Protein Alignment CG6230 and anne

DIOPT Version :10

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: XP_061510158.1
• Gene: anne / 1270659
• VectorBaseID: AGAMI1_003134
• Length: 1406
• Species: Anopheles gambiae
• Alignment Length: 1342
• Identity: 329/1342 - (24%)
• Similarity: 544/1342 - (40%)
• Gaps: 387/1342 - (28%)

  Fly   106 VGFI---GVLAIAFLHILTLLFCYWSVHVLAFLTCRRVKLPGA---------------------- 145
            |||:   |:|.         |..:|..|.|...|.|...|..|
Mosquito   166 VGFLLTFGILR---------LVMHWRQHWLLLATHRECSLDRAEKVLIHEAYQRKHDLYYVKDVI 221

  Fly   146 ----NVLAKVVPT----PNNGNSKIV--------------------PIR------SSKLEDGSTQ 176
                :|:.::|.:    |::.|::.|                    |.:      ..:.|..||.
Mosquito   222 TLSGDVVREIVDSEKKKPSSTNARNVIKELTQNGIPDYGAFLRTLDPFQVAYHRTGGRFEHASTM 286

  Fly   177 YYFVFQKTKYVWNEDRKTF---RAVEFPVNGLLSTYSSSRGLET-EEDIKRATQTYGNNEMEMVV 237
            .||..:|.:|:|.:..|.|   :.::..|..:|..:  ::||.. |:.|:|.  .||:||:.:.:
Mosquito   287 RYFSCKKLRYIWCDQAKKFVKLQGLDVEVPSVLIHH--TKGLSVYEQSIRRL--IYGSNEIFIPL 347

  Fly   238 PEFHELFIERATAPFFVFQVFSVGLWCMDDYWYYSLFTLFMLIAFECTIVKQQLRNMSEIRKMGN 302
            .....|.......||:|||:|||.||...:|:||:: .:.::.||..|:        |.|:...|
Mosquito   348 RSVLTLLFLEVLNPFYVFQIFSVVLWFFYEYYYYAV-VIILMSAFGITV--------SIIQTQRN 403

  Fly   303 KPYLIYAFRQNKWRHLGSDELL----------PGDLVSITRSQNDNIVPCDLVILRGSCIVDESM 357
            :..|....|......:..|.:|          |||::.|..:  ...:.||.|:|.|:||:||||
Mosquito   404 QRALYSTVRSTDTAMVVRDTMLSESIETRFLVPGDVLEIPAT--GCTMQCDAVLLSGNCILDESM 466

  Fly   358 LTGESVPLMKESLESLDNLDVEMDAEGDGKLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRT 422
            |||||||:.|..|....:|   :....:.....||.||:|:|......|.:       :..|:.|
Mosquito   467 LTGESVPVTKTPLPLRRDL---IYNRKEHARHTLFCGTRVIQTRYIGSEKV-------LVKVLNT 521

  Fly   423 GFNTSQGKLLRTILFGANRATENNVETFAFIAFLMVFAVAAASY-VWVKGSEDPERNRYKLFLEC 486
            |..|::|.|:|:||:......:...:::.||..|.:.|.....| ::.|.|.  .....|:.:|.
Mosquito   522 GNITAKGGLVRSILYPPPVDYKFEKDSYKFITVLGIVAFCGFVYTLYTKISR--SIGAVKIIVES 584

  Fly   487 TLILTSIIPPDLPIELTLAVNTSLIQLTKLFVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVE 551
            ..::|..:||.||..:|:....:..:|.:..::|..|..|..:|.:...|||||||||.|.|.:.
Mosquito   585 LDLITIAVPPALPAAMTVGRMYAQKRLKRSNIYCISPRAINVSGSIDCVCFDKTGTLTEDGLDMW 649

  Fly   552 GIAGLAPNGACVPIEKAEGNTVQV-----------------LACCHSLALLDDGLVGDPLEKATL 599
            |:           :.|...|:.|:                 :..|||:..::..:.||||:....
Mosquito   650 GV-----------LPKDSTNSFQIPLKDVGRLPMSDHLLFGMVTCHSITFVNGEMRGDPLDLKIF 703

  Fly   600 AAVDWTL--------TKMDSVIP---KRPQ-----------------FKPLKIIQRYHFSSALKR 636
            .:..|.|        ||.|.:.|   |.|:                 ...:.|::.:.|:|||:|
Mosquito   704 ESTGWILEEANVSDETKYDMLFPTIVKPPRGDSRDELNLELDVAYDNSNDIGIVREFSFTSALQR 768

