Protein Alignment CG6230 and atp2c1

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: XP_003200287.2
• Gene: atp2c1 / 559574
• ZFINID: ZDB-GENE-060503-615
• Length: 922
• Species: Danio rerio
• Alignment Length: 1151
• Identity: 245/1151 - (21%)
• Similarity: 419/1151 - (36%)
• Gaps: 337/1151 - (29%)

  Fly   155 PNNGNSKIVPIRSSKLEDGSTQYYFVFQKTKYVWNEDRKTFRAVEFPVNGLLSTYSSSR--GLET 217
            |::.:..:||:.:||                          :|.|.|||.:.....:..  ||..
Zfish    14 PDSKDETMVPVLTSK--------------------------KASELPVNEVACALQADLQFGLNR 52

  Fly   218 EEDIKRATQTYGNNEMEMVVPE-FHELFIERATAPFFVF----QVFSVGLWCMDDYWYYSLFTLF 277
            || ::|....:|.||.::...| ..:.::.:...|..:.    .|.||.:...||   ....|:.
Zfish    53 EE-VERRRTYHGWNEFDISEDEPLWKKYLSQFKDPLILLLLSSAVISVLMRQFDD---AVSITVA 113

  Fly   278 MLIAFECTIVKQQLRNMSEIRKMGN-KPYLIYAFRQNKWRHLGSDELLPGDLVSITRSQNDNIVP 341
            ::|......| |:.|:...:.::|. .|...:..|:....||.:.||:|||.|.::..:.   ||
Zfish   114 IIIVVTVAFV-QEYRSEKSLEELGKLVPPECHCIREGHLEHLLARELVPGDTVCLSVGER---VP 174

  Fly   342 CDLVILRGSCI-VDESMLTGESVPLMKESL--ESLDNLDVEMDAEGDGKLFVLFGGTKVVQHTAP 403
            .||.:...:.: ||||.||||:.|..|.|.  .:..|.|:...:.      :.|.||.|
Zfish   175 ADLRLFESTDLAVDESSLTGETTPCTKTSAPQPAATNGDIASRSN------IAFMGTLV------ 227

  Fly   404 TKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENNVE-------------TFAFIAF 455
                 |.  |...|.||.||.::..|::.:  :..|..|.:..::             :...|..
Zfish   228 -----RC--GKAKGIVIGTGEDSEFGEVFK--MMQAEEAPKTPLQKSMDLLGKQLSLYSLGIIGV 283

  Fly   456 LMVFAVAAASYVWVKGSEDPERNRYKLFLECTLILTSI----IPPDLPIELTLAVNTSLIQLTKL 516
            :|...       |::|         |..|:...|..|:    ||..|||.:|:.:...::::.|.
Zfish   284 IMFVG-------WLQG---------KYILDMFTIGVSLAVAAIPEGLPIVVTVTLALGVMRMVKK 332

  Fly   517 FVFCTEPFRIPFAGKVQIC---CFDKTGTLTTDNLMV------EG----IAGLAPNGACVPIEKA 568
            .....   ::|....:..|   |.|||||||.:.:.|      :|    :.|:..|.:...:...
Zfish   333 RAIVK---KLPIVETLSCCNVICSDKTGTLTKNEMTVTHLFTSDGQHAEVTGIGYNNSGEILMDG 394

  Fly   569 E-----GNT-----VQVLACCHSLALLDDGLVGDPLEKATLA-AVDWTLTKMDSVIPKRPQFKPL 622
            |     .||     |:|...|:...:..:.|:|.|.|.|.:| |:...|..:      :.:|..|
Zfish   395 EVVHGISNTSISKIVEVGCVCNDAMIRHNTLMGRPTEGALIALAMKMGLEGL------QHEFVRL 453

  Fly   623 KIIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGAVKGAPEVIQKM------------LREVPADY 675
            :.|.   |:|..|.|:|...|..  ..:...:..||||.|.:.:.            |.....|:
Zfish   454 EEIP---FTSEQKWMAVRVVHRT--QRDKPGLFYVKGAYEQVIRFCTSYNSKGVTMPLNNQQRDF 513

