DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14921 and Tmtc3

DIOPT Version :9

Sequence 1:NP_609491.1 Gene:CG14921 / 34547 FlyBaseID:FBgn0032345 Length:240 Species:Drosophila melanogaster
Sequence 2:NP_001103483.1 Gene:Tmtc3 / 237500 MGIID:3036255 Length:920 Species:Mus musculus


Alignment Length:287 Identity:58/287 - (20%)
Similarity:96/287 - (33%) Gaps:90/287 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 LKFNNPPIFFERHL-AQEIDEMASFCRIFKNEARIVLVKKEKGLWPEMFQK------------LD 85
            ||.|.|....|.:| |.|:|.  :...::.|.|.:.:..||.....:.|.:            .:
Mouse   579 LKMNKPLKAKEAYLKALELDR--NNADLWYNLAIVYIELKEPNEALKNFNRALELNPKHKLALFN 641

  Fly    86 KEALMQKRLEIADLIVERNKKRDE--KALERYDNKRRAEI-------------QKEIQRETDMRE 135
            ...|||:..|:        |.|.|  |.|..|.|:...:.             :|:.:.|:.|::
Mouse   642 SAILMQESGEV--------KLRPEARKRLLNYVNEEPQDANGYFNLGMLAMDDKKDSEAESWMKK 698

  Fly   136 RVK---QFQENSVREALVV-DVRKEAKATP-KPDTLQYPP--SSG----------------GASR 177
            .:|   .|:......||:. ...||.||.| ..:.|:|.|  :.|                ||.:
Mouse   699 AIKLQPDFRSALFNLALLYSQTAKELKALPILEELLKYYPDHTKGLILKGDILMNQKKDIPGAKK 763

  Fly   178 LATPLMRPPMSSVRGSGRINV-------------------------NFTTQHKRVTPKR-ESQAA 216
            ....::....|:|:|...:.|                         .:..:|..:...| .|...
Mouse   764 CFEKILEMDPSNVQGKHNLCVVYFEEKELLKAERCLVETLALAPHEEYIQRHLSIVRDRISSSGI 828

  Fly   217 MEKAYAAAG---GPNANVQSPMESVDE 240
            :|:..|.|.   |.....:.|.|.|.|
Mouse   829 VEQPLAPADKTPGTEEREEIPSEDVKE 855

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14921NP_609491.1 p23_DYX1C1_like 4..81 CDD:107226 13/47 (28%)
Tmtc3NP_001103483.1 DUF1736 263..336 CDD:369859
TPR 1 417..450
PEP_TPR_lipo <448..807 CDD:274350 47/237 (20%)
TPR 2 451..484
TPR repeat 451..479 CDD:276809
TPR repeat 484..528 CDD:276809
TPR 3 486..518
TPR 4 533..567
TPR repeat 535..562 CDD:276809
TPR repeat 567..597 CDD:276809 7/17 (41%)
TPR 5 568..601 9/23 (39%)
TPR 6 602..635 5/32 (16%)
TPR repeat 602..630 CDD:276809 5/27 (19%)
TPR 7 673..706 4/32 (13%)
TPR repeat 673..702 CDD:276809 3/28 (11%)
TPR repeat 707..735 CDD:276809 7/27 (26%)
TPR 8 708..740 10/31 (32%)
TPR 9 741..775 3/33 (9%)
TPR repeat 741..770 CDD:276809 3/28 (11%)
TPR repeat 776..799 CDD:276809 3/22 (14%)
TPR 10 777..809 2/31 (6%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 829..897 8/27 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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