Protein Alignment Idua and idua

DIOPT Version :10

• Sequence 1: NP_609489.1
• Gene: Idua / 34544
• FlyBaseID: FBgn0032343
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_001923689.3
• Gene: idua / 567720
• ZFINID: ZDB-GENE-060526-29
• Length: 637
• Species: Danio rerio
• Alignment Length: 648
• Identity: 185/648 - (28%)
• Similarity: 290/648 - (44%)
• Gaps: 96/648 - (14%)

  Fly    28 MPHFWTGVGFCPAGRIDHEGISAALGD--PALRLNLRLIAALPVGAVTHIRIHWLLELIQFWQYD 90
            :.|||...||||    ......|.|.|  |..::||.||.::|...:..:||||:|||:....|
Zfish    44 LEHFWRSTGFCP----PQPHTDAHLYDLSPDQQMNLALIGSVPHRGIQQVRIHWMLELVSARVY- 103

  Fly    91 PSGIPIYDFSKFDDFIDFLHEELRLSPVLEWMGNLGGVFSE-NPMQQSFYWEHLVKTTINHQIAR 154
             .|...|:|:..|..||.|.:. .|.|..|.||::...||. ...||...|.:||.......|.:
Zfish   104 -GGEYHYNFTHLDQLIDLLWQN-GLQPGFELMGSVSNTFSNFEDKQQITEWRNLVYLIAKRYIWK 166

  Fly   155 HGSSRLVNWRYETWNEPDLRGYNKQNFTAHTFLDYVQAVRRGLSKAGNLDNQDGKVPLPMYRSLR 219
            :|...:..|.:||||||:...::....:...||:|..|...||..|.           |:.: ..
Zfish   167 YGLGFVSQWNFETWNEPNNHDFDNITVSIQGFLNYYDACSEGLRAAS-----------PLLK-FG 219

  Fly   220 GPAGLFKDSNH-----PLCWNLLELCSQRVVY------CPIDILTFHRKGIEGTATEIVNGSLSL 273
            ||.    ||.|     |.||.:|:.|.....|      ..:|.:..|:|| .|.:..|:...:|.
Zfish   220 GPG----DSCHSQPRSPYCWEMLKHCYNGTNYFTGESGVRLDYIALHKKG-GGGSLPILQQEVST 279

  Fly   274 MAKIYEEYPNLKQLPVANDEADPVAGWSTSRDFQADVRYGITLISTVMQFWHAKLAG-GPLSRLE 337
            :.:|.:.:|:...||:.||||||:.||:....::|||.|...::..:.|.....:|. .......
Zfish   280 VQEIQQLFPDFCSLPIYNDEADPLVGWNKPLTWRADVTYAAMVLKVISQHQDLLIADRNSTVNYT 344

  Fly   338 SISHDNAFLSYHPHEFTQRTLLAHFRMNETKPPHSQLVQKPVYAALGMLAKLGTRAADVEMVNMD 402
            .:|:||||||||||.|:||||.|.|::|.|.|||.|:::|||...:|:||.||......|:  .|
Zfish   345 LLSNDNAFLSYHPHPFSQRTLTARFQINSTNPPHVQILRKPVLTVMGLLALLGETQVQAEV--SD 407

  Fly   403 TKHSVQVLRTVSGGLGGPGQYMATIFLSPEEAGPKMTAFHHKYTLNMSIANESA----------- 456
            ...||.:|.:|         ::..:..|.:.....:..::.:.  |.:..::..
Zfish   408 VNASVGLLASV---------HVPQVPFSADSWQSSVLIYNSRD--NQTSTSDDVISLRITGLPQR 461

  Fly   457 ----FVTELLVPKETDPYYIWQQAGSPAYPNATLREAMRRAQAPRLYKTGPIWQYNSELVINSAS 517
                :||..:....|:|:.:|:....|.||.|.....||..:.|:  ..||:...:...::...|
Zfish   462 QGLMYVTHYMDNNVTNPFKLWESMSRPDYPTAQQFTQMRNQEDPQ--TDGPLPVPSDGSLMLKKS 524

  Fly   518 IPLPWAMLLRVCSASWPKLRRPQQLSIAEVTQREVFISWMEHPKSTQCLLSYEVWF--------- 573
            :|:|..:|:.:|:.|.....:...|....:|:.:|.|.|.:|...|:|:.:|||.|
Zfish   525 LPIPSVLLVHICAQSEEMPNQVNGLRFISITKGQVLIIWKDHCVGTKCIKTYEVEFSRDESTFLR 589

  Fly   574 -KERDNLGRSADWMLISQGWHLPYPSFQYAPGDKGSVNGFYKVRGVDVFNETSPYSQIVEYLE 635
             ..||.:                :..|.|:| :...|:|||:.|.||.:.....||...||.|
Zfish   590 INHRDTI----------------FTYFTYSP-ESLEVSGFYRARAVDYWGRNGEYSVTEEYSE 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idua	NP_609489.1	Glycosyl hydrolases	31..497	CDD:474034	146/495 (29%)
idua	XP_001923689.3	Glycosyl hydrolases	31..519	CDD:474034	150/513 (29%)