DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and Odad4

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_083194.2	Gene:	Odad4 / 74407	MGIID:	1921657	Length:	624	Species:	Mus musculus

Alignment Length:	250	Identity:	59/250 - (23%)
Similarity:	93/250 - (37%)	Gaps:	60/250 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QISQTEEDIKISIELNRLVTRKPDVVLLPQYLKFNNPPIFFERHLAQEIDEMASFCRIFKNEARI 67
            |.::.|.|::..:..:.||. :..|.|.......||    ||:.|     |.|..  :..|||:.
Mouse   423 QYAEEEGDLEWQLNASVLVA-QAQVKLRDFESAVNN----FEKAL-----ERAKL--VHNNEAQQ 475

  Fly    68 VLVK----KEKGLWPEMFQKLDKEALMQKRLEIADLIVERNKKRDEKALERYDNKRRAEIQ---- 124
            .::.    ..||:..|:.:...:|.|.:|                   .||.|...:.::|
Mouse   476 AIISALDDANKGIIEELKKTNYREILREK-------------------AERQDIMSQMDLQGASE 521

  Fly   125 KEIQRETDMRER-VKQFQENSVREALVVDVRKEAKATPKPDTLQYPPSSGGASRLATPLMRPPMS 188
            ||..|..:.:|| |||::.         |...|.:||   |..|...||||.|:   .|:....|
Mouse   522 KEPLRGREEQERVVKQWER---------DQESEREAT---DDEQDRKSSGGLSK---KLLGDGHS 571

  Fly   189 S---VRGSGRINVNFTTQHKRVTPKRESQAAMEKAYAAAGGPNANVQSPMESVDE 240
            |   :|...|......:.:....|..:.....||..|.|.  ...||...::.:|
Mouse   572 SNLGIRRESREIYRRLSDYSSHLPSEDGSQKQEKKQAEAA--KGEVQKLEKTKEE 624

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	19/80 (24%)
Odad4	NP_083194.2	TPR 1. /evidence=ECO:0000255	11..44
		TPR_11	14..76	CDD:290150
		TPR repeat	14..39	CDD:276809
		TPR repeat	44..74	CDD:276809
		TPR 2. /evidence=ECO:0000255	46..78
		TPR_11	47..110	CDD:290150
		TPR 3. /evidence=ECO:0000255	79..112
		TPR repeat	79..107	CDD:276809
		TPR 4. /evidence=ECO:0000255	273..309
		TPR repeat	309..347	CDD:276809
		TPR_12	314..383	CDD:290160
		TPR 5. /evidence=ECO:0000255	318..351
		TPR 6. /evidence=ECO:0000255	358..391
		TPR repeat	358..383	CDD:276809
		TPR_12	359..427	CDD:290160	1/3 (33%)
		TPR 7. /evidence=ECO:0000255	395..428		1/4 (25%)
		TPR_12	396..466	CDD:290160	13/52 (25%)
		TPR repeat	429..463	CDD:276809	10/43 (23%)
		TPR 8. /evidence=ECO:0000255	435..468		11/44 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	511..624		32/129 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900