Protein Alignment Reps and Reps

DIOPT Version :10

• Sequence 1: NP_609487.2
• Gene: Reps / 34542
• FlyBaseID: FBgn0032341
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_061510228.1
• Gene: Reps / 3291672
• VectorBaseID: AGAMI1_011705
• Length: 1126
• Species: Anopheles gambiae
• Alignment Length: 1178
• Identity: 449/1178 - (38%)
• Similarity: 574/1178 - (48%)
• Gaps: 337/1178 - (28%)

  Fly     1 MDVSLTEPETRFYSELFQ-CCDVEKTGKVPMLKATELFRSADIANETVIEITGLAGIPSTALHIS 64
            || .|:|.|.|:|::||: |.:.:..||:|.||||.|||||::::|.:.:||.|||||.||||:|
Mosquito     1 MD-ELSEAELRYYNDLFKICSETDGAGKIPALKATSLFRSANLSSEIINKITALAGIPQTALHLS 64

  Fly    65 RTQFYSCLKLIAAHQAAMPLRQELILATFPLPLPHFSWKEAVTAP-------------------- 109
            |.|||.|||||||:|||:|||:|::..:..||||.|||.:..|.|
Mosquito    65 RQQFYGCLKLIAAYQAAVPLREEILTTSVNLPLPQFSWIDPATGPSSGAGDSSSLSSSILSAAGS 129

  Fly   110 ------------VAVENGLTALPPPPPTDRRNSLRR------------NSQQEQLQDT------S 144
                        ....||.:.:      :||.||:.            ::.|:....|      |
Mosquito   130 GSGTGAGGSQTGTLERNGYSEV------NRRASLKMAGSVAGGGGGAGSTTQDSSASTGGEMTNS 188

  Fly   145 DVPSTDSEVEQNESVDDATGHGRG---------TDGCGVVSSSSRENV----------GRRRGGG 190
            |.||||||||.|   ||.....||         ..|.|:|...:...:          |...|||
Mosquito   189 DQPSTDSEVEHN---DDPVNMIRGERERHTVGMLKGGGIVMIGNSHPLVGGGAGGGGHGGGHGGG 250

  Fly   191 TGGGSPEAWSTNSDSPTPTNSVAERPWAQDTLWQGLLGDEHRQLLGTEEESSDRHSSDDDDNESE 255
            .||||||||||.||||||||||||||||..||||||:.:|.|||||||||||||||||:|:.|.:
Mosquito   251 GGGGSPEAWSTASDSPTPTNSVAERPWANQTLWQGLVCEEQRQLLGTEEESSDRHSSDEDEQEID 315

  Fly   256 LVTIYQITPEQREYYNKQFRTVQRDPHGLLSGQAARNFFEKSRIPVEELRHIWQLCDVTRDGALS 320
            |...|||:..|::||.|||||:|.|.|||:||..||.||||||||::|||||||:|||||||||:
Mosquito   316 LEYFYQISQTQKDYYLKQFRTIQPDVHGLVSGPVARVFFEKSRIPIDELRHIWQMCDVTRDGALN 380

  Fly   321 LSEFTAAMHLVVLRRNNIPLPTSLPHCLHPNVLQ------------------AAAS--------G 359
            |:|||||||||||||||||:|.:||.||.|.:||                  |:||        |
Mosquito   381 LAEFTAAMHLVVLRRNNIPVPATLPPCLLPTLLQHSLLQPAAGGASGSSALPASASAEVPTTTGG 445

  Fly   360 SGQGVTSSSSAALPQ---EPPEADLLHLNDDDE---------DDHTD--------NTIIAGNLSG 404
            ||.|..:.::.:|..   ||.|||||||..||.         |.|.|        :|:....::.
Mosquito   446 SGSGAAAGANVSLANERTEPAEADLLHLESDDNVESSSRKRFDAHKDYQRMVPVPDTLTFAKVAA 510

  Fly   405 SSTTSKP-----------RPNVPSDKNIMNLSSISTSSQASNSSKREATPQNSLGKNRSISNS-- 456
            .:....|           .|:|.|...:.:.|..:.|...:|::|         |.:.|.|||
Mosquito   511 PAGGGAPVGVSVAAHDASPPSVSSATGVGSSSGTTGSVSVANATK---------GSSNSGSNSSS 566

