DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and Tmtc1

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_945318.2	Gene:	Tmtc1 / 387314	MGIID:	3039590	Length:	942	Species:	Mus musculus

Alignment Length:	89	Identity:	23/89 - (25%)
Similarity:	38/89 - (42%)	Gaps:	16/89 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 LEIADLIVERNKKRDE--KALERYDNKRRAEIQKEIQRETDMRERVKQF---QENSVREALVVD- 152
            ||...|:...:.|::.  ||||        .|:|.:|.:....:.:.:.   :.|.:||..::|
Mouse   811 LECYRLLSAIHSKQEHHGKALE--------AIEKALQLKPKDPKVISELFFTKGNQLREQNLLDK 867

  Fly   153 --VRKEAKATPKPDTLQYPPSSGG 174
              ...||..|..||..|...:.||
Mouse   868 AFESYEAAVTLDPDQAQAWMNMGG 891

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226
Tmtc1	NP_945318.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	245..285
		DUF1736	351..425	CDD:285594
		TPR_11	542..605	CDD:290150
		TPR 1	543..576
		TPR_2	543..576	CDD:285020
		TPR repeat	543..571	CDD:276809
		TPR repeat	576..603	CDD:276809
		TPR 2	577..607
		TPR	577..607	CDD:197478
		TPR_17	596..628	CDD:290167
		TPR 3	608..641
		TPR repeat	608..636	CDD:276809
		TPR	621..940	CDD:223533	23/89 (26%)
		TPR 4	642..675
		TPR repeat	642..670	CDD:276809
		TPR repeat	675..705	CDD:276809
		TPR 5	676..709
		TPR 6	710..742
		TPR repeat	710..738	CDD:276809
		TPR_7	715..744	CDD:289919
		TPR 7	743..776
		TPR repeat	743..771	CDD:276809
		TPR_14	749..786	CDD:290164
		TPR repeat	776..806	CDD:276809
		TPR 8	811..844		11/40 (28%)
		TPR repeat	812..839	CDD:276809	9/34 (26%)
		TPR repeat	844..878	CDD:276809	6/33 (18%)
		TPR 9	849..882		8/32 (25%)
		TPR 10	883..916		3/9 (33%)
		TPR_1	883..915	CDD:278916	3/9 (33%)
		TPR repeat	883..911	CDD:276809	3/9 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900