DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and kdm6al

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_005168853.1	Gene:	kdm6al / 569207	ZFINID:	ZDB-GENE-070112-2002	Length:	1356	Species:	Danio rerio

Alignment Length:	170	Identity:	35/170 - (20%)
Similarity:	68/170 - (40%)	Gaps:	44/170 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 TEEDIKISI---ELNRLVTRKPDVVLLPQYLKFNNPPIFFERHLA---QEIDEMASFC--RIFKN 63
            |....|:::   |.|:|.:.|..|.::  :|.:|     ..|::.   |.:.||..||  |..:.
Zfish  1199 TAHQYKLAVERYEWNKLQSVKSMVPMV--HLSWN-----MARNIKVADQRLFEMIKFCLLRTLRQ 1256

  Fly    64 EARIVLVKKEKGLWPEMFQKLDKEALMQKR-------------LEIADLIV---ERNKKRDEKAL 112
            ...|          .|......||.|.|:|             :|:.:|:.   |.:..|...|:
Zfish  1257 TQSI----------RESLLSAGKETLWQRRSRDEPAHYCSVCEVEVWNLLFVCSEGSPCRPAAAV 1311

  Fly   113 ERYDNKRRAEIQKE---IQRETDMRERVKQFQENSVREAL 149
            :..|..|:|.:..:   :.::..|.:..:.:::.|:..||
Zfish  1312 QCQDCARKASVDLQGFVVLQQFRMEDLTQLYEQFSLAPAL 1351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	18/81 (22%)
kdm6al	XP_005168853.1	TPR_11	92..161	CDD:290150
		TPR repeat	93..121	CDD:276809
		TPR_11	129..194	CDD:290150
		TPR repeat	129..159	CDD:276809
		TPR_1	130..163	CDD:278916
		TPR repeat	164..194	CDD:276809
		TPR repeat	205..233	CDD:276809
		TPR repeat	243..278	CDD:276809
		TPR_17	272..303	CDD:290167
		TPR_11	285..348	CDD:290150
		TPR repeat	285..312	CDD:276809
		TPR repeat	317..347	CDD:276809
		TPR_1	318..351	CDD:278916
		TPR repeat	352..378	CDD:276809
		JmjC	1053..1117	CDD:214721
		JmjC	1087..1195	CDD:202224
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900