DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and ifit10

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001287801.1	Gene:	ifit10 / 567441	ZFINID:	ZDB-GENE-121214-248	Length:	482	Species:	Danio rerio

Alignment Length:	183	Identity:	39/183 - (21%)
Similarity:	65/183 - (35%)	Gaps:	71/183 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVQISQTEEDIKISIELNRLVTRKPD-----VVL---LPQYLKFNNPPIFFERHLAQEIDE---M 54
            :::.|.|.:.::::||:|      ||     |:|   |..|.::.....:.|:.|.:..|.   |
Zfish   197 VLEDSATVKQLRLAIEMN------PDDDVLKVLLSLRLIVYKRYGEAESWVEKALEKSPDHPHVM 255

  Fly    55 ASFCRIFKNEARIVLVKKEKGLWPEMFQKLDKEALMQKRLEIADLIVERNKKRDEKALERYDNKR 119
            ....:.|:|          ||                        .|:|:....::||||..|..
Zfish   256 RYVGKFFRN----------KG------------------------CVDRSIDLLKRALERSPNSS 286

  Fly   120 RAEIQ-------KEIQRETDMRERVKQFQENSVREALVVDVRKEA-----KAT 160
            ....|       |:||        |.|.|.:..|.:.|..:|.:.     |||
Zfish   287 FIHHQLALCYKYKKIQ--------VLQEQSHHARGSRVQQLRDQCIFHLEKAT 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	19/87 (22%)
ifit10	NP_001287801.1	TPR repeat	58..86	CDD:276809
		TPR repeat	91..130	CDD:276809
		TPR repeat	142..172	CDD:276809
		TPR repeat	177..213	CDD:276809	3/15 (20%)
		TPR repeat	251..281	CDD:276809	9/63 (14%)
		TPR repeat	338..362	CDD:276809
		TPR repeat	375..406	CDD:276809
		TPR repeat	411..463	CDD:276809
		TPR_1	436..468	CDD:278916
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900