DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14921 and kdm6a

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_005167851.1	Gene:	kdm6a / 569277	ZFINID:	ZDB-GENE-081105-56	Length:	1452	Species:	Danio rerio

Alignment Length:	180	Identity:	40/180 - (22%)
Similarity:	65/180 - (36%)	Gaps:	20/180 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PDVVLLPQYLKFN--NPPIFFERHLAQEIDEMASFCRIFKNEARIVLVKKEKGLWPEMFQKLDKE 87
            |.:..||:. |.|  .|.|:.|.........:..||....|...::     :||...:  |||..
Zfish   977 PPIPPLPKD-KLNPPTPSIYLENKRDAFFPPLHQFCTNTANPVTVI-----RGLAGAL--KLDLG 1033

  Fly    88 ALMQKRLEIA--DLIVERNKKRDEKALERYD-NKRRAEIQKEIQRETDMRERVKQFQENSVREAL 149
            ....|.|..|  :.:||...:..:...|.:| ...|...:.|..|......|..|:|.:|.:|:|
Zfish  1034 LFSTKTLVEANPEHLVEVRTQLSQPTDENWDVTGSRKMWRCESSRSHTTIARYAQYQASSFQESL 1098

  Fly   150 VVDVRKEAKATPKPDTLQYPPSSGGASRLATPLMRPPMSSVRGSGRINVN 199
            ..:  .|.|........:..||.....|     .|.|...::....|:::
Zfish  1099 REE--NEKKGQKDHSDTESAPSENVVRR-----RRGPFKHIKFGTNIDLS 1141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	13/57 (23%)
kdm6a	XP_005167851.1	TPR	74..332	CDD:223533
		TPR repeat	95..123	CDD:276809
		TPR repeat	131..176	CDD:276809
		TPR repeat	181..211	CDD:276809
		TPR repeat	222..250	CDD:276809
		TPR repeat	260..295	CDD:276809
		TPR_17	289..320	CDD:290167
		TPR_11	302..365	CDD:290150
		TPR repeat	302..329	CDD:276809
		TPR repeat	334..364	CDD:276809
		TPR_1	335..368	CDD:278916
		TPR repeat	369..395	CDD:276809
		SSDP	572..852	CDD:282372
		JmjC	1149..1213	CDD:214721
		JmjC	1183..1291	CDD:202224
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900