DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and Tomm34

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001037709.1	Gene:	Tomm34 / 311621	RGDID:	1309029	Length:	309	Species:	Rattus norvegicus

Alignment Length:	136	Identity:	30/136 - (22%)
Similarity:	53/136 - (38%)	Gaps:	45/136 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 RIFKNEARIVLVKKEKGLWPEMFQKLDKEALMQKRLE--------IADLIVERNKKRDEKALE-- 113
            |:.|.|.. .|||  ||...:..:|. .|:|:...||        :..|::::.|:.::...|
  Rat   194 RVLKEEGN-ELVK--KGNHKKAIEKY-SESLLFSSLESATYSNRALCHLVLKQYKEAEKDCTEAL 254

  Fly   114 RYDNK------RRAEIQKEIQRETDMRERVKQFQENSVREALVVDVRKEAKATPKPDTLQYPPSS 172
            :.|.|      |||:..|.:          |.::.:      :.|:         ...||..|.:
  Rat   255 KLDGKNVKAFYRRAQAYKAL----------KDYKSS------LADI---------SSLLQIEPRN 294

  Fly   173 GGASRL 178
            |.|.:|
  Rat   295 GPAHKL 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	8/21 (38%)
Tomm34	NP_001037709.1	TPR repeat	261..289	CDD:276809	6/52 (12%)
		TPR 6	262..294		9/56 (16%)
		TPR 1	9..42
		TPR repeat	9..37	CDD:276809
		3a0801s09	<11..>294	CDD:273380	27/128 (21%)
		TPR repeat	50..80	CDD:276809
		TPR 2	51..84
		TPR repeat	85..113	CDD:276809
		TPR 3	86..118
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	158..187
		TPR 4	193..226		11/35 (31%)
		TPR repeat	193..221	CDD:276809	10/30 (33%)
		TPR repeat	226..256	CDD:276809	4/29 (14%)
		TPR 5	227..260		4/32 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900