Protein Alignment CG6230 and atp2a2b

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: XP_005161253.1
• Gene: atp2a2b / 568265
• ZFINID: ZDB-GENE-030131-867
• Length: 1041
• Species: Danio rerio
• Alignment Length: 1143
• Identity: 248/1143 - (21%)
• Similarity: 410/1143 - (35%)
• Gaps: 295/1143 - (25%)

  Fly   189 NEDRKTFRAVE--FPVNGLLSTYSSSRGLETEEDIKRATQTYGNNEM---------EMVVPEFHE 242
            |...||...|.  |.||       .|.||..|: :||..:.:|.||:         |:||.:|.:
Zfish     3 NAHTKTVEEVYSFFAVN-------ESTGLGLEQ-VKRQREKWGPNELPAEEGKSLWELVVEQFED 59

  Fly   243 LFIE---RATAPFFVFQVFSVGLWCMDDYWYYSLFTLFMLIAFECTIVKQQLRNMSEIRKMGN-K 303
            |.:.   .|....||...|..|...:..: ......|.:|||.....|.|:....:.|..:.. :
Zfish    60 LLVRILLLAACISFVLAWFEEGEETITAF-VEPFVILLILIANAIVGVWQERNAENAIEALKEYE 123

  Fly   304 PYLIYAFRQNK--WRHLGSDELLPGDLVSITRSQNDNIVPCD--LVILRGSCI-VDESMLTGESV 363
            |.:...:||::  .:.:.:.:::|||:|.:.....   ||.|  |..::.:.: ||:|:||||||
Zfish   124 PEMGKVYRQDRKTVQRIKARDIVPGDIVEVAVGDK---VPADIRLTSIKSTTLRVDQSILTGESV 185

  Fly   364 PLMKESLESLDNLDVEMDAEGDGKLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQ 428
            .::|.:....|...|..|     |..:||.||.:..             |..:|.|:.||.||..
Zfish   186 SVIKHTDPVPDPRAVNQD-----KKNMLFSGTNIAA-------------GKAVGVVVATGVNTEI 232

  Fly   429 GKLLRTILFGANRAT--ENNVETFAFIAFLMVFAVAAASYV--------------WVKGSEDPER 477
            ||:...:.......|  :..::.|......::..:..|.::              ||:|:
Zfish   233 GKIRDEMASTEQERTPLQQKLDEFGQQLSKVISLICIAVWIINIGHFNDPVHGGSWVRGA----- 292

  Fly   478 NRYKLFLECTLILTSIIPPDLPIELTLAVNTSLIQLTKLFVFCTEPFRIPFAGKVQICCFDKTGT 542
              ...|.....:..:.||..||..:|..:.....::.|..........:...|...:.|.|||||
Zfish   293 --VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGT 355

  Fly   543 LTTDNLMV------------------EGIAG--LAPNG-ACVPIEKAEGNTVQ------------ 574
            |||:.:.|                  ..|:|  .||:| .|     .||..||
Zfish   356 LTTNQMSVCRMFIVDQANGNTCSLKEFSISGSTYAPDGQVC-----HEGKPVQCSKFDALVEMAS 415

  Fly   575 VLACCHSLALLDDGLVG--DPLEKATLAAVDWTLTKMDSVIPKRPQFKPLKIIQRYHFSSALKRM 637
            :.|.|:..:|..:...|  :.:.:||..|:...:.||:..   ..:.|.|..::|.:..:::.:.
Zfish   416 ICALCNDSSLDYNEAKGVYEKVGEATETALTCLVEKMNVF---DTELKGLSKVERANACNSVIKQ 477

  Fly   638 SVLAGHLIPYSNEVKHIGA---------------VKGAPE-VIQK---------MLREVPADYEK 677
            .:.....:.:|.:.|.:..               |||||| ||.:         .:...|...||
Zfish   478 LMKKEFTLEFSRDRKSMSVYCTPNKARSSMGKMFVKGAPEGVIDRCTHIRVGGNKVPMTPGIKEK 542

