Protein Alignment CG6230 and atp13a4

DIOPT Version :9

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: NP_001186977.1
• Gene: atp13a4 / 100498523
• XenbaseID: XB-GENE-978090
• Length: 1203
• Species: Xenopus tropicalis
• Alignment Length: 1293
• Identity: 333/1293 - (25%)
• Similarity: 562/1293 - (43%)
• Gaps: 264/1293 - (20%)

  Fly    15 GDAESYGKEMALQSGRPKEPTKLDDLVQYVSLHVRIPTPLTGVVLPFVPLYLSAFYLWINVTGGQ 79
            |:|...|.:..|..|...|.    |:..|       .|.:...||..:....|..:||:......
 Frog     2 GEAHKDGHKALLNPGEENEM----DIFGY-------KTHICRKVLCIIGYIFSLGFLWLLFYWKP 55

  Fly    80 ENDTTNNDVITADNQT------TTDNI--TTWNDVGFIGVLAIAFLHILTLLFCYWSVHVLAFLT 136
            |.....|.|..:..:.      |||:.  |:|..|.:|                  .:....|.|
 Frog    56 EWHVWANCVPCSLEEASVVLLRTTDDFKQTSWKKVKWI------------------QLSSKDFKT 102

  Fly   137 CRRVKLPGANVLAKVVPTPNNGNSKIVPIRSSKLEDGSTQYYFVFQKTKYVWNEDRKTFRAV--- 198
            .|.......:.:.|.:..|.      :.:|           |...||.:|:|:...|.|...
 Frog   103 YRAATKDPDSTINKAIIMPE------LKVR-----------YVQVQKIRYIWDNIEKQFTKAGIL 150

  Fly   199 --EFPVNGLLSTYSSSRGLETEEDIKRATQTYGNNEMEMVVPEFHELFIERATAPFFVFQVFSVG 261
              .:..:.:.:.:.|...|| ||.|:|.  ..|.|.:::.:....:|.::....||:|||:|||.
 Frog   151 EDHYSCSSIHAMFESGVALE-EEGIRRL--ICGPNIIDVGIIPIWKLLVKEVLNPFYVFQLFSVC 212

  Fly   262 LWCMDDYWYYS----LFTLFMLIAFECTIVKQQLRNMSEIRKMGNKPYLIYAFRQNKWRHLGSDE 322
            ||..:.|..||    |.:|..:.....|:.:|.::....:....|....:|...:..: .|.|..
 Frog   213 LWFAEKYIEYSVAIILMSLICIFLSVYTLRQQSVKLHKLVESHNNITVSVYGEDRGIF-DLESRH 276

  Fly   323 LLPGDLVSITRSQNDNIVPCDLVILRGSCIVDESMLTGESVPLMKESLESLDNLDV-EMDAEGDG 386
            |.|||::.|.|   :.::|||.::.:|.|||:||||||||:|:.|..|.:.||.:. ::.:..|.
 Frog   277 LAPGDILVIKR---NTLLPCDALLFKGGCIVNESMLTGESIPVTKTPLPNTDNTEPWKVHSVHDY 338

  Fly   387 KLFVLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILF--GANRATENNVET 449
            |..|||.||:|:|..|.....::|       .|:||||||::|.|:|:||:  ..|.....:...
 Frog   339 KRHVLFCGTQVIQVKASYNSPVKA-------VVLRTGFNTAKGDLVRSILYPKPVNYRLYRDAVI 396

  Fly   450 F-------AFIAFLMVFAVAAASYVWVKGSEDPERNRYKLFLECTLILTSIIPPDLPIELTLAVN 507
            |       |||.  |::|:...|   :.||...|     :.|:...::|..:||.||..||..:.
 Frog   397 FLCTLIGTAFIG--MIYAICVFS---LSGSAPGE-----VVLKALDVITIAVPPALPAALTAGIM 451

  Fly   508 TSLIQLTKLFVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVEGIAG-----------LAPNGA 561
            .:..:|.|..:||..|.||...|.:.:.|||||||||.|.|.:.|:..           |:|:.:
 Frog   452 YAQRRLEKAGIFCISPQRINLCGMINLFCFDKTGTLTEDGLDLWGVVPANGYRFQNVIILSPDSS 516

  Fly   562 CVPIEKAEGNTVQVLACCHSLALLDDGLVGDPLEKATLAAVDWTL--TKMDSVIPKRPQ--FKP- 621
             :|    .|.....:|.||||.:||..:.||||::....:..|.|  .:.|::....||  .||
 Frog   517 -LP----WGPLFGAMATCHSLIVLDGNVQGDPLDQKMFESTCWVLEDQQEDNMTENMPQRIVKPG 576

