DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and OGT

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_858058.1	Gene:	OGT / 8473	HGNCID:	8127	Length:	1046	Species:	Homo sapiens

Alignment Length:	89	Identity:	20/89 - (22%)
Similarity:	34/89 - (38%)	Gaps:	23/89 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 TDMRERVKQFQENSVREALVVD-VRKEAKATPKP-DTLQYPPSSGGASRLA-----------TPL 182
            ||..||:|:.      .::|.| :.|....:..| .::.||.|.|....:|           ..|
Human   480 TDYDERMKKL------VSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVL 538

  Fly   183 MRPPMSSVR----GSGRINVNFTT 202
            .:||....:    ..||:.|.:.:
Human   539 HKPPYEHPKDLKLSDGRLRVGYVS 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226
OGT	NP_858058.1	TPR 1	21..54
		PEP_TPR_lipo	<22..>465	CDD:274350
		TPR repeat	24..49	CDD:276809
		TPR repeat	57..83	CDD:276809
		TPR 2	89..122
		TPR repeat	89..117	CDD:276809
		TPR repeat	122..152	CDD:276809
		TPR 3	123..156
		TPR 4	157..190
		TPR repeat	157..185	CDD:276809
		TPR 5	191..224
		TPR repeat	191..219	CDD:276809
		TPR 6	225..258
		TPR repeat	226..253	CDD:276809
		TPR 7	259..292
		TPR repeat	259..287	CDD:276809
		TPR 8	293..326
		TPR repeat	293..321	CDD:276809
		TPR 9	327..360
		TPR repeat	327..355	CDD:276809
		TPR repeat	360..390	CDD:276809
		TPR 10	361..394
		TPR 11	395..428
		TPR repeat	395..423	CDD:276809
		TPR 12	429..462
		TPR repeat	429..457	CDD:276809
		TPR 13, truncated	463..473
		Nuclear localization signal. /evidence=ECO:0000255	487..503		4/21 (19%)
		Glyco_transf_41	556..1024	CDD:372753	1/7 (14%)
		Required for phosphatidylinositol 3,4,5-triphosphate binding	991..1010
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900