  Fly   678 ---VYLEY--ARRGARVLALGIKDLGTLGAQRVRE--MKREEVECDLTFAGFLIISCPMKPDSKS 735
               |..||  .|...|.|||..:|........|.|  .:..|.|.||||.|.:.:..|.:.:..:
Zfish   543 IMSVIREYGTGRDTLRCLALATRDNPLSKESLVLEDSTRFVEYETDLTFVGCVGMLDPPRAEVAA 607

  Fly   736 VIKELIQSSHKVVMITGDSPLTACHVARELRFTRKKLIILTPPEEDRKNNWSWVSIDGDQSYELD 800
            .||...|:..:|:|||||:..||..:.|.:...         .|.|..:..::...:.|     |
Zfish   608 SIKLCRQAGIRVIMITGDNKGTAVAICRRIGIF---------GENDDVSRMAYTGREFD-----D 658

  Fly   801 TKPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLGY 865
            ....:::.:.|.|.   |.                          ||..|..|..::..|:....
Zfish   659 LSAAAQREAVLTAR---CF--------------------------ARVEPSHKSKIVEFLQSYDE 694

  Fly   866 CTLMCGDGTNDVGALKHANVGVSLLTSAPVKRKRTEEEQQQAAANAAAIAAQAQ----------- 919
            .|.|.|||.||..|||.|.:|:::.:...|  .:|..|...|..|.:.|.|..:
Zfish   695 ITAMTGDGVNDAPALKKAEIGIAMGSGTAV--AKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQ 757

  Fly   920 -------ANANQQLTTRERALRRRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSS 977
                   :|..:.:.....|.....|.|...|....|.:.|         |..:.|..|......
Zfish   758 FIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTD---------GLPATALGFNPPDLD 813

  Fly   978 IMCVNHIIKQGRCTLVTTLQMFKILALNALIQAYCQSVLYIDGIKFSDTQATMQGIFIAACFLFI 1042
            ||  :...:..|..|::....|:.||:...:.|                 ||:.    ||.:.||
Zfish   814 IM--SKPPRNAREPLISGWLFFRYLAIGCYVGA-----------------ATVG----AAAWWFI 855

  Fly  1043 TRAKPLKTLSKVAPLPNIFNFYTISTILS-----------QFAVHFGTLYYLTSQANILAPPREG 1096
            .....          |.: .||.:|..|.           |..: ||:.|.:|...::|
Zfish   856 AAEDG----------PRV-TFYQLSHFLQCAPDNPEFEGLQCEI-FGSPYPMTMALSVL------ 902

  Fly  1097 KVKLYIDM-DAEEKTKYDPNIVS----STVYI---ICLSLQVATIAVNYKGYPF---MESLRSNR 1150
               :.|:| :|......:.:::.    ..|::   ||||:.:..:.:..:..|.   :..|...:
Zfish   903 ---VTIEMCNALNSVSENQSLLHMPPWENVWLLGAICLSMSLHFLILYVEPLPMIFQITPLNVTQ 964

  Fly  1151 MLMYAIGASAALVILLSTGLAPELTEFF--EIIDFPTD 1186
            .||       .|.|.|...|..|:.:|.  ..:|.|.|
Zfish   965 WLM-------VLKISLPVILLDEVLKFAARNYLDKPKD 995

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	248/1143 (22%)
		E1-E2_ATPase	310..515	CDD:278548	49/225 (22%)
		Cation_ATPase	<590..664	CDD:289987	17/91 (19%)
		COG4087	<850..901	CDD:226572	16/50 (32%)
atp2a2b	XP_005161253.1	Cation_ATPase_N	4..72	CDD:279080	21/75 (28%)
		ATPase-IIA1_Ca	53..987	CDD:273452	228/1075 (21%)
		E1-E2_ATPase	93..340	CDD:278548	58/274 (21%)
		Cation_ATPase	419..526	CDD:289987	21/109 (19%)
		HAD	<602..710	CDD:289480	32/150 (21%)
		Cation_ATPase_C	782..984	CDD:279079	50/261 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000