  Fly   676 ---EKVYLEYARRGARVLALGI-KDLGTLGAQRVREMKREEVECDLTFAGFLIISCPMKPDSKSV 736
               :|.|:  ...|.||||... .::|:                 |||.|.:.|..|.:...|..
Zfish   514 YQQQKSYM--GSGGLRVLAFASGSEMGS-----------------LTFLGLVGIIDPPRAGVKEA 559

  Fly   737 IKELIQSSHKVVMITGDSPLTACHVARELRFTRKKLIILTPPEEDRKNNWSWVSIDGDQSYELDT 801
            :..||.|...|.|:||||..||..:|..|....|
Zfish   560 VATLISSGVAVKMVTGDSEETAVAIASRLGLYTK------------------------------- 593

  Fly   802 KPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLGYC 866
              ||:           |::|:   .:.|...|::.|::.::.|..|.:|:.|..::..|:.:|..
Zfish   594 --GSQ-----------CLSGD---EVDQMDIQHLSQIVHRVVVFYRASPRHKLKIVKSLQNIGAV 642

  Fly   867 TLMCGDGTNDVGALKHANVGVSLLTSAPVKRKRTEEEQQQAAANAAAIAAQAQANANQQLTTRER 931
            ..|.|||.||..|||.|::||::        .:|..:..:.||:...:        :....|...
Zfish   643 VAMTGDGVNDAVALKAADIGVAM--------GQTGTDVCKEAADMILV--------DDDFQTILS 691

  Fly   932 ALRRRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTLV--- 993
            |:...:...|    .::|.:|.....::..|...|:|                      ||:
Zfish   692 AIEEGKGIYN----NIKNFVRFQLSTSIAALTLISLA----------------------TLLNFP 730

  Fly   994 TTLQMFKILALNALIQAYCQSVLYIDGIKFSDTQATMQGIFIAACFLFITRAKPLKTLSKVAPLP 1058
            |.|...:||.:|.::.......|.::.:.:.                 :.|..|......:
Zfish   731 TPLNAMQILWINIIMDGPPAQSLGVEPVDWD-----------------VIRKPPRNVRDSI---- 774

  Fly  1059 NIFNFYTISTILSQFAVHFGTLYYLTSQANILAPPREGKVKLYIDMDAEEKTKYDPNIVSSTVYI 1123
             |.....:..::|.|.:..|||:.                 .:.::...|.|..| ..::.|.::
Zfish   775 -ITRSLIVKILVSAFIIVCGTLFV-----------------FWRELRDNEITPRD-TTMTFTCFV 820

  Fly  1124 I-----CLSLQVATIAVNYKGYPFMESLRSNRMLMYAIGAS---AALVILLSTGLAPELTEFFEI 1180
            .     .||.:..|..|:..|      |.||||..||:..|   ..|||..     |.|...|:
Zfish   821 FFDMFNALSSRSQTRMVHEMG------LCSNRMFCYAVLGSIMGQLLVIYF-----PPLQSVFQ- 873

  Fly  1181 IDFPTDFRKTLLGVLVLDIVGAF-LLDRICSFLFGETRRKSKVLNC 1225
                |:      .:.:||::..| |...:|  :..|..:|.:.|.|
Zfish   874 ----TE------SLSILDLLLLFGLTSSVC--VVSEIIKKIERLRC 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	236/1116 (21%)
		E1-E2_ATPase	310..515	CDD:278548	54/224 (24%)
		Cation_ATPase	<590..664	CDD:289987	21/74 (28%)
		COG4087	<850..901	CDD:226572	16/50 (32%)
atp2c1	XP_003200287.2	ATPase-IIA2_Ca	27..906	CDD:130585	240/1135 (21%)
		Cation_ATPase_N	30..98	CDD:279080	16/68 (24%)
		E1-E2_ATPase	110..343	CDD:278548	63/276 (23%)
		Cation_ATPase	414..497	CDD:289987	23/93 (25%)
		HAD_like	555..665	CDD:119389	40/156 (26%)
		Cation_ATPase_C	730..902	CDD:279079	44/235 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910