Protein Alignment CG6230 and PMR1

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: NP_011348.1
• Gene: PMR1 / 852709
• SGDID: S000003135
• Length: 950
• Species: Saccharomyces cerevisiae
• Alignment Length: 1095
• Identity: 229/1095 - (20%)
• Similarity: 398/1095 - (36%)
• Gaps: 291/1095 - (26%)

  Fly   164 PIRSSKLEDGSTQYYFVFQKTKYVWNEDRKTFRAVEFPVNGLLSTYSSSR--GLETEEDIKRATQ 226
            |..:|.|::.|.:...:...|....::...:.......|:..|....:.:  ||.:..:......
Yeast     5 PFNASLLDEDSNREREILDATAEALSKPSPSLEYCTLSVDEALEKLDTDKNGGLRSSNEANNRRS 69

  Fly   227 TYGNNEM-----EMVVPEFHELFIE-RATAPFFVFQVFSVGLWCMDDYWYYSLFTLFMLIAFECT 285
            .||.||:     |.:..:|...||| |.........|.|:.:..:||   ....||.:.|.....
Yeast    70 LYGPNEITVEDDESLFKKFLSNFIEDRMILLLIGSAVVSLFMGNIDD---AVSITLAIFIVVTVG 131

  Fly   286 IVKQQLRNMSEIRKMGNK--PYLIYAFRQNKWRHLGSDELLPGDLVSITRSQNDNIVPCDLVILR 348
            .| |:.|:...:..: ||  |...:..|..:..|:.:..|:|||||.......   :|.|:.|:.
Yeast   132 FV-QEYRSEKSLEAL-NKLVPAECHLMRCGQESHVLASTLVPGDLVHFRIGDR---IPADIRIIE 191

  Fly   349 G-SCIVDESMLTGESVPLMKESLESLDNLDVEMDAEGD---------GKLFVLFGGTKVVQHTAP 403
            . ...:|||.||||:.|:.|.|      ..:|..:..|         .:..:.:.||.|
Yeast   192 AIDLSIDESNLTGENEPVHKTS------QTIEKSSFNDQPNSIVPISERSCIAYMGTLV------ 244

  Fly   404 TKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENNVE---------------TFAFI 453
                   .:|...|.|:.||.|||         |||.....||:|               ..:.:
Yeast   245 -------KEGHGKGIVVGTGTNTS---------FGAVFEMMNNIEKPKTPLQLTMDKLGKDLSLV 293

  Fly   454 AFLMVFAVAAASYVWVKGSEDPERNRYKLFLECTLILTSIIPPDLPIELTLAVNTSLIQLTKLFV 518
            :|:::..:.....  ::|     |:..::|.....:..:.||..|||.:|:.:...::::.|...
Yeast   294 SFIVIGMICLVGI--IQG-----RSWLEMFQISVSLAVAAIPEGLPIIVTVTLALGVLRMAKRKA 351

  Fly   519 FCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVE------------GIAGLAPNGACVPIEKAEGN 571
            .......:...|.|.:.|.|||||||::::.|.            .:..|..|   ...:.:.||
Yeast   352 IVRRLPSVETLGSVNVICSDKTGTLTSNHMTVSKLWCLDSMSNKLNVLSLDKN---KKTKNSNGN 413

  Fly   572 -----------TVQVLACCHSLALLDDGLV--GDPLEKATLAAV-DWTLTKMDSVIPKRPQFKPL 622
                       |:.:...|::.:...:..:  |:|.:.|.|..: ::.:..:.:.:.|
Yeast   414 LKNYLTEDVRETLTIGNLCNNASFSQEHAIFLGNPTDVALLEQLANFEMPDIRNTVQK------- 471

  Fly   623 KIIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGAVKGAPEVI---------------QKMLREVP 672
              :|...|:|..|.|:...  |.|..|  |....||||.|.|               :|:.....
Yeast   472 --VQELPFNSKRKLMATKI--LNPVDN--KCTVYVKGAFERILEYSTSYLKSKGKKTEKLTEAQK 530

  Fly   673 ADYEKVYLEYARRGARVLA---LGIKDLGTLGAQRVREMKREEVECDLTFAGFLIISCPMKPDSK 734
            |...:.....|..|.||..   |.:.|..|        ...|::..||||.|.:.::.|.:|:.|
Yeast   531 ATINECANSMASEGLRVFGFAKLTLSDSST--------PLTEDLIKDLTFTGLIGMNDPPRPNVK 587

  Fly   735 SVIKELIQSSHKVVMITGDSPLTACHVARELRFTRKKLIILTPPEEDRKNNWSWVSIDGDQSYEL 799
            ..|::|:|....::||||||..||.::|:::     .:.::.|
Yeast   588 FAIEQLLQGGVHIIMITGDSENTAVNIAKQI-----GIPVIDP---------------------- 625

  Fly   800 DTKPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLG 864
                   |||        .::|:.|..:..:|   :..::..:.:.||..|:.|..::..|::.|
Yeast   626 -------KLS--------VLSGDKLDEMSDDQ---LANVIDHVNIFARATPEHKLNIVRALRKRG 672

  Fly   865 YCTLMCGDGTNDVGALKHANVGVSL---------------LTSAPVKRKRTEEEQQQAAANAAAI 914
            ....|.|||.||..|||.:::|||:               ||........|..|:.:...|
Yeast   673 DVVAMTGDGVNDAPALKLSDIGVSMGRIGTDVAKEASDMVLTDDDFSTILTAIEEGKGIFN---- 733

  Fly   915 AAQAQANANQQLTTRERALR--------RRQEHLNQTQARLQNALRD-----------MEEQTMV 960
              ..|.....||:|...||.        :....||..|....|.|.|           ::.:.|.
Yeast   734 --NIQNFLTFQLSTSVAALSLVALSTAFKLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMK 796

  Fly   961 KLGDASIAAPFTSKSSSIM---CVNHIIKQGRCTLVTTLQMF-KILALNALIQAYCQSVLYIDGI 1021
            |        |...::..|:   .:..::....|.:|.|:.:| |.:|.:..:.|
Yeast   797 K--------PPRKRTDKILTHDVMKRLLTTAACIIVGTVYIFVKEMAEDGKVTA----------- 842

  Fly  1022 KFSDTQATMQGIFIAACFLFITRAKPL------KTLSKVAPLPN-IFNFYTISTILSQ------- 1072
              .||..|.      .||:|......|      |::.::....| :||:....::|.|
Yeast   843 --RDTTMTF------TCFVFFDMFNALACRHNTKSIFEIGFFTNKMFNYAVGLSLLGQMCAIYIP 899

  Fly  1073 -FAVHFGT----------LYYLTSQANILAPPREGKVKLYIDMDAEEKTKYDPNI 1116
             |...|.|          |..::|...|:...|    ||:.....||.:.|..|:
Yeast   900 FFQSIFKTEKLGISDILLLLLISSSVFIVDELR----KLWTRKKNEEDSTYFSNV 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	229/1095 (21%)
		E1-E2_ATPase	310..515	CDD:278548	50/229 (22%)
		Cation_ATPase	<590..664	CDD:289987	19/76 (25%)
		COG4087	<850..901	CDD:226572	18/65 (28%)
PMR1	NP_011348.1	ATPase-IIA2_Ca	35..940	CDD:130585	220/1053 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910