVVTARVLVTTPKFAKCAIFCVRNVLLESSYRGLLRKEDVRETEKDRVDIYKSF-RP 128
              .:|..|.:|||:|:....:||||.|..:.:.:.:..:..||.|:.:|..|.:..:.:|:| ||
Worm    68 NELLPFHGAIVTAKVMAVGLRFAKCDIISIGDKVYKKRFSALLPKKKLRPLEPELSEPFKNFVRP 132

  Fly   129 GDVILARVIN--QLEQSFLLTTAENELGVVIAYASDYRKTRVPMVPVGWSEMQCPQTTIKEPRKV 191
            .|.|||:|..  :::..|:|:.||:|||||:...    :...||..|.|:.:...:|...||||:
Worm   133 NDYILAKVCEDAEIKDKFVLSIAEDELGVVLCRG----RFGEPMQKVDWNTVVSTRTGKTEPRKM 193

  Fly   192 AKV-----LPESSI 200
            |||     ||..|:
Worm   194 AKVPQKCTLPTQSV 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Csl4	NP_609492.1	Csl4	10..193	CDD:224021	63/192 (33%)
		ECR1_N	10..47	CDD:291080	13/36 (36%)
		S1_CSL4	66..156	CDD:240217	33/95 (35%)
exos-1	NP_499416.1	Csl4	5..195	CDD:224021	64/194 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162631
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1096
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9359
Inparanoid	1	1.050	97	1.000	Inparanoid score	I3609
Isobase	1	0.950	-	0	Normalized mean entropy	S1914
OMA	1	1.010	-	-		QHG55393
OrthoDB	1	1.010	-	-		D1200489at2759
OrthoFinder	1	1.000	-	-		FOG0004386
OrthoInspector	1	1.000	-	-		oto18394
orthoMCL	1	0.900	-	-		OOG6_101821
Panther	1	1.100	-	-	LDO	PTHR12686
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R252
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.790