DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and Spag1

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001012116.1	Gene:	Spag1 / 315033	RGDID:	1310702	Length:	893	Species:	Rattus norvegicus

Alignment Length:	176	Identity:	41/176 - (23%)
Similarity:	71/176 - (40%)	Gaps:	18/176 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 EMFQKLDKEA-LMQKRLEIADLIVERNK--KRDEKALERYDNKRRAEIQ----KEIQRETDMRER 136
            :|||.|.:|. .:.|.....|.|.:.|:  |.:.||...|.|:....::    :|.:.:.|   :
  Rat   603 KMFQALKEEGNQLVKDKNYKDAISKYNECLKINSKACAIYTNRALCYLKLGQFEEAKLDCD---K 664

  Fly   137 VKQFQENSVREALVVDVR-------KEAKATPKPDTLQYPPSSGGASRLATPLMRPPMSSVRGSG 194
            ..|....:|:.:..:::.       :|..|.|....|..|.||..|..|.|.....|.|..|...
  Rat   665 ALQIDSKNVKASYRLELAQKGLENCRERVADPSQVVLLSPDSSEAARHLDTKNDTAPPSRERERR 729

  Fly   195 RINVNFTTQHKRVTPKRESQA-AMEKAYAAAGGPNANVQSPMESVD 239
            ||.:..........|:|.::| |:|:.::|.......|..|..:.:
  Rat   730 RIEIQEVDDSSDEEPERPAEASAVEEGWSAERAGKIEVCKPRNAYE 775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	0/1 (0%)
Spag1	NP_001012116.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..155
		3a0801s09	141..>303	CDD:273380
		TPR 1	213..246
		TPR repeat	217..241	CDD:276809
		TPR repeat	246..275	CDD:276809
		TPR 2	247..279
		TPR 3	280..313
		TPR repeat	280..308	CDD:276809
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..344
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	349..368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	373..437
		TPR 4	429..463
		3a0801s09	<432..>569	CDD:273380
		TPR repeat	432..458	CDD:276809
		TPR repeat	466..500	CDD:276809
		TPR 5	471..504
		TPR repeat	505..533	CDD:276809
		TPR 6	506..538
		3a0801s09	569..>695	CDD:273380	19/94 (20%)
		TPR 7	605..638		9/32 (28%)
		TPR repeat	606..633	CDD:276809	7/26 (27%)
		TPR repeat	638..668	CDD:276809	5/32 (16%)
		TPR 8	639..672		5/35 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..756		16/51 (31%)
		RPAP3_C	769..858	CDD:404718	1/7 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810