DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and Tmtc4

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_006252585.1	Gene:	Tmtc4 / 290501	RGDID:	1560183	Length:	773	Species:	Rattus norvegicus

Alignment Length:	80	Identity:	18/80 - (22%)
Similarity:	31/80 - (38%)	Gaps:	30/80 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 FCRIFKNEAR-------------------IVLVKKEKGL----WPEMFQKLDKEALMQKRLEIAD 98
            :||.||....                   :.::.||:|:    ...:|     :.|:..||:|
  Rat   219 YCRAFKETGNKEGTHSSTFWVLLSIFLGAVAMLCKEQGVTVLGLNAVF-----DILVIGRLDI-- 276

  Fly    99 LIVERNKKRDEKALE 113
            |:..|...|.:|:||
  Rat   277 LVAVRKVLRKDKSLE 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	7/46 (15%)
Tmtc4	XP_006252585.1	DUF1736	324..398	CDD:285594
		TPR	513..771	CDD:223533
		TPR_1	514..547	CDD:278916
		TPR repeat	514..542	CDD:276809
		TPR_17	536..569	CDD:290167
		TPR repeat	547..577	CDD:276809
		TPR_1	582..615	CDD:278916
		TPR repeat	582..610	CDD:276809
		TPR repeat	616..642	CDD:276809
		TPR repeat	650..678	CDD:276809
		TPR repeat	683..713	CDD:276809
		TPR_17	706..739	CDD:290167
		TPR repeat	718..746	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900