Protein Alignment CG6230 and atp13a5l.2

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: XP_004914422.3
• Gene: atp13a5l.2 / 101733684
• XenbaseID: XB-GENE-22167922
• Length: 1193
• Species: Xenopus tropicalis
• Alignment Length: 1239
• Identity: 324/1239 - (26%)
• Similarity: 537/1239 - (43%)
• Gaps: 249/1239 - (20%)

  Fly   106 VGFIGVLAIAFLHILTLLFCYWSVHVLAFLTCRRVKLPGANVL-------------AKV------ 151
            :|:|  .::.||.:|    .||...:..:..|....|..|:|:             .||
 Frog    33 IGYI--FSLGFLRVL----FYWKPELDVWCQCIPCSLSEADVILLRTTDELKQYYKKKVNEIYPC 91

  Fly   152 VPTPNNGNSKI-----VPIRSSKLEDGSTQYYFVFQKTKYVWNEDRKTFRAVE--FPVNGLLSTY 209
            :|...:.:..|     :..||.....|..:|..| ||.:|.||       .||  |..||:|...
 Frog    92 IPGSKSSHQIITGENSIMSRSLIKPQGKIRYIEV-QKIRYAWN-------TVEGQFQKNGILEEE 148

  Fly   210 SSSRGLE-------TEEDIKRATQTYGNNEMEMVVPEFHELFIERATAPFFVFQVFSVGLWCMDD 267
            .|...:.       |:|:.:...|..|.|::|:.:.....|.......||::||.:|:.:|....
 Frog   149 LSCSDIHSKFGSGLTQEEQEFRQQVCGLNKIEVEIKPLWVLLFTDIFNPFYIFQAYSLSVWATSG 213

  Fly   268 YWYYSLFTLFMLIAFECTIVKQQLRNMSEIRKM--GNKPYLIYAFRQN-KWRHLGSDELLPGDLV 329
            |:|.....|.|.|...|..:....:...::.||  .....::...|:| :.:.:.|..|:|||::
 Frog   214 YFYNGGIILSMTILSICATLYNLRKQSVKLHKMALSYNSVMVTVLRKNGEVKEVESQSLVPGDVI 278

  Fly   330 SITRSQNDNIVPCDLVILRGSCIVDESMLTGESVPLMKESLESLD-NLDVEMDAEGDGKLFVLFG 393
            .||.|:  ..:|||.|::.|||.::|.||||||:|:.|.:|.:.: .:..::....|.|..|||.
 Frog   279 IITGSK--LFLPCDAVLISGSCTINEGMLTGESIPITKNALPNTEGTVPWKLQCGEDYKRHVLFC 341

  Fly   394 GTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENNVETFAFIAFLMV 458
            ||:|:|..|...:.::|       .|::|||||::|.|:|.||:........:.|...||..|:.
 Frog   342 GTEVIQTKAHGLDLVKA-------VVLQTGFNTAKGDLVRAILYNKPVNVRLHKEAIRFIFVLVG 399

  Fly   459 FAVAAASYVWV-------KGSEDPERNRYKLFLECTLILTSIIPPDLPIELTLAVNTSLIQLTKL 516
            .|.....|..|       ..|:...|:.:        :||:.:...||..||:.:..:..:|.||
 Frog   400 IASCGVIYTAVIYTINGASVSQTVVRSLH--------LLTAAVNAALPASLTIGLLNAQKRLKKL 456

  Fly   517 FVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVEGIAGLAPNGACVPIEKAEGNTVQ------- 574
            .:||..|.||..||::.:.|||||||||.|:|   .:.|:.|         ::||:.|
 Frog   457 GIFCIRPQRINIAGQLNLVCFDKTGTLTEDSL---DLCGVVP---------SDGNSFQDIHLFTS 509

  Fly   575 -----------VLACCHSLALLDDGLVGDPLEKATLAAVDWTLTK------------MDSVIPKR 616
                       .:|.||||.:||..:.||||:........|.|..            ..:|:...
 Frog   510 GETLPWGPVLGAMASCHSLIMLDGEIQGDPLDIKMFEGTGWELENHSKHGTEESGSISSTVVKPG 574

  Fly   617 PQ-----FKPLKIIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGAVKGAPEVIQKMLRE--VPAD 674
            |:     .:.:.|:.::.|||:|:||||:|    ..:.|......:|||||::.|..::  ||.:
 Frog   575 PRAGKVPVEGIAILHQFPFSSSLQRMSVVA----QITGESGLTVFMKGAPEMVVKFCKQETVPLN 635

