DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and ODAD4

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_113609.1	Gene:	ODAD4 / 83538	HGNCID:	25280	Length:	672	Species:	Homo sapiens

Alignment Length:	178	Identity:	45/178 - (25%)
Similarity:	71/178 - (39%)	Gaps:	47/178 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QISQTEEDIKISIELNRLVTRKPDVVLLPQYLKFNNPPIFFERHLAQEIDEMASFCRIFKNEARI 67
            |.::.|.||:..:..:.||. :..|.|.......||    ||:.|     |.|..  :..|||:.
Human   425 QCAEEEGDIEWQLNASVLVA-QAQVKLRDFESAVNN----FEKAL-----ERAKL--VHNNEAQQ 477

  Fly    68 VLVK----KEKGLWPEMFQKLDKEALMQKRLEIADLIVERNKKRDEKALERYDNKRRAEIQKEIQ 128
            .::.    ..||:..|: :|.:              .||..|::.|.....|::       :.|.
Human   478 AIISALDDANKGIIREL-RKTN--------------YVENLKEKSEGEASLYED-------RIIT 520

  Fly   129 RETDMRERVKQFQENSVREALVVDVRKEAKATPKPD-----TLQYPPS 171
            ||.||| ||:...|..|::   .|..::.|.|.:.|     .||.|.|
Human   521 REKDMR-RVRDEPEKVVKQ---WDHSEDEKETDEDDEAFGEALQSPAS 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	20/80 (25%)
ODAD4	NP_113609.1	TPR 1. /evidence=ECO:0000255	13..46
		TPR_11	16..78	CDD:290150
		TPR repeat	16..41	CDD:276809
		TPR repeat	46..76	CDD:276809
		TPR 2. /evidence=ECO:0000255	48..80
		TPR_11	49..112	CDD:290150
		TPR 3. /evidence=ECO:0000255	81..114
		TPR repeat	81..109	CDD:276809
		TPR 4. /evidence=ECO:0000255	275..311
		TPR repeat	311..349	CDD:276809
		TPR_12	316..385	CDD:290160
		TPR 5. /evidence=ECO:0000255	320..353
		TPR 6. /evidence=ECO:0000255	360..393
		TPR repeat	360..385	CDD:276809
		TPR_12	361..429	CDD:290160	1/3 (33%)
		TPR 7. /evidence=ECO:0000255	397..430		1/4 (25%)
		TPR_12	398..468	CDD:290160	14/52 (27%)
		TPR repeat	431..465	CDD:276809	11/43 (26%)
		TPR 8. /evidence=ECO:0000255	437..470		11/44 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	527..672		12/41 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900