Protein Alignment CG6230 and LOC100494846

DIOPT Version :10

• Sequence 1: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Sequence 2: XP_002932273.2
• Gene: LOC100494846 / 100494846
• XenbaseID: XB-GENE-29082435
• Length: 1189
• Species: Xenopus tropicalis
• Alignment Length: 1192
• Identity: 305/1192 - (25%)
• Similarity: 510/1192 - (42%)
• Gaps: 264/1192 - (22%)

  Fly   101 TTWNDVGFIGVLAIAFLHILTLLFCYWSVHVLAFLTCRRVKLPGANVL-------------AKVV 152
            |.|.......|..|..|..|.||| ||...:..:..|...:|..|:|:             .||:
 Frog    23 TVWWRQALCVVGHIISLGFLQLLF-YWRPELDVWCRCAPCRLMEADVVLIRTTDEHREYSKRKVL 86

  Fly   153 P-TPNNGNSKIVPIRS---------SKL--EDGSTQYYFVFQKTKYVWNEDRKTFRAV-----EF 200
            . :|..|.||  |:..         |||  |......|...||.:|.||.....|:.:     |.
 Frog    87 EISPCTGGSK--PVHQIVTEKNSIISKLITEPEGRMRYMEVQKIRYAWNTVEGKFQRIGVLDEEL 149

  Fly   201 PVNGLLSTYSSSRGLETEE-DIKRATQTYGNNEMEMVVPEFHELFIERATAPFFVFQVFSVGLWC 264
            ....:.|.:.|  ||..|: :|::  :..|.|.:|:.:.....|..:....||:|||.:|:.||.
 Frog   150 SCLDIYSKFGS--GLSPEDREIRQ--RVCGPNSIEVKIKPVWVLLFKEIFNPFYVFQAYSICLWL 210

  Fly   265 MDDYWYYSLFTLFM-LIAFECTIVKQQLRNMSEIRKMG---NKPYLIYAFRQNKWRHLGSDELLP 325
            .::|..|:...|.| |::...||...:.::: ::.||.   |...:....:..:.:.:.:..|:|
 Frog   211 SNNYVEYACAILAMTLVSVAATIYNLRAQSV-KLHKMSISFNSIMVTVLHKNGELKEVEAQSLVP 274

  Fly   326 GDLVSITRSQNDNIVPCDLVILRGSCIVDESMLTGESVPLMKESLE-SLDNLDVEMDAEGDGKLF 389
            ||::.:  ::.:..:|||.:::.|.|.|:|.||||||||:.|..|. |..::..:..:..|.|..
 Frog   275 GDVIVL--AETNRSLPCDAILISGGCTVNEGMLTGESVPVTKIPLPCSEGSVPWKTQSGDDYKKH 337

  Fly   390 VLFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENNVETFAFIA 454
            |||.|::::|..|.::|.::|       .|::|||||::|.||::||:..:...:.:.:....:.
 Frog   338 VLFCGSELIQTKAQSQELVKA-------VVLQTGFNTTKGDLLKSILYNKSINVKLHRQAMYVVL 395

  Fly   455 FLMVFAVAAASYVWVKGSEDPERNRYKLFLECTLILTSIIPPDLPIELTLAVNTSLIQLTKLFVF 519
            .|:||.:..|.|..|..:. .|.:.....|.|.::|:..:...||..|||.:..:..:|.||.:|
 Frog   396 ILVVFTLGEAVYTAVIFTY-YEASVQDTVLMCLIVLSVAVNAALPASLTLGLLYAQTRLKKLGIF 459

  Fly   520 CTEPFRIPFAGKVQICCFDKTGTLTTDNLMVEGIAGLA----------PNGACVPIEKAEGNTVQ 574
            |..|.||..||::.:.|||||||||.|.|.:.|:...:          ..|..:|    .|..:.
 Frog   460 CISPQRINLAGQLNLFCFDKTGTLTEDFLDLHGVVPFSGGSFQDIHFFTTGKTLP----WGPLLG 520

  Fly   575 VLACCHSLALLDDGLVGDPLEKATLAAVDW------------------TLTKMDSVIPKRPQFKP 621
            .:..||||.:|:..::||||:........|                  ||.|..:...:.| .:.
 Frog   521 AMTSCHSLIMLNGKMLGDPLDVKMFEGTGWEFKSHAAHRTKDGELISCTLVKPAAGAGEDP-VEG 584

