DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and SWA2

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_010606.1	Gene:	SWA2 / 851918	SGDID:	S000002728	Length:	668	Species:	Saccharomyces cerevisiae

Alignment Length:	229	Identity:	44/229 - (19%)
Similarity:	81/229 - (35%)	Gaps:	92/229 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EDIKISIELNRLVTRKPDVVLLPQYLKFNNPPIFFERHLAQEIDEMASFCRIFKNEAR----IVL 69
            :::| .:|:.||::..   :.:.:..:|....:.:||:|           .|.|::.:    :.:
Yeast   140 DEVK-DMEIARLMSLG---LSIEEATEFYENDVTYERYL-----------EILKSKQKERNDLAI 189

  Fly    70 VKKEKGLWPEMFQKLDKEALMQ--------------------KRL---------EIADLIVERNK 105
            .|||.|:      |::|..|..                    |:|         |..|.:...:|
Yeast   190 RKKESGI------KMEKSGLSNIVGTDSNNLFSMATDFFNKGKKLVDQWTSFPPEANDRLNNYSK 248

  Fly   106 KRDEKALERYDNKRRAEIQKEIQRETDMRERVKQFQENSVREAL----------------VVDVR 154
            ..|:  :|.||          :.:..|...|: .|::|.|.|.|                .:|:.
Yeast   249 THDK--VEDYD----------LPQVNDSPNRI-LFEDNEVVENLPPADNPDQDLLTDFETKIDIT 300

  Fly   155 KEAKATPKPD-TLQYPPSSG----GASRLATPLM 183
            |..    .|| :....|:||    ..||...||:
Yeast   301 KRT----APDVSHSSSPTSGILIEENSRRNEPLI 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	14/75 (19%)
SWA2	NP_010606.1	Ubiq-assoc	138..181	CDD:401184	10/55 (18%)
		TPR	<374..497	CDD:223533
		TPR repeat	374..402	CDD:276809
		TPR repeat	407..441	CDD:276809
		TPR repeat	467..495	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900