DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14921 and Kdm6a

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_006527657.1	Gene:	Kdm6a / 22289	MGIID:	1095419	Length:	1476	Species:	Mus musculus

Alignment Length:	168	Identity:	35/168 - (20%)
Similarity:	63/168 - (37%)	Gaps:	19/168 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NPP---IFFERHLAQEIDEMASFCRIFKNEARIVLVKKEKGLWPEMFQKLDKEALMQKRLEIA-- 97
            |||   |:.|.........:..||....|...::     :||...:  |||......|.|..|
Mouse   989 NPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVI-----RGLAGAL--KLDLGLFSTKTLVEANN 1046

  Fly    98 DLIVERNKKRDEKALERYDNKRRAEI-QKEIQRETDMRERVKQFQENSVREALVVDVRKEAKATP 161
            :.:||...:..:.|.|.:|.....:| ..|..|......:..|:|.:|.:|:|..:..|.:....
Mouse  1047 EHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKD 1111

  Fly   162 KPDTLQYPPSSGGASRLATPLMRPPMSSVRGSGRINVN 199
            ..|:......:.|..|      :.|..:::....|:::
Mouse  1112 HSDSESTSSDNSGKRR------KGPFKTIKFGTNIDLS 1143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	10/45 (22%)
Kdm6a	XP_006527657.1	TPR repeat	95..123	CDD:276809
		TPR	108..401	CDD:223533
		TPR repeat	131..161	CDD:276809
		TPR repeat	166..196	CDD:276809
		TPR repeat	207..235	CDD:276809
		TPR repeat	287..314	CDD:276809
		TPR repeat	319..349	CDD:276809
		TPR repeat	354..380	CDD:276809
		JmjC	1151..1215	CDD:214721
		JmjC	1185..1293	CDD:334913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900