Protein Alignment CG6230 and ENA1

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: NP_010325.1
• Gene: ENA1 / 851610
• SGDID: S000002447
• Length: 1091
• Species: Saccharomyces cerevisiae
• Alignment Length: 1066
• Identity: 215/1066 - (20%)
• Similarity: 359/1066 - (33%)
• Gaps: 366/1066 - (34%)

  Fly   210 SSSRGLETEEDIKRATQTYGNNEM---------EMVVPEFHELFIERATAPFFVFQVFSVGLWCM 265
            |.:.||..:|.:.| .:|.|.|.:         .||:   |::    ..|...|..:..:..:.|
Yeast    32 SLTEGLTQDEFVHR-LKTVGENTLGDDTKIDYKAMVL---HQV----CNAMIMVLLISMIISFAM 88

  Fly   266 DDY-------WYYSLFTLFMLI-AFECTIVKQQLRNMSEIRKMGNKPYLIYAFRQNKWRHLGSDE 322
            .|:       :..::..|..|: .::.|.....|:|:|...        .:..|..|...:.|.:
Yeast    89 HDWITGGVISFVIAVNVLIGLVQEYKATKTMNSLKNLSSPN--------AHVIRNGKSETINSKD 145

  Fly   323 LLPGDLVSITRSQNDNIVPCDLVILRGSCI-VDESMLTGESVPLMKESLESLDNLDVEMDAE--- 383
            ::|||:..:   :..:.:|.||.::..... .|||:|||||:|:.|::     ||....:.|
Yeast   146 VVPGDICLV---KVGDTIPADLRLIETKNFDTDESLLTGESLPVSKDA-----NLVFGKEEETSV 202

  Fly   384 GDGKLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKLLRTI------------- 435
            || :|.:.|..:.||:             |...|.||:|..|:..||:.:::
Yeast   203 GD-RLNLAFSSSAVVK-------------GRAKGIVIKTALNSEIGKIAKSLQGDSGLISRDPSK 253

  Fly   436 ----------------LFGANRATENNVETFAFIAFLMVFAVAAASYVWVKGSEDPERNRYKLFL 484
                            ..|.|..|..:.:.......|...||..|..|......|.:: |..::.
Yeast   254 SWLQNTWISTKKVTGAFLGTNVGTPLHRKLSKLAVLLFWIAVLFAIIVMASQKFDVDK-RVAIYA 317

  Fly   485 ECTLILTSIIPPDLPIELTLAVNTSLIQLTKLFVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLM 549
            .|  :..|:||..|.:.||:.::.....:....|...:...:...|.|...|.|||||||...::
Yeast   318 IC--VALSMIPSSLVVVLTITMSVGAAVMVSRNVIVRKLDSLEALGAVNDICSDKTGTLTQGKML 380

  Fly   550 VEGI-----AGLAPNGACVPIEKAEGNTVQV-----LACCHSLALLDDGLVG------------- 591
            ...|     ..:..:.:..|....|||...:     ....|:    :||.||
Yeast   381 ARQIWIPRFGTITISNSDDPFNPNEGNVSLIPRFSPYEYSHN----EDGDVGILQNFKDRLYEKD 441

  Fly   592 -----------DPLEKATLA-----------------------AVDWTLTKMDSVIP-------- 614
                       ..||.||||                       |:....||||  :|
Yeast   442 LPEDIDMDLFQKWLETATLANIATVFKDDATDCWKAHGDPTEIAIQVFATKMD--LPHNALTGEK 504

  Fly   615 -----------------KRPQFKPLKIIQRYHFSSALKRMSVLAGHLIPYS--NEVKHIGAVKGA 660
                             ::|.....:.|..:.|.|.:||||     .:.|:  ||..:|.. |||
Yeast   505 STNQSNENDQSSLSQHNEKPGSAQFEHIAEFPFDSTVKRMS-----SVYYNNHNETYNIYG-KGA 563

  Fly   661 PEVI------------QKMLREVPADYE----KVYLEYARRGARVLALGIKDL--GTLGAQRVRE 707
            .|.|            .|:......|.|    .|| ..:..|.|||....|..  ..:...:::.
Yeast   564 FESIISCCSSWYGKDGVKITPLTDCDVETIRKNVY-SLSNEGLRVLGFASKSFTKDQVNDDQLKN 627

  Fly   708 M--KREEVECDLTFAGFLIISCPMKPDSKSVIKELIQSSHKVVMITGDSPLTACHVARELRFTRK 770
            :  .|...|.||.|.|.:.|..|.:.::...:|:..|:...|.|:|||...||..:|:|:.....
Yeast   628 ITSNRATAESDLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPT 692

  Fly   771 KL----------IILTPPEEDRKNNWSWVSIDGDQSYELDTKPGSKKLSHLLATHDLCITGEGLQ 825
            .|          :::|..:           .||....|:|..|
Yeast   693 NLYHYSQEIVDSMVMTGSQ-----------FDGLSEEEVDDLP---------------------- 724

  Fly   826 YLQQNQPQYMRQLLPQITVCARFAPKQKELVITQL-KQLGYCTLMCGDGTNDVGALKHANVGVSL 889
                        :||  .|.||.:|:.|..:|..| ::..:|| |.|||.||..:||.||||:::
Yeast   725 ------------VLP--LVIARCSPQTKVRMIEALHRRKKFCT-MTGDGVNDSPSLKMANVGIAM 774

  Fly   890 LTSAPVKRKRTEEEQQQAAANAAAIAAQAQANANQQLTTRERALRRRQEHLNQTQARLQNALRDM 954
                              ..|.:.::
Yeast   775 ------------------GINGSDVS--------------------------------------- 782

  Fly   955 EEQTMVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTLVTTLQMFKILALNALIQAYCQSVLYID 1019
            :|.:.:.|.|.:.|:           :.:.:::|| .:...:|.|   .|..|.:...|::..|.
Yeast   783 KEASDIVLSDDNFAS-----------ILNAVEEGR-RMTDNIQKF---VLQLLAENVAQALYLII 832

  Fly  1020 GIKFSDTQA----------TMQGIFIAACF----LFITRAKPLKTLSKVAPLPNIFNFYTISTIL 1070
            |:.|.|...          .:..|.:.:||    |.:.:|.|  .|....|..:....:|...|:
Yeast   833 GLVFRDENGKSVFPLSPVEVLWIIVVTSCFPAMGLGLEKAAP--DLMDRPPHDSEVGIFTWEVII 895

  Fly  1071 SQFAVHF-----------GTLYYLTS 1085
            ..||...           |:||.:.|
Yeast   896 DTFAYGIIMTGSCMASFTGSLYGINS 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	215/1066 (20%)
		E1-E2_ATPase	310..515	CDD:278548	53/237 (22%)
		Cation_ATPase	<590..664	CDD:289987	30/147 (20%)
		COG4087	<850..901	CDD:226572	18/51 (35%)
ENA1	NP_010325.1	ATPase-IID_K-Na	11..1055	CDD:130586	215/1066 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910