Protein Alignment CG6230 and SPoCk

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: NP_001262220.1
• Gene: SPoCk / 40495
• FlyBaseID: FBgn0052451
• Length: 1062
• Species: Drosophila melanogaster
• Alignment Length: 1059
• Identity: 230/1059 - (21%)
• Similarity: 404/1059 - (38%)
• Gaps: 263/1059 - (24%)

  Fly   207 STYSSSR-----------GLETEEDIKRATQTYGNNEMEMVV--PEFHELFIERATAPFFVF--- 255
            ||:|:|.           ||:..|...|| :..|:||:.:|.  |.:.: :||:...|..:.
  Fly   112 STHSASEVAGRLQVDVRTGLKWTEAKYRA-KIIGHNELLLVAEDPTWKK-YIEQFRNPLILLLLG 174

  Fly   256 -QVFSVGLWCMDDYWYYSLFTLFMLIAFECTIVKQ--QLRNMSEIRKMGNKPYLIYAFRQNKWRH 317
             .:.||.:...||   ....|:.:||......:::  ..:::.|::|:  .|...:..|:.:...
  Fly   175 SALVSVIMKQFDD---AVSITIAILIVVTVAFIQEYRSEKSLEELKKL--VPPECHCLREGRLDT 234

  Fly   318 LGSDELLPGDLVSITRSQNDNIVPCDLVILRG-SCIVDESMLTGESVPLMKESLESLDNLDVEMD 381
            ..:.||:|||:|.:.....   ||.|:.:... ...:|||..|||:.|..|.:...|:|.:|:
  Fly   235 FLARELVPGDIVHLNVGDR---VPADVRLFEAVDLSIDESSFTGETEPARKITDVLLNNTNVK-- 294

  Fly   382 AEGDGKLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENN 446
             :......:.|.||.|           |..:|.  |.|:.||..:..|::.:  :..|..|.:..
  Fly   295 -DHSNMKNIAFMGTLV-----------RCGNGK--GIVVSTGERSEFGEVFK--MMQAEEAPKTP 343

  Fly   447 VE--------TFAFIAFLMVFAVAAASYVWVKGSEDPERNRYKLFLECTLILTSIIPPDLPIELT 503
            ::        ..:|.:||::..:....  |::|....|     :|.....:..:.||..|||.:|
  Fly   344 LQKSMDILGAQLSFYSFLIIGVIMLLG--WLQGKPLSE-----MFNISVSLAVAAIPEGLPIVVT 401

  Fly   504 LAVNTSLIQLTKLFVFCTEPFRIPFAGKVQICCFDKTGTL-----------TTDNLMVEGIAGLA 557
            :.:...::::.|......:...:...|.|.:.|.||||||           |:|..|.: :.|..
  Fly   402 VTLALGVMRMAKRNSIVKKLPTVETLGCVNVICSDKTGTLTKNEMTATIIITSDGYMAD-VTGAG 465

  Fly   558 PNGA-------CVPIEKAEGNTVQVL---ACCHSLALLDDGLVGDPLEKATLAAVDWTLTKMDSV 612
            .|..       |..:|.|:.|...:|   |.|::..:.:..|:|.|.|.|.:|           |
  Fly   466 YNDQGEIHIRHCNNVEMAKTNITNLLEIGAVCNNAYIQNGTLLGQPTEGALVA-----------V 519

  Fly   613 IPKRPQFKPLK---IIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGAVKGAPEVI-------QKM 667
            ..|...:...:   .||.|.|||..|.|:|...|  .|:|..:.|...|||.|.:       |..
  Fly   520 AMKNGMYATAENYVRIQEYPFSSEQKMMAVKCIH--KYNNNKEEIFFAKGALETLLPQCTKYQFG 582

  Fly   668 LREVP------ADYEKVYLEYARRGARVLALGIKDLGTLGAQRVREMKREEVECDLTFAGFLIIS 726
            .:.||      |::.....|..|:|.|||||.          :.|.|:      ||.:.|.:.|:
  Fly   583 TQTVPLTKQNEAEFLAEAYEIGRKGLRVLALA----------KGRSMQ------DLIYCGLVGIT 631

  Fly   727 CPMKPDSKSVIKELIQSSHKVVMITGDSPLTACHV--ARELRFTRKKLIILTPP----------- 778
            .|.:|..:..|:.|:||..:|.|:|||:..||..:  :|.|:......|...|.
  Fly   632 DPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIDPSRRLQAVPTHAIPAWPTAGGVPLCSASA 696

  Fly   779 -------EEDRKNNWSWVSIDGDQSYELDTKPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMR 836
                   |...|.  .:::....|...|.|    ..|..:...|...::|:.:..:.::|   :.
  Fly   697 CCSTNCLENAMKE--IYLTALAQQGLPLVT----ANLIGIDTIHHQTLSGQEMDQMNEHQ---LD 752

  Fly   837 QLLPQITVCARFAPKQKELVITQLKQLGYCTLMCGDGTNDVGALKHANVGVSL-LTSAPVKRKRT 900
            ::...::|..|.:|:.|..::..|::.|....|.|||.||..|||.|::|::: .....|.::..
  Fly   753 KVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAA 817

  Fly   901 E---------------EEQQ------------QAAANAAAIAAQAQAN----ANQQLTTRERALR 934
            :               ||.:            |.:.:.||:|..|.|.    ||.
  Fly   818 DMILVNDDFHTIIAAIEEGKGIFYNIRNFVRFQLSTSIAALALIALATLMDIANP---------- 872

  Fly   935 RRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTLVTTLQMF 999
                 ||..|....|.:.|               .| .::|..:..|:|.:.:.:...|....:.
  Fly   873 -----LNAMQILWINIIMD---------------GP-PAQSLGVEPVDHDVLKQKPRNVKQPMIT 916

  Fly  1000 KILALNALIQAYCQSVLYID--------------GIKFSDTQATMQGIFIAACFLFITRAKPLKT 1050
            |.:.:|.|:.|   |::.:.              |....||..|.      .||:|......|..
  Fly   917 KSVVVNVLLSA---SIIVLGTLWVFQREMADGTLGKTKRDTTMTF------TCFVFFDMFNALSC 972

  Fly  1051 LSKVAPLPNIFNFYTISTILSQFAVHFGTLYYLTSQANILAPPREGKVKLYIDMDAEEKTKYDPN 1115
            .|:.   .::|.....:..:...||.|..:..:..   :..||      |.:....|..|.||
  Fly   973 RSQT---KSVFTIGLTTNRMFLLAVAFSIIGQMLV---VYFPP------LQMVFQTEALTPYD-- 1023

  Fly  1116 IVSSTVYIICLSLQVATIA 1134
                ..:::.|:..|..::
  Fly  1024 ----IFFLVSLTSSVLVVS 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	230/1059 (22%)
		E1-E2_ATPase	310..515	CDD:278548	47/213 (22%)
		Cation_ATPase	<590..664	CDD:289987	24/76 (32%)
		COG4087	<850..901	CDD:226572	16/51 (31%)
SPoCk	NP_001262220.1	ATPase-IIA2_Ca	110..1049	CDD:130585	230/1059 (22%)
		Cation_ATPase_N	112..179	CDD:279080	17/68 (25%)
		E1-E2_ATPase	191..425	CDD:278548	54/263 (21%)
		Cation_ATPase	496..579	CDD:289987	26/95 (27%)
		COG4087	<760..823	CDD:226572	18/62 (29%)
		Cation_ATPase_C	872..1044	CDD:279079	37/225 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840