Protein Alignment CG6230 and Atp13a2

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: XP_006239308.1
• Gene: Atp13a2 / 362645
• RGDID: 1307977
• Length: 1173
• Species: Rattus norvegicus
• Alignment Length: 1220
• Identity: 320/1220 - (26%)
• Similarity: 542/1220 - (44%)
• Gaps: 248/1220 - (20%)

  Fly   103 WNDVGF---IGVLAIAFLHILTLLFCY---WSVHVLAFLTCRRVKLPGANVLAKVVPTPNNGNSK 161
            |..:|:   :.:||    .|..|||.:   |.|.    |..|...|..|..|...:......:.:
  Rat    45 WRAIGYHAAVWMLA----GIPWLLFRWKPLWGVR----LRLRPCSLARAETLVIEIRDKEGSSRQ 101

  Fly   162 IVPIR---------------SSKLEDG----------------STQY-----------YFVFQKT 184
            :..::               .:|.|||                :||.           |::.|..
  Rat   102 LFTVQVQTEAVVDGSLELPSQAKAEDGRSLAAVGVAPESMWQDTTQLHRQKEAKQVLRYYILQGQ 166

  Fly   185 KYVWNEDRKTFRAVEFPVNGLL--STYSSSRGLETEEDIKRATQTYGNNEMEMVVPEFHELFIER 247
            :|||.|.::.|..|....:|..  ..:.||.||..::...|.| .||.|.:.:.|..:.:|.::.
  Rat   167 RYVWMETQQAFCQVSLLDHGRACDDIHCSSSGLSLQDQAVRKT-IYGPNVIGIPVKSYLQLLVDE 230

  Fly   248 ATAPFFVFQVFSVGLWCMDDYWYYSLFTLFMLIAFECTI----VKQQLRNMSEIRKMGNKPYLIY 308
            |..|::.||.||:.||..|.|::|:: .:|::.|....:    .::|...:.::.|:..:..:..
  Rat   231 ALNPYYGFQAFSIALWLADHYYWYAV-CIFLISAISICLSLYKTRKQSMTLRDMVKLSVRVQVCR 294

  Fly   309 AFRQNKWRHLGSDELLPGDLVSITRSQNDNIVPCDLVILRGSCIVDESMLTGESVPLMKESLESL 373
            ...:.:|  :.|.||:|||.:.:  .|...::|||..::.|.|:|:||.|||||:|::|.:|
  Rat   295 PGGEEEW--VDSSELVPGDCLVL--PQEGGMMPCDAALVAGECVVNESSLTGESIPVLKTAL--- 352

  Fly   374 DNLDVEMDAEG-------DGKLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKL 431
                    .||       ..:...||.||.|:|..|.....:       :..|.||||.|::|.|
  Rat   353 --------PEGPQPYCPETHRRHTLFCGTLVLQARAYLGPRV-------LAVVTRTGFCTAKGGL 402

  Fly   432 LRTILFGANRATENNVETFAFIAFLMVFAVAAASYVWVKGSEDPERNRY---KLFLECTLILTSI 493
            :.:||.....:.:....:..|:|.|.|.|:....|..:    ...|||.   ::.:....::|.:
  Rat   403 VSSILHPRPISFKFYRHSMKFVAALSVLALLGTIYSII----ILYRNRVPVKEIVIRALDLVTVV 463

  Fly   494 IPPDLPIELTLAVNTSLIQLTKLFVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVEGIA---- 554
            :||.||..:|:....:..:|....:||..|.||...||:::.|||||||||.|.|.:.|:.
  Rat   464 VPPALPAAMTVCTLYAQSRLRTQGIFCIHPLRINLGGKLRLVCFDKTGTLTEDGLDIMGVVPLKG 528

  Fly   555 ----GLAPNGACVPIEKAEGNTVQVLACCHSLALLDDGLVGDPLEKATLAAVDWTL--------- 606
                .|.|.    |.....|..::.|..||:|:.|.|.|||||::...:.:..|.|
  Rat   529 QMLLPLVPE----PCHLPPGPLLRALVTCHALSQLHDTLVGDPMDLKMVESTGWVLEEGSAAGSA 589

  Fly   607 --TKMDSVI---PKRPQF-----KPLKIIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGAVKGAP 661
              |::..|:   |:.||.     :|:.:::|:.|||||:||.|    ::.:....:....|||:|
  Rat   590 PETQVLVVMRPPPRGPQQQEESPEPVSVLRRFPFSSALQRMDV----VVTWPGATQPEAYVKGSP 650

