DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and CYC8

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_009670.3	Gene:	CYC8 / 852410	SGDID:	S000000316	Length:	966	Species:	Saccharomyces cerevisiae

Alignment Length:	139	Identity:	31/139 - (22%)
Similarity:	47/139 - (33%)	Gaps:	39/139 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 NKRRAEIQKEIQRETDMRERVKQFQENSVREALVVD--------VRKEAKATPKPDTL--QYPPS 171
            |...:.|.|.:...|.:.|..|  .|.|.:...||:        ..|..||...|..:  |.||.
Yeast   740 NSPNSNINKLVNTATSIEENAK--SEVSNQSPAVVESNTNNTSQEEKPVKANSIPSVIGAQEPPQ 802

  Fly   172 SGGASRLAT------PLMRPPMSSVRGSGRINVNFTTQHKRVTPKRESQAAMEKAYAAAGGPNAN 230
            ....:..||      |..:|            :|...:...|.|...|:::..|         ||
Yeast   803 EASPAEEATKAASVSPSTKP------------LNTEPESSSVQPTVSSESSTTK---------AN 846

  Fly   231 VQSPMESVD 239
            .||..|:::
Yeast   847 DQSTAETIE 855

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226
CYC8	NP_009670.3	TPR	<38..142	CDD:223533
		TPR repeat	46..74	CDD:276809
		TPR repeat	80..108	CDD:276809
		TPR	94..391	CDD:223533
		TPR repeat	113..143	CDD:276809
		TPR repeat	150..178	CDD:276809
		TPR repeat	184..211	CDD:276809
		TPR repeat	223..253	CDD:276809
		TPR repeat	258..290	CDD:276809
		TPR repeat	296..324	CDD:276809
		TPR repeat	329..359	CDD:276809
		TPR repeat	364..393	CDD:276809
		Herpes_BLLF1	<697..944	CDD:282904	31/139 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900