Protein Alignment Reps and Reps1

DIOPT Version :10

• Sequence 1: NP_609487.2
• Gene: Reps / 34542
• FlyBaseID: FBgn0032341
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_038961086.1
• Gene: Reps1 / 292944
• RGDID: 1307131
• Length: 828
• Species: Rattus norvegicus
• Alignment Length: 997
• Identity: 260/997 - (26%)
• Similarity: 376/997 - (37%)
• Gaps: 311/997 - (31%)

  Fly     3 VSLTEPETRFYSELFQCCDVEKTGKVPML-KATELFRSADIANETVIEITGLAGIPSTAL-HISR 65
            ::|::.|.::||:||..||:|.|.||.:. :..||||:|.:.|:.|::|..|.|  :|.| :..|
  Rat     4 LTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCG--ATRLGYFGR 66

  Fly    66 TQFYSCLKLIAAHQAAMPLR------------------------QELILATF--------PLPLP 98
            :|||..|||:|..|:..|||                        :|.||:..        .||||
  Rat    67 SQFYIALKLVAVAQSGFPLRVESINTEMSAVKSMDIVWIFHKLFREEILSVLLFLWSTVKDLPLP 131

  Fly    99 HF-------SWKEAVTAPVAVENGLT---ALPPPPPTDRRNSLRRNSQQEQLQDTSDVPSTDSEV 153
            .|       ..:.|.:.....||...   .:||||...:......:....|.:.::|.....|.|
  Rat   132 RFVASKNEQESRHAASYSSDAENQSAYAGVIPPPPGRGQVKKAPGSHDAAQPRPSADQQEPASPV 196

  Fly   154 ---EQNESVDDAT--GHGRGTDGCGVVSSSSRENVG----------RRRGGGTG-----GGSP-- 196
               :|:......|  .|.|...|    .:|.|...|          .:.|...|     |.||
  Rat   197 VSPQQSPPTSPHTWRKHNRHPSG----GNSERPLAGPGPFWSPFGDAQSGSSAGDAVWSGHSPPP 257

  Fly   197 --EAWSTNSDSPTPTNSVAERPWA--QD-----TLWQGLLGDEHRQLLGTEEESSDRHSSDDDDN 252
              |.|.:.:|:| ||:::.....|  ||     |:......:|.|           |.||..||.
  Rat   258 PQENWVSFADTP-PTSALLTMHPASVQDQTTVRTVASATTANEIR-----------RQSSSYDDP 310

  Fly   253 ESELVTIYQITPEQREYYNKQFRTVQRDPHGLLSGQAARNFFEKSRIPVEELRHIWQLCDVTRDG 317
                   ::||.|||:||..||:|:|.|.:|.:.|.||:.||.||::|:.||.|||:|.|..:||
  Rat   311 -------WKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDG 368

  Fly   318 ALSLSEFTAAMHLVVLRRNNIPLPTSLPHCLHPNVLQAAASGSGQGVTSSSSAALPQEPPEADLL 382
            ||:|.||.||.||||.|:|...||..||..|.|.::..           ..||.:..:|.|...
  Rat   369 ALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLIDL-----------EDSADVGDQPGEVGY- 421

  Fly   383 HLNDDDEDDHTDNTIIAGNLSGSSTTSKPRPNVPSDKNIMNLSSISTSSQASNSSKREATPQNSL 447
                                          |..|:                      ||.|
  Rat   422 ------------------------------PGSPA----------------------EAPP---- 430

  Fly   448 GKNRSISNSPNVEKPVSGTVSSTASAVDSTNVSSQWTKFSESPTTSAVSVQSTTGAAPVVAAGAA 512
                  |.||::.     :::.|...::.:  |.||..|||..::|....|..:..||
  Rat   431 ------SKSPSMP-----SLNQTWPELNQS--SEQWETFSERSSSSQTLTQFDSNIAP------- 475

  Fly   513 ASGASSPGLKPVLFDMKRSAQDVVSNPQILHPVPLRVTP--IGTAIASSAESSNENESAVAQRED 575
                :.|                  :..|:||||:|:||  |.........||.::.:..:....
  Rat   476 ----ADP------------------DTAIVHPVPIRMTPSKIHMQEMELKRSSGDHTNPTSPLLV 518

  Fly   576 SPKAISSTTVNNQSSAVVPGISGVAGSSHRDSSDLRAIQRPQAKKLPAKNSALPPPPQREPSIGS 640
            .|..:|.....|.|.....|.:...|.|..||                    .|..|::   |||
  Rat   519 KPSDLSEENKINSSVKFPSGNTVADGYSSSDS--------------------FPSDPEQ---IGS 560

  Fly   641 TGPSESQEPQAAYVASSLASKKEPPPLPPPRPH-RHARSSSLDLNKFKIGATGGAQQAEIT---- 700
            .|..:...       |..:.....||.|||||. .|:||||||:|:....|||..|...:|
  Rat   561 NGARQRSH-------SGASPDNTAPPPPPPRPQPSHSRSSSLDMNRTFAVATGQQQAGVVTHPPA 618

  Fly   701 -------AQA------------SFDMQTST---------GFADFTHFADEGAANVVDEQ----QL 733
                   :||            .....|||         .||||:.|....|:||.:||    :.
  Rat   619 VPPRPQPSQAPGPSVHRPVDADGLITHTSTSPQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEK 683

  Fly   734 HSLPPAAPPPQAAVVPPTRITLQQAQQRVSAFEVYRKPQTPRGSQSPPQQPPPPA---------- 788
            |   |...|.:.|..|.:.:.:.||..::........|.......:|...||.|.
  Rat   684 H---PEVLPAEKASDPSSSLRVAQADSKIEEKTAAGVPANVSKGTTPLAPPPKPVRRRLKSEDEL 745

  Fly   789 -PAVGLTTQ-TGQL-------PS-AESFEKRVTAISDSLRHVSFKQGQANTTEVLQRLREQNNSL 843
             |.|...|| ||.|       || ..|..|...||..|:|    :..:.||  ||.||   |:.|
  Rat   746 RPDVDEHTQKTGVLAAVLASQPSIPRSVGKDKKAIQASIR----RNKETNT--VLARL---NSEL 801

  Fly   844 LHLCNDLSDELLSVQTRKEEMR 865
            .....|:.:|.:|::.:.|::|
  Rat   802 QQQLKDVLEERISLEVQLEQLR 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reps	NP_609487.2	EH	262..345	CDD:197477	45/82 (55%)
Reps1	XP_038961086.1	EH	6..85	CDD:197477	33/80 (41%)
		PRK07764	<163..260	CDD:236090	21/100 (21%)
		EH	310..401	CDD:197477	48/97 (49%)