  Fly   622 ----------LKIIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGAVKGAPEVIQKMLR--EVPAD 674
                      :.|:|::.|||:|:||||:...|    |..::...:|||||::....:  .||.:
 Frog   577 PTTSSDVIEGIVILQQFPFSSSLQRMSVITQVL----NGDEYAVYLKGAPEMVASFCKTDTVPIN 637

  Fly   675 YEKVYLEYARRGARVLALGIKDLGTLGAQRVREMKREEVECDLTFAGFLIISCPMKPDSKSVIKE 739
            :......|.::|.||:.|..|.|.....:::..:||||||.||.|.|.|::...:|.:::.|:||
 Frog   638 FPDELAFYTKQGFRVIGLAYKILDIKDHKKLLTLKREEVESDLIFLGLLVLENRLKLETRPVLKE 702

  Fly   740 LIQSSHKVVMITGDSPLTACHVAREL-RFTRKKLIILTPPEEDRKNNW---SWVSIDGDQSYELD 800
            |.::..:.||||||:..||..||:.. ..:....:||...:|...::.   :|..:||.:|...|
 Frog   703 LNRAKVRSVMITGDNLQTAVTVAKNSGMISEGSNVILIEAKEPSGSDLATITWTLVDGIKSKNYD 767

  Fly   801 -----------TKPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKE 854
                       :||..:.|.:..|     :.|...|.:.|:....::::|...|:.||.:|.||.
 Frog   768 FMDICISMEEVSKPAEENLHYHFA-----MNGSTYQVIIQHFNNLLQKILIHGTIFARMSPGQKS 827

  Fly   855 LVITQLKQLGYCTLMCGDGTNDVGALKHANVGVSLLTSAPVKRKRTEEEQQQAAANAAAIAAQAQ 919
            .::.:.::|||...|||||.||.||||.|:||:||          :|:|
 Frog   828 NLVEEFQKLGYSVGMCGDGANDCGALKMAHVGISL----------SEQE---------------- 866

  Fly   920 ANANQQLTTRERALRRRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHI 984
                                                         ||:|:||||.:.:|.||..:
 Frog   867 ---------------------------------------------ASVASPFTSNTPNIECVPRL 886

  Fly   985 IKQGRCTLVTTLQMFKILALNALIQAYCQSVLYIDGIKFSDTQATMQGIFIAACF---LFITRAK 1046
            ||:||..|||:..:||.:||.::||.....:||.:...:::.|...|.:.|....   :.:..|.
 Frog   887 IKEGRAALVTSFCVFKYMALYSMIQYIGVLLLYWEKTTYANYQFLFQDLAITTVISVTMSLNHAY 951

  Fly  1047 P-LKTLSKVAPL--PNIFNFYTISTILS------QFAVHFGTLYYLTSQANILA---PPREGKVK 1099
            | |.:....|.|  |.:.....|:.|||      .|.:.....:|::..::|.:   |..:
 Frog   952 PRLSSFKPPAQLISPPLLLSVLINIILSLILQVCGFVIVQKQQWYISDLSSIYSACVPTNQ---- 1012

  Fly  1100 LYIDMDAEEKTKYDPNIVSS---------------TVYIIC-LSLQVATIAVNYKGYPFMESLRS 1148
               .:........|.|:.:|               |::::. |:..:..:.|: ||.||.:.:.:
 Frog  1013 ---SLSTSRPVSNDTNLTTSANSAEISDFQSYENTTIWLLATLNCLIVALVVS-KGKPFRQPIYT 1073

  Fly  1149 NRMLMYAIGASAALVILLSTGLAPELTEFFEIIDFPTDFRKTLLGVLVLDIVGAFLLD 1206
            |.:.:..|....|:.:.........|.:..:::..|..:|..:|.:|::.:..:::.:
 Frog  1074 NYIFILVIAVQFAVCLFFLFADIQNLYKALDLVCTPLIWRGAILIMLLITLAVSYIAE 1131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	308/1176 (26%)
		E1-E2_ATPase	310..515	CDD:278548	71/214 (33%)
		Cation_ATPase	<590..664	CDD:289987	28/88 (32%)
		COG4087	<850..901	CDD:226572	22/50 (44%)
atp13a4	NP_001186977.1	P5-ATPase	17..133	CDD:289194	27/161 (17%)
		P-ATPase-V	18..1119	CDD:273738	327/1263 (26%)
		Cation_ATPase_N	<164..214	CDD:279080	18/52 (35%)
		E1-E2_ATPase	224..467	CDD:278548	80/263 (30%)
		Cation_ATPase	<589..631	CDD:289987	17/45 (38%)
		COG4087	<817..>866	CDD:226572	25/58 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54176
OrthoDB	1	1.010	-	-		D172453at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.930