Protein Alignment CG6230 and pmr-1

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: NP_001021862.1
• Gene: pmr-1 / 173176
• WormBaseID: WBGene00004063
• Length: 978
• Species: Caenorhabditis elegans
• Alignment Length: 1146
• Identity: 237/1146 - (20%)
• Similarity: 415/1146 - (36%)
• Gaps: 342/1146 - (29%)

  Fly   184 TKYVWNEDRKTFRAVEFPVNGLLSTYSSS---------------RGLETEEDIKRATQTYGNNEM 233
            |.::..:..|:....:..:..|.|..::|               .||.|.|..:| .|.:|.||.
 Worm    61 TNHISKDRSKSISKDDIMIETLTSEQAASHEVVPCTHQLRTNLEEGLTTAEATRR-RQYHGYNEF 124

  Fly   234 EMVVPE-FHELFIERATAPFFVFQVFS--VGLWCMDDYWYYSLFTLFMLIAFECTIVKQ--QLRN 293
            ::...| .::.::|:...|..:..:.|  |.: .|..|......|:.::|......|::  ..:.
 Worm   125 DVGEEEPIYKKYLEQFQNPLILLLLASAFVSI-VMKQYDDAISITVAVVIVVTVGFVQEYRSEKT 188

  Fly   294 MSEIRKMGNKPYLIYAFRQNKWRHLGSDELLPGDLVSITRSQNDNIVPCDLVILRG-SCIVDESM 357
            :.::.|:  .|...:..|..|...:.:.||:|||:|.:.....   :|.||.|... |..:|||.
 Worm   189 LEQLTKL--VPPTCHVLRDGKEAMMLARELVPGDIVLLNTGDR---IPSDLRIAESFSLQIDESS 248

  Fly   358 LTGESVPLMKES----LESLDNLDVEMDAEGDGKLFVLFGGTKVVQHTAPTKESLRAPDGGCIGY 418
            ||||:.|..||:    ..|....|||      ....:.|.||.|..             |...|.
 Worm   249 LTGETEPKHKETRSVPAASATGSDVE------HLTCIAFMGTLVCA-------------GRGRGI 294

  Fly   419 VIRTGFNTSQGKLLRTILFGANRAT-----------ENNVETFAFIAFLMVFAVAAASYVWVKGS 472
            ||.|..|:..|::::.::...:..|           :.::.:|..||.:.:..:...
 Worm   295 VISTAANSQFGEVVKMMMGEESPKTPLQKSMDDLGKQLSIYSFGVIAVIFLIGMFQG-------- 351

  Fly   473 EDPERNRYKLFLECTLILTSIIPPDLPIELTLAVNTSLIQLTKLFVFCTEPFRIPFAGKVQICCF 537
                ||...:|.....:..:.||..|||.:.:.:...::::.|......:...:...|.|.:.|.
 Worm   352 ----RNVVDMFTIGVSLAVAAIPEGLPIVVAVTLAIGVMRMAKRRAVVKKMPAVETLGCVTVICS 412

  Fly   538 DKTGTLTTDNLMVEGIAGLAPNGACVPIE----KAEGNTVQVLA-------------------CC 579
            |||||||.:.:..:.||  .|.|....|.    .|||..||...                   .|
 Worm   413 DKTGTLTKNEMTAQAIA--TPEGKLAEITGIGYSAEGGVVQYQGEQVHQWTHPEFARIIEAGLVC 475

  Fly   580 HSLALLDDGLVGDPLEKATLAAVDWTLTKMDSVIPKRPQFKPLKIIQRYHFSSALKRMSVLAGHL 644
            ::..:..|.|:|.|.|.|.:            |:.|:.|.:.::        |..||:..:
 Worm   476 NNATIEADKLIGQPTEGAIV------------VLAKKAQLEGVR--------SEYKRLREM---- 516

  Fly   645 IPYSNEVKHIGA------------VKGAPEVIQKMLREVPADY-----EKVYLEYARRGARVLAL 692
             |:|::.|.:|.            :|||   :.::|.:....|     .|...:|:|:  .:|.:
 Worm   517 -PFSSDTKWMGVQCADAHGQNVYFIKGA---LDRVLDQCGTYYSSDNQRKQCDQYSRQ--HILEI 575

