Protein Alignment CG6230 and Atp13a1

DIOPT Version :10

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: NP_001099549.2
• Gene: Atp13a1 / 290673
• RGDID: 1306033
• Length: 1197
• Species: Rattus norvegicus
• Alignment Length: 1228
• Identity: 639/1228 - (52%)
• Similarity: 832/1228 - (67%)
• Gaps: 75/1228 - (6%)

  Fly    10 PGGAAGDAESYGKEMALQSGRP---KEPTKL---DDLVQYVSLHVRIPTPLTGVVLPFVPLYLSA 68
            ||||.|....       |.|||   ..|..:   |:||..|..:.|:.......||||..|...|
  Rat    14 PGGARGSGSP-------QPGRPGLAAGPALIASGDELVAAVWPYRRLALLRRLTVLPFAGLLYPA 71

  Fly    69 FYLWINVTG----GQENDTTNNDVITADNQTTTDNITTWNDVGFIGVLAIAFL---HILTLLFCY 126
               |:....    |..|                    :|..:....:||:|.:   |.||:|..:
  Rat    72 ---WLGAAASGCWGWGN--------------------SWTQIPEAALLALATICLAHALTILSGH 113

  Fly   127 WSVHVLAFLTCRRVKLPGANVLAKVVPTPNNGNSKIVPIRSSKLEDGSTQYYFVFQKTKYVWNE- 190
            ||||....|||.....|......|||||||||::::|.:...|.|||.....|.|||.||.::.
  Rat   114 WSVHAHCALTCTPEHDPNKVTFVKVVPTPNNGSTELVALHRDKGEDGLEVLSFEFQKIKYSYDAL 178

  Fly   191 DRKTFRAVEFPVNGLLSTYSSSRGLETEEDIKRATQTYGNNEMEMVVPEFHELFIERATAPFFVF 255
            ::|.|..|.|||....|.|.|:||.:.:.||:.|.:.:|:|:.||.||:|.|||.||||||||||
  Rat   179 EKKQFLPVAFPVGNAFSYYQSNRGFQEDSDIRAAEKKFGSNKAEMAVPDFSELFKERATAPFFVF 243

  Fly   256 QVFSVGLWCMDDYWYYSLFTLFMLIAFECTIVKQQLRNMSEIRKMGNKPYLIYAFRQNKWRHLGS 320
            |||.|||||:|:|||||:|||.||:|||.::|:||:|||||||||||||::|..:|..|||.:.|
  Rat   244 QVFCVGLWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIRKMGNKPHMIQVYRSRKWRPIAS 308

  Fly   321 DELLPGDLVSITRSQNDNIVPCDLVILRGSCIVDESMLTGESVPLMKESLESLDNLDVEMDAEGD 385
            |:::|||:|||.||..:|:||||:::|||.|||||:||||||||.|||.:|.| :.|..:|.:.|
  Rat   309 DDIVPGDIVSIGRSPQENLVPCDVLLLRGRCIVDEAMLTGESVPQMKEPIEDL-SPDRVLDLQAD 372

  Fly   386 GKLFVLFGGTKVVQHTAPTK--ESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENNVE 448
            .:|.|:|||||||||..|.|  ..|:..|.||:.:|:||||||||||||||||||..|.|.||:|
  Rat   373 ARLHVIFGGTKVVQHIPPQKATSGLKPVDNGCVAFVLRTGFNTSQGKLLRTILFGVKRVTANNLE 437

  Fly   449 TFAFIAFLMVFAVAAASYVWVKGSEDPERNRYKLFLECTLILTSIIPPDLPIELTLAVNTSLIQL 513
            ||.||.||:|||:|||:|||::|::||.||||||||||||||||::||:|||||:||||||||.|
  Rat   438 TFIFILFLLVFAIAAAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLAVNTSLIAL 502

  Fly   514 TKLFVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVEGIAGLAPNGACVPIEKAEGNTVQVLAC 578
            .||:::|||||||||||||::||||||||||:|:|:|.|:|||.......|:......|.:.||.
  Rat   503 AKLYMYCTEPFRIPFAGKVEVCCFDKTGTLTSDSLVVRGVAGLRDGKEVTPVSSIPIETHRALAS 567

