DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14921 and Kdm6b

DIOPT Version :9

Sequence 1:	NP_609491.1	Gene:	CG14921 / 34547	FlyBaseID:	FBgn0032345	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_030101676.1	Gene:	Kdm6b / 216850	MGIID:	2448492	Length:	1642	Species:	Mus musculus

Alignment Length:	229	Identity:	47/229 - (20%)
Similarity:	89/229 - (38%)	Gaps:	80/229 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 EARIVLVKKEKGLWPEMFQKLDKEALM-----QKRLEIADLIV----------ERNKKRDEKALE 113
            |.:|.|:|.|.|         |||..:     ::||.:|||.:          .:|.|...|..|
Mouse  1100 ELKIRLIKVESG---------DKETFIASEVEERRLRMADLTISHCAADVMRASKNAKVKGKFRE 1155

  Fly   114 RYDNKRRAEIQKEIQRETDMRERVKQFQENSVREALVVDVRKEAKATPKPDTLQYPPSSGGASRL 178
            .|.:..:: ::.:|..|    |::.:.:.|....::.::.:::|.:   |..||:         .
Mouse  1156 SYLSPAQS-VKPKINTE----EKLPREKLNPPTPSIYLESKRDAFS---PVLLQF---------C 1203

  Fly   179 ATPLMRPPMSSVRG-SGRINVN---FTT--------QH---------------------KRVTPK 210
            ..|  |.|::.:|| :|.:.:|   |:|        :|                     :::.|.
Mouse  1204 TDP--RNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPC 1266

  Fly   211 RESQA----AMEKAYAAAGGPNANVQSPMESVDE 240
            ..|::    |....|.|:....:..|...||.||
Mouse  1267 ESSRSHTTIAKYAQYQASSFQESLQQEERESEDE 1300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14921	NP_609491.1	p23_DYX1C1_like	4..81	CDD:107226	6/16 (38%)
Kdm6b	XP_030101676.1	TPR repeat	106..136	CDD:276809
		JmjC	1342..1406	CDD:214721
		JmjC	1376..1484	CDD:396791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900