Protein Alignment Reps and END3

DIOPT Version :10

• Sequence 1: NP_609487.2
• Gene: Reps / 34542
• FlyBaseID: FBgn0032341
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_014315.1
• Gene: END3 / 855640
• SGDID: S000005028
• Length: 349
• Species: Saccharomyces cerevisiae
• Alignment Length: 289
• Identity: 63/289 - (21%)
• Similarity: 97/289 - (33%)
• Gaps: 93/289 - (32%)

  Fly   297 SRIPVEELRHIWQLCDVTRDGALSLSEFTAAMHLV--VLRRNNIPLPTSLPHCLHPNVLQAAASG 359
            |::....|..||.|.|:..|..|...||...|.|:  ::.:|...:|..||..|.|        |
Yeast    38 SKLDSSVLNKIWFLADIDDDDNLDFEEFVICMRLIFDMVNKNISSVPDELPDWLIP--------G 94

  Fly   360 SGQGVTSSSSAALPQE----PPEADL---LHLNDDDEDDH----------TDNTIIAGNLSGSST 407
            |...:..........|    ||:.::   .:::.||.:.:          ||.||....||...:
Yeast    95 SKVNLIKERKKRKQIENADLPPKKEIKVDWYMSPDDLNQYEKIYNSCAKLTDGTITFNELSTKLS 159

  Fly   408 TS----------------KPRPNVPS-DKN-----------------------------IMNLSS 426
            |.                .|: |:|| |::                             :.|...
Yeast   160 TKFFNISKTDLNKVWSLINPQ-NLPSIDRDPTFYFIHCLRQRNDLGAEIPASLPNSLAEVCNKKQ 223

  Fly   427 IS---TSSQASNSSKREATPQNSL---GKNRSI-SNSPNVEKPVSGTVSSTASAVDS--TNVSSQ 482
            :|   .|||.....|.||...::|   |:|.|. |:..||...........||..|.  .|:..|
Yeast   224 LSYDLRSSQPPTKRKEEANEVDNLRDNGQNSSSDSSGSNVLSNEDSIKQKYASLTDDQVANMREQ 288

  Fly   483 WT-----KFSE-----SPTTSAVSVQSTT 501
            ..     |.||     |..:..::::|.|
Yeast   289 LEGLLNYKKSEKTQGGSKLSKRINIRSIT 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reps	NP_609487.2	EH	262..345	CDD:197477	14/49 (29%)
END3	NP_014315.1	EF-hand_4	1..104	CDD:289529	20/73 (27%)
		EH	123..221	CDD:197477	14/98 (14%)
		End3	186..345	CDD:432765	27/132 (20%)