  Fly   457 ------------PNVEKPV---------SGTVSSTASAVD--------STN-----VSSQWTKFS 487
                        |||..||         :|:......:.|        .||     .:.:||||.
Mosquito   567 AAVSTTGGRKTPPNVSPPVLAQHHQQHAAGSAQKVKQSADHPATPPNTKTNKEWNSTTKEWTKFM 631

  Fly   488 ESPTTSAVSVQSTTGAAPVVAAGAAASGASSPGLKPVLFDMKRSAQDVVSNPQILHPVPLRVTPI 552
            ||||                      |..||||.|||.||::|:.|.:||||.|:|||||||||:
Mosquito   632 ESPT----------------------SNVSSPGPKPVNFDLQRTTQAIVSNPHIVHPVPLRVTPV 674

  Fly   553 GTAIASSAE----SSNENESAVAQRED--SPKAISSTTVNNQSSAVVPGISGVAGSSHRDSSDLR 611
            |.....:..    |.......|.|..|  |||..:|.....|....:|........|..:|.|||
Mosquito   675 GAEAVDNGSLVYGSDGTGSLMVVQTRDDSSPKQQTSQQQQQQQQPPLPHHHSTPRDSLTNSGDLR 739

  Fly   612 AIQRPQAKKLPAKN-SALPPPPQREPSIGSTGPSESQE----------PQAAYVASSLAS----- 660
            ||||||.||.|:|. .|:||||||:.  |...|:.|..          ..:.:.|||.:|
Mosquito   740 AIQRPQPKKPPSKGVGAIPPPPQRDS--GGAHPASSAHSGNDSMTVSLDASGFAASSSSSAGGSN 802

  Fly   661 ------------KKE-------PPPLPPPRP--HRHARSSSLDLNKFKIGATGGAQQAEI----- 699
                        ||:       |||||||||  |||.|||||||||.|: .|..|..|.|
Mosquito   803 ATATIERLPSLAKKQSVDQQPPPPPLPPPRPSAHRHTRSSSLDLNKLKL-TTNSAAMAPIGDPLK 866

  Fly   700 -------------TAQA-SFDMQTSTGFADFTHF---ADEG--AANVVDEQQL------------ 733
                         |.:| :...|.:.||||||||   |..|  ..::.|...:
Mosquito   867 MPPPPEVPPRVTPTGEAPTGHRQPAHGFADFTHFPSGASSGQRIGSIGDSSNITTIHLDAAGNMT 931

  Fly   734 -HSLPPAAPPPQAAVVPPTRITLQQAQQRVSAFEVYRKP-----------QTPRGSQSPPQQPPP 786
             ||.|..     :..:|.   :|...|.|.|||||||||           ...||||||..|.||
Mosquito   932 HHSTPRG-----SGTLPK---SLVMHQPRNSAFEVYRKPHADGRLVAAAASAARGSQSPQSQQPP 988

  Fly   787 PAPAVGLTTQTGQLP-SAESFEKRVTAISDSLRHVSFKQGQAN-----TTEVLQRLREQNNSLLH 845
            ...:..:.|....|. ....::||::|:|||||.|.||   ||     ..:||::|:|||..||.
Mosquito   989 LVTSRSVDTSGAVLSGGGGDYDKRISALSDSLRQVRFK---ANDPPPVMPDVLKQLKEQNLLLLR 1050

  Fly   846 LCNDLSDELLSVQTRKEEMRLKLE---------GLNASDSTGRTSSSICAPVTANVTGGSS---- 897
            :|||||:|||.:|.::|::|:|:|         |...|:||..|..|         ||.||
Mosquito  1051 ICNDLSEELLHIQQKREDIRIKIELQEQILGGGGGGGSNSTTSTMLS---------TGPSSLPAV 1106

  Fly   898 GSAGAAYT 905
            .|..:::|
Mosquito  1107 SSTSSSHT 1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reps	NP_609487.2	EH	262..345	CDD:197477	61/82 (74%)
Reps	XP_061510228.1	None