  Fly   622 LKIIQRYHFSSALKRMSVLAGHLIPYSNEVKHIGA------VKGAPEVIQKMLR--EVPADYEKV 678
            :.|:.::.|||:||||||:          .:.||.      |||||||:.::.:  .||.:..:.
 Frog   585 IAILHQFPFSSSLKRMSVI----------TQIIGERDLTVFVKGAPEVVIELCKPGTVPPNVSEK 639

  Fly   679 YLEYARRGARVLALGIKDLGTLGAQRVREMKREEVECDLTFAGFLIISCPMKPDSKSVIKELIQS 743
            ...|..:|.||:.|..:.........:..::|:.:|.||.|.|.||:...:||::.||::||..:
 Frog   640 LDYYTTQGFRVIGLAYRLFMNESLPDLHHIERDMIETDLIFLGLLILENRLKPETISVLQELAAA 704

  Fly   744 SHKVVMITGDSPLTACHVARELRFTRK--KLIILTPPE-----------------EDRKNNWSWV 789
            :.:.||||||:..||.::........|  |||::...|                 |:.|:..|.:
 Frog   705 NIRNVMITGDNLQTALNIGTNCGMIPKSSKLILVEANEPQKHVPASITWKTIIQNEENKHKESIL 769

  Fly   790 SIDGDQSYELDTKPGSKKLSHLLATHDLCITGEGLQYLQQNQPQYMRQLLPQI----TVCARFAP 850
            .|:.:..:..:|....|        :...:.|:..:.|.    |:...|:|::    |:.||..|
 Frog   770 PINMNDGWNHNTFQPVK--------YHFAMDGKAFEILL----QHFYNLVPKVLLNGTIFARMTP 822

  Fly   851 KQKELVITQLKQLGYCTLMCGDGTNDVGALKHANVGVSLLTSAPVKRKRTEEEQQQAAANAAAIA 915
            :||..:|.:.:::.|...|||||.||.||||.||||:||
 Frog   823 RQKSSLIEEFQKIDYHVGMCGDGANDCGALKMANVGISL-------------------------- 861

  Fly   916 AQAQANANQQLTTRERALRRRQEHLNQTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSSIMC 980
                    .:|                                     :||:|:||||...:|.|
 Frog   862 --------SEL-------------------------------------EASVASPFTSNIPNIKC 881

  Fly   981 VNHIIKQGRCTLVTTLQMFKILALNALIQAYCQSVLYIDGIKFSDTQATMQGIFIAACFLFITRA 1045
            |..:||:||..||::..:||.|.:..|:......:|::......:.|.|:|.|.|...|..
 Frog   882 VTTLIKEGRNALVSSFTVFKFLTMVTLLALTSFVLLFLKQALLGNIQFTLQDIGIMVVFSL---- 942

  Fly  1046 KPLKTLSKVAPLPNIFNFYTISTILSQFAVHFGTLYYLTSQANILAPPREGKVKLYIDMDAEEKT 1110
                |.|...|.|.:..:.....:||...:...||:.|              :.:.:::.|....
 Frog   943 ----TASLNGPAPKLAPYRPPGQLLSPSLLLSVTLHCL--------------LNIALEVTAFLLL 989

  Fly  1111 KYDPNIVSSTVYIICLSLQ-------------------VATI----AVNY--------KGYPFME 1144
            :..|.|..|.|...|..|.                   |.|:    ::||        ||.||.:
 Frog   990 QQQPWINESDVISACQPLNHSTGNVTTTEVASASAASLVTTVFFISSMNYIVLEFVFSKGRPFRK 1054

  Fly  1145 SLRSNRMLMYAIGASAALVILL 1166
            .|.:|.:|.:.:....|:::.|
 Frog  1055 RLHTNYLLSFMMVLQVAVLLFL 1076

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6230	NP_609490.1	P-type_ATPase_cation	220..1152	CDD:319843	263/1026 (26%)
LOC100494846	XP_002932273.2	P5-ATPase	12..133	CDD:463565	30/112 (27%)
		Haloacid Dehalogenase-like Hydrolases	165..994	CDD:473868	248/961 (26%)