  Fly   579 CHSLALLDDG-LVGDPLEKATLAAVDWTLTKMDSVIPKRPQFKPLKIIQRYHFSSALKRMSVLAG 642
            ||||..|||| |||||||||.|.||||||||.:.|.|:..:.:.|||.||:||:||||||||||.
  Rat   568 CHSLMQLDDGTLVGDPLEKAMLTAVDWTLTKDEKVFPRSIKTQGLKIHQRFHFASALKRMSVLAS 632

  Fly   643 HLIPYSNEVKHIGAVKGAPEVIQKMLREVPADYEKVYLEYARRGARVLALGIKDLGTLGAQRVRE 707
            :....|.::.:|.|||||||.:..|..:.|.||..::.|.:|.||||||||.|:||.|..|:.||
  Rat   633 YEKLGSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGYKELGHLTHQQARE 697

  Fly   708 MKREEVECDLTFAGFLIISCPMKPDSKSVIKELIQSSHKVVMITGDSPLTACHVARELRFTRK-K 771
            :|||.:||.|.|.||:::|||:|.|||:||:|:..:||:|||||||:||||||||:||.|..| .
  Rat   698 VKREALECSLKFVGFIVVSCPLKADSKAVIREIQNASHRVVMITGDNPLTACHVAQELHFIDKAH 762

  Fly   772 LIILTPPEEDRKNNWSWVSIDGDQSYELDTKPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMR 836
            .:||.||.| :.....|.||  |.|..|....||.|.  |...|.||:||:||.:||...||.:.
  Rat   763 TLILHPPSE-KGQPCEWRSI--DNSIVLPLTLGSPKA--LALEHALCLTGDGLAHLQAVDPQQLL 822

  Fly   837 QLLPQITVCARFAPKQKELVITQLKQLGYCTLMCGDGTNDVGALKHANVGVSLLTSAP---VKRK 898
            .|:|.:.|.||.||||||.|||.||:|||.|||||||||||||||||:|||:||.:||   |:|:
  Rat   823 HLIPHVQVFARVAPKQKEFVITSLKELGYVTLMCGDGTNDVGALKHADVGVALLANAPERVVERR 887

  Fly   899 RTEEEQQQAAANAAAIAAQAQANANQQLTTRERALRRRQEHLNQTQARLQNALRDMEEQT--MVK 961
            |...:....:.:...::         :.|.::.||...:|.....:.||...|||:|:::  :||
  Rat   888 RRPRDSPVLSNSGPRVS---------RSTKQKSALLSPEEPPASHRDRLSQVLRDLEDESTPIVK 943

  Fly   962 LGDASIAAPFTSKSSSIMCVNHIIKQGRCTLVTTLQMFKILALNALIQAYCQSVLYIDGIKFSDT 1026
            |||||||||||||.|||.|:.|:||||||||||||||||||||||||.||.|||||::|:||||.
  Rat   944 LGDASIAAPFTSKLSSIQCICHVIKQGRCTLVTTLQMFKILALNALILAYSQSVLYLEGVKFSDF 1008

  Fly  1027 QATMQGIFIAACFLFITRAKPLKTLSKVAPLPNIFNFYTISTILSQFAVHFGTLYYLTSQANILA 1091
            |||:||:.:|.|||||:|:|||||||:..|||||||.|||.|::.||:|||.:|.||..:|...:
  Rat  1009 QATLQGLLLAGCFLFISRSKPLKTLSRERPLPNIFNLYTILTVMLQFSVHFLSLVYLYREAQARS 1073

  Fly  1092 PPREGKVKLYIDMDAEEKTKYDPNIVSSTVYIICLSLQVATIAVNYKGYPFMESLRSNRMLMYAI 1156
            |.::   :.::|:..|    ::|::|:|||||:.:::|:||.|:||||.||||||..|:.|::::
  Rat  1074 PEKQ---EQFVDLYKE----FEPSLVNSTVYIMAMAMQMATFAINYKGPPFMESLPENKPLVWSL 1131

  Fly  1157 GASAALVILLSTGLAPELTEFFEIIDFPTDFRKTLLGVLVLDIVGAFLLDRICSFLFG 1214
            ..|...::.|..|.:|:....|.::|.|.:|:..:..||.||...|.|.||:..|..|
  Rat  1132 AVSLMAIMGLLLGSSPDFNSQFGLVDIPVEFKLVIGQVLALDFGLALLADRVLQFFLG 1189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-type_ATPase_cation	220..1152	CDD:319843	549/940 (58%)
Atp13a1	NP_001099549.2	P-type_ATPase_cation	208..1127	CDD:319843	549/940 (58%)