Protein Alignment CG6230 and catp-5

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: NP_001309699.1
• Gene: catp-5 / 181067
• WormBaseID: WBGene00019493
• Length: 1202
• Species: Caenorhabditis elegans
• Alignment Length: 1272
• Identity: 327/1272 - (25%)
• Similarity: 537/1272 - (42%)
• Gaps: 253/1272 - (19%)

  Fly    83 TTNNDVI-TADNQTT------TDN----ITTWNDVGFIGVLAIA--------------------F 116
            ||.|.|. |.||.:|      .||    .|::|.    |.|.|.                    .
 Worm    12 TTRNRVYDTTDNPSTKIMKREKDNPKAKTTSFNQ----GKLNIGEETCDLYAYKETIGRQILFWL 72

  Fly   117 LHILTL----LFCYWSVHVLAFL--------TCRRV---KLPGANVLAKVVPTPNN-GNSKIVPI 165
            |.|:||    |..||...:...:        .|..|   .:.|...:.:|....:: |.::  |.
 Worm    73 LTIVTLGFYQLLAYWVKSLFVKVRFQPTSHDECEYVMVEDIHGTQTIKEVFKAESDVGLAR--PT 135

  Fly   166 RSSKLEDGSTQYYFVFQKTKYVWNE-DRKTFRAVEFPVNGLLSTYSSSR----GLETEEDIKRAT 225
            ||.|.|......:|.::|.||:|.| |::.....:.......:.|....    ||: |:|:..:.
 Worm   136 RSGKQEKVKVMRFFTYRKIKYIWYEKDQEWLNPADMDSAAPFNIYQKLTLDVIGLK-EQDVIASR 199

  Fly   226 QTYGNNEMEMVVPEFHELFIERATAPFFVFQVFSVGLWCMDDYWYYSLFTLFMLIAFECTIVKQQ 290
            :.|..|.:.:.:.....:..:....||::||.|||.||..|:|.||:...:.:.:......|.|.
 Worm   200 KIYNMNALALALTPILVILFKEVLGPFYLFQCFSVALWYSDNYAYYASVIVIITVGSAAVAVYQM 264

  Fly   291 LRNMSEIRKMGNKPYLIYAFRQNKWRHLGSDELLPGDLVSITRSQNDNIVPCDLVILRGSCIVDE 355
            ......||.|......:...|......:.:.|::|.|::.:  ..|..|:|||.:::.|:.||:|
 Worm   265 RAQEKRIRNMVGDTISVIVRRDGHDITIDASEIVPMDILIL--PSNTFILPCDCLLMNGTVIVNE 327

  Fly   356 SMLTGESVPLMKESLESLDNLDVEMDAEGDGKLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVI 420
            :||||||||:.|.||:..|....|:....:.....||.||.|:|    |:.....|   .:..||
 Worm   328 AMLTGESVPVTKASLKEADECGPEIRLSSEHNRHTLFSGTTVLQ----TRNYKGQP---VMARVI 385

  Fly   421 RTGFNTSQGKLLRTILFGANRATENNVETFAFIAFLMVFAVAAASYVWVKGSEDPERNRYKLFLE 485
            ||||:|.:|:|:|:|::...:..|...:...||..|...|:....|..::.....|..:: :.:.
 Worm   386 RTGFSTLKGQLVRSIMYPKPQEKEALKDVMVFILVLGFIALIGFIYTVIEMVSRGESLKH-IIIR 449

  Fly   486 CTLILTSIIPPDLPIELTLAVNTSLIQLTKLFVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMV 550
            ...|:|.::||.||..:::.:..:..:|.|..:|||.|..:...|.:.:.|||||||||.|.|..
 Worm   450 SLDIITIVVPPALPAAMSVGIINANSRLKKKKIFCTSPTTVNVCGLINVACFDKTGTLTEDGLDF 514

  Fly   551 EGIAGLAPNGACVP---------------IEKAEGNTVQVLACCHSLALLDDGLVGDPLEKATLA 600
            ..:..:..|....|               .|.|..|.|...|.||||..:|..|.|||||...:.
 Worm   515 NCLKAIRKNEDGKPEFTSEFEELDPVKLSAENANLNIVVAAASCHSLTRIDGTLHGDPLELILVE 579

  Fly   601 AVDWTLTK----------MDSVIPK-----------RPQFKPLKIIQRYHFSSALKRMSVLAGHL 644
            ...|.:.:          .|:|.|.           .|:.....:|:::.|:|||:||||:
 Worm   580 KSKWIIEEAVNSDEETQDFDTVQPTVLRPPPEQATYHPENNEYSVIKQHPFNSALQRMSVI---- 640