  Fly   675 YEKVYLEYARRGARVLALGIKDLGTLGAQRVREMKREEVECDLTFAGFLIISCPMKPDSKSVIKE 739
            ..|....|..:|.|||.||.:.|.....|.::.::||.||.|:.|.|.||:...:||:::.|::|
 Frog   636 LSKKLEFYTTQGFRVLGLGYRLLEKESLQIIQHLERETVEKDIIFLGLLILENNLKPETRGVLQE 700

  Fly   740 LIQSSHKVVMITGDSPLTACHVARELRFTRKKLIILT----PPEEDRKNNWSWVSIDGDQSYELD 800
            |.::..:.||||||:..||.|:........|...|:|    .|:.|.....:|.::  .:::|..
 Frog   701 LTEAKIRSVMITGDNLQTALHIGVTCGMIPKSSKIITIEAKEPQNDSPAAITWKTM--TETHENG 763

  Fly   801 TKPG------SKKLSH----LLATHDLCITGEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKEL 855
            .|..      |.|..|    ..|.| ....|:..|.|.|:....:.::|...|:.||..|:||.:
 Frog   764 HKESGSHFDISDKWDHNSFSTEAFH-FATDGKSFQILLQHFYNLVPKILQNGTIFARMTPRQKSV 827

  Fly   856 VITQLKQLGYCTLMCGDGTNDVGALKHANVGVSLLTSAPVKRKRTEEEQQQAAANAAAIAAQAQA 920
            :|.:.::|.||..|||||.||.||||.|:||:|:
 Frog   828 LIEEFQKLDYCVGMCGDGANDCGALKMASVGISV------------------------------- 861

  Fly   921 NANQQLTTRERALRRRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHII 985
               .||                                     :||:|:|||||..:|.||..:|
 Frog   862 ---SQL-------------------------------------EASVASPFTSKIPNISCVPLLI 886

  Fly   986 KQGRCTLVTTLQMFKILALNALIQAYCQSVLYIDGIKFSDTQATMQGIFIAACFLFITRAK-PLK 1049
            |:||.:|||:..|||.|.:..:::.....:|:.......:....:|.|.:.....||.... |..
 Frog   887 KEGRNSLVTSFFMFKFLTMITVVELTSLGILFWKQKIIGEWHYLLQDIALTLPITFIGSLNGPAP 951

  Fly  1050 TLSKVAPLPNIFNFYTISTILSQFAVHFGTLYYLTSQANILAPPR----EGKVK---LYIDMDAE 1107
            .|:...|..:|.:    ..:|...::||.....|...|.:|...:    |..|.   |.::.::.
 Frog   952 KLAPYRPSGHIMS----PPLLLSVSLHFLFTIILQVTAFVLLQQQPWYNESDVVSACLPLNQNSG 1012

  Fly  1108 EKTKYDPNI---VSSTVYIICLSLQVATIA-VNYKGYPFMESLRSNRMLMYAIGASAALVILLST 1168
            ..|..:|::   ..:|:..|..|:.:.|:. |..||.||.:|:.:|.:|:..:....|:.|.|..
 Frog  1013 NVTMREPSMSVNYLTTMEWIVTSMNIITLEFVLCKGQPFRKSIYTNYLLVLLLTIHVAVYIFLLF 1077

  Fly  1169 GLAPELTEFFEIIDFPTDFRKTLLGVLVLDIVGAF--------------LLDRICSFLFGETRRK 1219
            .....:...||.:..|..:|..:..:|::..|.::              |:.|:|.:   |::.:
 Frog  1078 ADIESIYLLFEAVCTPYYWRVYIFVMLLVHFVISYAVEEGILENKKLWILIKRLCKY---ESKSQ 1139

  Fly  1220 SKVL 1223
            .|.|
 Frog  1140 YKRL 1143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	315/1190 (26%)
		E1-E2_ATPase	310..515	CDD:278548	65/213 (31%)
		Cation_ATPase	<590..664	CDD:289987	24/90 (27%)
		COG4087	<850..901	CDD:226572	22/50 (44%)
atp13a5l.2	XP_004914422.3	P5-ATPase	12..133	CDD:403569	23/106 (22%)
		P-type_ATPase_cation	165..995	CDD:319842	259/940 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D172453at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010