  Fly   693 GIKDLGTLGAQRVREMKREEVECDLTFAGFLIISCPMKPDSKSVIKELIQSSHKVVMITGDSPLT 757
            | |:||..|. ||..:.|.|....|.|.|.:.:..|.:|.:...|..:..|...|.:||||:..|
 Worm   576 G-KELGQKGL-RVLGLARGESMQSLMFLGMIGMMDPPRPGAADAISIVKASGVDVKLITGDAMET 638

  Fly   758 ACHVARELRFTRKKLIILTPPEEDRKNNWSWVSIDGDQSYELDTKPGSKKLSHLLATHDLCITGE 822
            |..:.:.|                                            .:|::.|.|::|
 Worm   639 AQSIGQSL--------------------------------------------GILSSSDSCLSG- 658

  Fly   823 GLQYLQQNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLGYCTLMCGDGTNDVGALKHANVGV 887
              |.:.|.....:..::.|:||..|.:|:.|..::..|:.||....|.|||.||..|||.|::||
 Worm   659 --QQVDQMSDHDLELVIRQVTVFYRASPRHKLKIVKALQALGEVVAMTGDGVNDAVALKKADIGV 721

  Fly   888 SL-LTSAPVKRKRTEEEQQQAAANAAAIAAQAQANANQQLTTRERALRRRQEHLNQTQARLQNAL 951
            :: :....|.:
 Worm   722 AMGVCGTDVCK------------------------------------------------------ 732

  Fly   952 RDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTL--VTTLQMFKILALNALIQAYCQS 1014
               |...|:...|     .|::.:::       |::|:...  :|....|::....|.:.....|
 Worm   733 ---EAADMILCDD-----DFSTMTAA-------IEEGKAIYHNITNFVRFQLSTSVAALSLIAAS 782

  Fly  1015 VLYIDGIKFSDTQATMQGIFIAACFLFITRAKPLKTLSKVAPLPN-------------IFNFYTI 1066
            .::    ||.:....||.::|.    .|....|.::|. |.|:.:             :.....|
 Worm   783 TMF----KFDNPLNAMQILWIN----IIMDGPPAQSLG-VEPVDDDIIRQRPRNTKQPMLTGKLI 838

  Fly  1067 STILSQFA-VHFGTLYYLTSQANILAPPREGKVKLYIDMDAEEKTKYDPNIVSSTVYII-----C 1125
            :.||:..| :..|||..                 .|.:|.|:.|.......::.|.:::     .
 Worm   839 ADILASAAIIVVGTLSV-----------------FYKEMSADNKVTPRDTTMTFTCFVLFDMWNA 886

  Fly  1126 LSLQVATIAVNYKGYPFMESLRSNRMLMYAIGASAALVI-LLSTGLAPELTEFFEIIDFPTDFRK 1189
            ||.:.:...:      :...||.||  |:::..||:|:. ||....|| |...|:     |:
 Worm   887 LSCRSSRKMI------WQIGLRRNR--MFSLAVSASLICQLLVIYWAP-LQHIFQ-----TE--- 934

  Fly  1190 TLLGVLVLDIVGAFLLDRICS--FLFGETRR----KSKVLN 1224
                  .|.:.....|..|.|  |:|.|||:    :||.||
 Worm   935 ------ALSLFDLIFLTTITSSVFIFNETRKYFSLRSKSLN 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	224/1107 (20%)
		E1-E2_ATPase	310..515	CDD:278548	50/220 (23%)
		Cation_ATPase	<590..664	CDD:289987	17/85 (20%)
		COG4087	<850..901	CDD:226572	18/51 (35%)
pmr-1	NP_001021862.1	ATPase-IIA2_Ca	81..967	CDD:130585	232/1122 (21%)
		Cation_ATPase_N	98..155	CDD:279080	13/57 (23%)
		E1-E2_ATPase	181..402	CDD:278548	53/256 (21%)
		Cation_ATPase	474..554	CDD:289987	21/107 (20%)
		HAD_like	610..723	CDD:119389	38/159 (24%)
		Cation_ATPase_C	790..961	CDD:279079	46/215 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910