Protein Alignment CG6230 and atp13a3

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: XP_009304446.2
• Gene: atp13a3 / 572029
• ZFINID: ZDB-GENE-120521-1
• Length: 1225
• Species: Danio rerio
• Alignment Length: 1267
• Identity: 327/1267 - (25%)
• Similarity: 559/1267 - (44%)
• Gaps: 302/1267 - (23%)

  Fly   123 LFCYWSVHVLAFLTCRRVKLPGANVL-------------AKV----VPTPN-------------- 156
            |..||........||.|..:..|.|.             |||    .|..|
Zfish    45 LLLYWMPEWCVKATCTRTTVRDAEVALLRSTDEFKRWFRAKVRIMLAPGKNPYDTLNSQTASPQA 109

  Fly   157 ---------NGNSKIVPIRSSKLEDGSTQY-YFVFQKTKYVWNEDRKTFRAVEFPVNGL------ 205
                     :.::||    |..:|....|. ||....|||.||:..:.|..::    ||
Zfish   110 NDHAHNMTDSTHNKI----SRSVESQQVQIRYFTLHSTKYFWNDTIQNFEVLK----GLEDLNIS 166

  Fly   206 -LSTYSS-SRGL-ETEEDIKRATQTYGNNEMEMVVPEFHELFIERATAPFFVFQVFSVGLWCMDD 267
             .|.:|. |.|| :.:::.:|.  .:|.||:::.||...:|.|:....||::||:|||.|||.|:
Zfish   167 CSSVHSKHSAGLNKNQQEYRRF--FFGLNEIDVKVPSLFKLLIKEVLNPFYIFQLFSVVLWCTDE 229

  Fly   268 YWYYSLFTL---FMLIAFECTIVKQQLRNMSEIRKMGNKPYLIYAFRQNKWRHLGSDELLPGDLV 329
            |:||::..:   |:.||.....:|:|...:.::....:...:.....:::.....|.:|:|||::
Zfish   230 YYYYAMAIVVMSFISIATSLYTIKKQYVMLHDMVATHSTVRVTVCRGESETEEALSTDLVPGDVI 294

  Fly   330 SITRSQNDNIVPCDLVILRGSCIVDESMLTGESVPLMKESLESLDNLDVEMDAEG-DG------- 386
            .|  ..|..|:|||.|::.|:|||:||||||||||:.|..|.     :.|.|.:| ||
Zfish   295 VI--PSNGTIMPCDAVLICGTCIVNESMLTGESVPVTKTDLP-----NPERDKKGSDGDQIYSTE 352

  Fly   387 --KLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENNVET 449
              |...||.||.|:|....|.|.::|       .|:||||:|::|:|:|:||:  .:.|:..:..
Zfish   353 EHKRHTLFCGTNVIQTRYYTGEMVKA-------VVVRTGFSTAKGQLIRSILY--PKPTDFKLYR 408

  Fly   450 FAFIAFLMVFAVAAASYVWVKG----SEDPERNRYKLFLECTLILTSIIPPDLPIELTLAVNTSL 510
            .|::..|.:.|||:..:::...    :::|.:   ::.::...|:|..:||.||..:|..:..:.
Zfish   409 DAYLFLLCLVAVASVVFIYSLVMKILNQEPVK---EIIVKSLDIITITVPPALPAAMTAGIVYAQ 470

  Fly   511 IQLTKLFVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVEGIAGLAPNGACVPIEKAEGNT--- 572
            .:|.|:.:|...|.||...|::.:.|||||||||.|.|.:.||..:..:......|:|:..:
Zfish   471 RRLRKVGIFSISPQRINICGQLNLVCFDKTGTLTEDGLDMWGIQRVEDSRFQHSEERADDKSLVT 535

  Fly   573 ---VQVLACCHSLALLDDGLVGDPLEKATLAAVDWTLTKM-------------------DSVIPK 615
               |..:|.||||..::..|.||||:.....|..|.|.:.                   :.::|.
Zfish   536 SRFVSCMATCHSLTKIEGQLSGDPLDLKMFEATGWILVEATEEETAHHDRIELTYVKPPNQLLPP 600

  Fly   616 RPQFKP-----------------LKIIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGA------V 657
             |...|                 :.|::::.|||||:||||:          |:.||.      :
Zfish   601 -PVISPEQDMELSELYELSASYMIGIVRQFSFSSALQRMSVV----------VRQIGERRMDAYL 654