  Fly   662 EVIQKML--REVPADYEKVYLEYARRGARVLALGIKDLGTL-GAQRVREMKREEVECDLTFAGFL 723
            |::..:.  ..||.|:.:|...|...|.||:||..|.|.|. ..:..:::.|:.||.:|:..|.|
  Rat   651 ELVASLCSPETVPRDFPQVLQSYTAAGYRVVALAGKPLPTAPSLEAAQQLTRDTVEQELSLLGLL 715

  Fly   724 IISCPMKPDSKSVIKELIQSSHKVVMITGDSPLTACHVARELRF--TRKKLIIL--TPPEEDRKN 784
            ::...:||.:..||:.|.::..:.||:|||:..||..||:....  |::.|.|:  |.||:.:..
  Rat   716 VMRNLLKPQTTPVIQTLRKTGIRTVMVTGDNLQTAVTVAKACGMVGTQEHLAIIHATHPEQGQPA 780

  Fly   785 NWSWV----------SIDGDQSYELDTKPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMRQLL 839
            ...::          :.|..|:.:...:|.|:       :..|.::|.....||::.|:.:.::|
  Rat   781 ALEFLPTEPSAAMNGAKDPVQATDYPVEPESQ-------SRHLALSGSTFAVLQKHFPKLLPKVL 838

  Fly   840 PQITVCARFAPKQKELVITQLKQLGYCTLMCGDGTNDVGALKHANVGVSLLTSAPVKRKRTEEEQ 904
            .|.||.||.||:||..::.:|::|.||..|||||.||.||||.|:||:||
  Rat   839 VQATVFARMAPEQKTQLVCELQRLQYCVGMCGDGANDCGALKAADVGISL--------------- 888

  Fly   905 QQAAANAAAIAAQAQANANQQLTTRERALRRRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAA 969
                                                  :||                  :||:.:
  Rat   889 --------------------------------------SQA------------------EASVVS 897

  Fly   970 PFTSKSSSIMCVNHIIKQGRCTLVTTLQMFKILALNALIQAYCQSVLYIDGIKFSDTQATMQGIF 1034
            ||||..:||.||..:|::|||:|.|:..:||.:||.:|.|.....:||.......|.|.....:|
  Rat   898 PFTSSMASIECVPTVIREGRCSLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLF 962

  Fly  1035 IAACF-LFITRAKPLKTLSKVAPLPNIFNFYTISTILSQFAVHFGTL---YYLTSQANILAPPRE 1095
            |.... :.::|..|..||.:..|...:.:...:.::|.|.|:..|..   |:|     ::|.|
  Rat   963 ITTTVAVLMSRTGPALTLVRARPPGALLSVPVLGSLLLQVALVAGIQLGGYFL-----VIAQP-- 1020

  Fly  1096 GKVKLYIDMDAEEKTKYDPNIVSSTVYIICLSLQVATIAVNYKGYPFMESLRSNRMLMYAIG--A 1158
            ..|.|...:.|.:..   ||..::.::.:.....:...|...||.||.:.|.:|...:.|:.  .
  Rat  1021 WFVPLNRTVPAPDNL---PNYENTVIFSLSGFQYLILAAAVSKGAPFRQPLYTNVPFLVALALLG 1082

  Fly  1159 SAALVILLSTGLAPELTEFFEIIDFPTDFRKTLLGVLVLDIVGAFLLDRI 1208
            |..:.::|..||.........|.|  :.|:..|||::..:.||||:|:.:
  Rat  1083 SVLVGLILVPGLLQGPLGLRNIAD--SSFKLLLLGLVAFNFVGAFMLESV 1130

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	311/1194 (26%)
		E1-E2_ATPase	310..515	CDD:278548	59/214 (28%)
		Cation_ATPase	<590..664	CDD:289987	26/92 (28%)
		COG4087	<850..901	CDD:226572	23/50 (46%)
Atp13a2	XP_006239308.1	P-ATPase-V	39..1116	CDD:273738	314/1204 (26%)
		P5-ATPase	39..>110	CDD:289194	15/72 (21%)
		E1-E2_ATPase	258..493	CDD:278548	65/260 (25%)
		Cation_ATPase	<621..658	CDD:289987	13/40 (33%)
		COG4087	<843..>892	CDD:226572	29/119 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54176
OrthoDB	1	1.010	-	-		D172453at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.930