  Fly   637 MSVLA-----GHLIPYSNEVKHIGAVKGAPEVIQKMLR--EVPADYEKVYLEYARRGARVLALGI 694
            |||:.     .|...|         |||:||:|..:.|  .:|.|::.....||.:|.|::|:..
Mosquito   769 MSVVTRKVSDNHFNVY---------VKGSPEMISSLCRPESIPEDFQSKLGFYAHQGYRIIAIAY 824

  Fly   695 KDLG-TLGAQRVREMKREEVECDLTFAGFLIISCPMKPDSKSVIKELIQSSHKVVMITGDSPLTA 758
            |.|. .|...:|:::.||:|||:|.|.||:|:...:|.|::.||:.|..::.:.||:|||:.|||
Mosquito   825 KQLDKKLNYPKVQKIAREKVECELEFLGFVILENRLKTDTEEVIESLNAANIRSVMVTGDNLLTA 889

  Fly   759 CHVARE--LRFTRKKLIILTPPEE----DR----------------------------------- 782
            ..||.:  :....:.|:.:|...:    ||
Mosquito   890 ASVAHDCGMILAGQNLVTVTAHADKANPDRYFLSYDITGQPQLTQSDIMNDNQVDGSVGGKPDGP 954

  Fly   783 ---KNNWSWV----------SID--------GDQSYELDTKPGSKKLSHLLATHDL--------- 817
               |.|.::|          |||        .|:.:.:..:|.|....|.||| |:
Mosquito   955 VRAKENGNYVPMTESNSISSSIDTCTITTQLSDKEHRIVIEPASDHDCHSLAT-DIGSIKVVANG 1018

  Fly   818 ---------------CITGEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLGYCT 867
                           .:||:....:.::.|:.:..:....||.||.:|.||:.:||.|:||||..
Mosquito  1019 VPGKLGPGGGSSFRFALTGKTWAIINEHFPELVSTITTYGTVFARMSPDQKQHLITGLQQLGYYV 1083

  Fly   868 LMCGDGTNDVGALKHANVGVSLLTSAPVKRKRTEEEQQQAAANAAAIAAQAQANANQQLTTRERA 932
            .|||||.||.||||.|:.|:||          :|.|
Mosquito  1084 AMCGDGANDCGALKAAHTGISL----------SEAE----------------------------- 1109

  Fly   933 LRRRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTLVTTLQ 997
                                            :|:|:|||||:.:|.||.::||:||..|||:..
Mosquito  1110 --------------------------------SSVASPFTSKNPTIACVPNVIKEGRAALVTSFG 1142

  Fly   998 MFKILALNALIQAYCQSVLYIDGIKFSDTQATMQGIFIAACFLF-----------ITRAKPLKTL 1051
            :||.:|..:|:|.....:||......:|.|.....:||.:...|           :.:..|..:|
Mosquito  1143 IFKFMAAYSLVQFASVVILYSIDSNLTDWQYLYIDLFIISIVAFFFGKTSSYDGPLVKQTPSNSL 1207

  Fly  1052 SKVAPLPNIFNFYTISTILSQFAVHFGTL--YYLTSQANILAPPREGKVKLYIDMDAEEKTKYDP 1114
            ..:|||.::             |:|....  ..|....::.|.|.........|.:..:...::
Mosquito  1208 ISLAPLLSL-------------ALHMMVAIGMQLAGWYHVQAQPWFEPFNYTSDRELNDHGCFE- 1258

  Fly  1115 NIVSSTVYII-CLSLQVATIAVNYKGYPFMESLRSNRMLMYAIGASAALVILLSTGLAPELTEFF 1178
               :.|::.| |....:..|..: ||.|:.:|:.||...:.:|..:.|:.|:|:......:.|.|
Mosquito  1259 ---NYTIFAISCYQYLILAIVFS-KGAPYRKSIFSNYGFIISILVNVAIAIVLTVYPPAWIAEQF 1319

  Fly  1179 EIIDFPTD----FRKTLLGVLVLDIVGAFLLDRICSFLFGET 1216
            |:: .|.|    ||..|:...:::    |||.     :|.||
Mosquito  1320 ELV-MPPDGEFRFRLYLVAYGLIN----FLLS-----MFIET 1351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-type_ATPase_cation	220..1152	CDD:319843	277/1095 (25%)
anne	XP_061510158.1	None