  Fly   645 IPYSNEVKH-----IGAVKGAPEVIQKML--REVPADYEKVYLEYARRGARVLALGIKDLGTLGA 702
              .|...:|     :...||:||:|..:.  ..:|.||.:|..|||:||.|::|:..|.: .|..
 Worm   641 --ISTPSEHSAHDMMVFTKGSPEMIASLCIPDTIPEDYMEVVDEYAQRGFRLIAVASKAV-HLNF 702

  Fly   703 QRVREMKREEVECDLTFAGFLIISCPMKPDSKSVIKELIQSSHKVVMITGDSPLTACHVARELRF 767
            .:..:..|:.:|.:|.|.|.:::...:|..:.|||.||..::.:.||:|||:.|||..||||...
 Worm   703 AKALKTPRDIMESELEFLGLIVMENRLKDVTLSVINELSVANIRCVMVTGDNLLTAMSVARECGI 767

  Fly   768 TR--KKLIILTPPEEDR----------KNNWSWVSIDGDQSYELDTKPGSKKLSHLLATHDLCIT 820
            .|  ||..::|..:.::          |.:.|  |.:.|...:.:.:...:|.....||:.:.|.
 Worm   768 IRPTKKAFLITHSKTEKDPLGRTKLFIKESVS--SSENDIDTDSEVRAFDRKAVLRTATYQMAIA 830

  Fly   821 GEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLGYCTLMCGDGTNDVGALKHANV 885
            |.....:....|:.:.::.....|.||.||.||..:|..|:::|....|||||.||..|||.|:.
 Worm   831 GPTYSVITHEYPELVDRITAMCDVYARMAPDQKAQLIGALQEIGAKVSMCGDGANDCAALKAAHA 895

  Fly   886 GVSLLTSAPVKRKRTEEEQQQAAANAAAIAAQAQANANQQLTTRERALRRRQEHLNQTQARLQNA 950
            |:||                                                     :||
 Worm   896 GISL-----------------------------------------------------SQA----- 902

  Fly   951 LRDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTLVTTLQMFKILALNALIQAYCQSV 1015
                         :|||||||||....|.||..:||:|||.|||:..:.|.:|..:|.:.....:
 Worm   903 -------------EASIAAPFTSNVPDIRCVPTVIKEGRCALVTSYAVSKYMAAYSLNEFLSVML 954

  Fly  1016 LYIDGIKFSDTQ-ATMQGIFIAACFLFITRAKPLKTLSKVAPLPNIFNFYTISTILSQFAVHFGT 1079
            ||.||...||.| ..:..:.|....||:...:..:.||.:.| |.     .::|....|:| ||.
 Worm   955 LYNDGTNISDGQFLYIDLVLITLVALFLGNTEASRKLSGIPP-PR-----RLATSAFYFSV-FGQ 1012

  Fly  1080 LYY--LTSQANILAPPREGKVKLYIDMDAEEKTKYDPN---------IVSSTVYIICLSLQVATI 1133
            :::  :|.....|.              ...::.|.||         ::.:||:.....:.:...
 Worm  1013 MFFNIITQTTGYLL--------------VRGQSWYVPNPEELDNTTTMIGTTVFFTSCCMYLGYA 1063

  Fly  1134 AVNYKGYPFMESLRSNRML---MYAIGASAALVILLSTGLAPELTEFFEIIDFPTDFRKTLLGVL 1195
            .|..||:|:..|:.:|.:|   ::.|||...::|..:.|....|..|..:   |:...:.:|  |
 Worm  1064 FVYSKGHPYRRSVFTNWLLCGIIFVIGAINMVMIFTNMGFLMNLMGFVYV---PSTSMRFIL--L 1123

  Fly  1196 VLDIVGAFL--------LDRICSFLFGETRRKSKVLN 1224
            .:.:.|.||        ::::.:..|....|:.::.|
 Worm  1124 AISLAGVFLSLLYEHFFVEKVVAIHFESYLRQRRLRN 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	307/1194 (26%)
		E1-E2_ATPase	310..515	CDD:278548	59/204 (29%)
		Cation_ATPase	<590..664	CDD:289987	25/99 (25%)
		COG4087	<850..901	CDD:226572	20/50 (40%)
catp-5	NP_001309699.1	P-ATPase-V	52..1125	CDD:273738	306/1191 (26%)
		P5-ATPase	52..154	CDD:289194	18/103 (17%)
		E1-E2_ATPase	247..490	CDD:278548	69/252 (27%)
		Cation_ATPase	<614..667	CDD:289987	17/58 (29%)
		HAD_like	<846..910	CDD:304363	31/134 (23%)
		Cation_ATPase_C	966..1136	CDD:295563	40/195 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S925
OMA	1	1.010	-	-		QHG54176
OrthoDB	1	1.010	-	-		D172453at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.880