  Fly   658 KGAPEVIQKMLRE--VPADYEKVYLEYARRGARVLALGIKDL-GTLGAQRVREMKREEVECDLTF 719
            ||||||:..:.::  ||.|:.:|..:|.::|.||:||..:.| ..|...:|:.:.|:::|.::.|
Zfish   655 KGAPEVVASLCKKESVPEDFAEVLEDYTKQGFRVIALAHRRLESKLTFHKVQNINRDQIEKNMDF 719

  Fly   720 AGFLIISCPMKPDSKSVIKELIQSSHKVVMITGDSPLTACHVARELRFTRK-KLIIL---TPPEE 780
            .|.:::...:|.::..|:.:|.:::.:.||:|||:.|||..|||:....:. .|:|:   .||::
Zfish   720 LGLIVMQNKLKTETPGVLDDLRRANIRTVMVTGDNMLTAISVARDCGMIQPLDLVIIADAVPPKD 784

  Fly   781 DR--KNNWSWVSIDGDQSYELDTKPGSKKL---------------SHLLATHDLCITGEGLQYLQ 828
            .:  |.||.:    .|:..:...||  .||               |.....:...::|:....:.
Zfish   785 GQAAKINWHY----ADKPSKHSNKP--TKLEEVEIILEDGHSVDESRSQEQYHFAMSGKSFAVII 843

  Fly   829 QNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLGYCTLMCGDGTNDVGALKHANVGVSLLTSA 893
            ::....:::|:...||.||.||.||..::..|:.:.|...|||||.||.||||.|:.|:||
Zfish   844 EHFQDLLQKLVLHGTVFARMAPDQKTQLVETLESVDYFVGMCGDGANDCGALKRAHAGISL---- 904

  Fly   894 PVKRKRTEEEQQQAAANAAAIAAQAQANANQQLTTRERALRRRQEHLNQTQARLQNALRDMEEQT 958
                                          .:|
Zfish   905 ------------------------------SEL-------------------------------- 907

  Fly   959 MVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTLVTTLQMFKILALNALIQAYCQSVLYIDGIKF 1023
                 :||:|:||||.:.||.||.::|::||..|:|:..:||.:||.::||....::||..|...
Zfish   908 -----EASVASPFTSTTPSITCVPNLIREGRAALITSFCVFKFMALYSIIQCLSVALLYSIGSNL 967

  Fly  1024 SDTQATMQGIFIAACFLF-----------ITRAKPLKTLSKVAPLPNIFNFYTISTILSQFAVHF 1077
            .|.|.....:.|....:|           :.|..|    |.:...|.:|:..|...|...|.:
Zfish   968 GDFQFLFIDMAIILLIVFTMSLNSAWKELVARRPP----SGLVSGPLLFSVLTQILICLAFQI-- 1026

  Fly  1078 GTLYYLTSQANILAPPREGKVKLYIDMD-----AEEKTKYDPNIVSSTVYIICLSLQVATIAVNY 1137
             ..:.|..:.:..:.|......|...|:     ...|.:...|.|::|::.|. |.|...:|:.:
Zfish  1027 -IAFLLIQRLDWYSKPDFYNCSLPHHMNNYSNSTGTKEENIVNDVNTTLFFIS-SFQYLIVAIVF 1089

  Fly  1138 -KGYPFMESLRSNRMLMYAIGASAALVILLSTGLAP--ELTEFFEIIDFPTDFR---------KT 1190
             ||.||.:.  |.:...:.:.|...::.:......|  .:.:|.|::..|..:|         .|
Zfish  1090 SKGKPFRQP--SYKNWPFVLSALILVIFMFFIMFFPISGIYKFLELVCVPLSWRVSMVIIILANT 1152

  Fly  1191 LLGVLV---LDIVGAFLLDRICSFLFGETRRK 1219
            ::.|::   :|:.|:..|..:|.     .|||
Zfish  1153 IVSVIIEGGIDMYGSKCLSWLCC-----RRRK 1179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	319/1236 (26%)
		E1-E2_ATPase	310..515	CDD:278548	69/218 (32%)
		Cation_ATPase	<590..664	CDD:289987	28/115 (24%)
		COG4087	<850..901	CDD:226572	20/50 (40%)
atp13a3	XP_009304446.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D172453at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920