Protein Alignment Reps and Reps1

DIOPT Version :10

• Sequence 1: NP_609487.2
• Gene: Reps / 34542
• FlyBaseID: FBgn0032341
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_033074.2
• Gene: Reps1 / 19707
• MGIID: 1196373
• Length: 795
• Species: Mus musculus
• Alignment Length: 966
• Identity: 259/966 - (26%)
• Similarity: 373/966 - (38%)
• Gaps: 282/966 - (29%)

  Fly     3 VSLTEPETRFYSELFQCCDVEKTGKVPML-KATELFRSADIANETVIEITGLAGIPSTAL-HISR 65
            ::|::.|.::||:||..||:|.|.||.:. :..||||:|.:.|:.|::|..|.|  :|.| :..|
Mouse     4 LTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCG--ATRLGYFGR 66

  Fly    66 TQFYSCLKLIAAHQAAMPLRQELILATFPLPLPHFSWKEAVTAPVAVENGLTA------------ 118
            :|||..|||:|..|:..|||.|.|.....||||.|     |.:....|:.|.|
Mouse    67 SQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRF-----VASKNEQESRLAASYSSDSENQGSY 126

  Fly   119 ---LPPPPPTDR-------RNSLRRNSQQEQLQDTSDV------PSTDSEVEQNESVDDATGHG- 166
               :||||...:       .::::.....||.:..|.|      |.|.....:..|...:.|:.
Mouse   127 SGVIPPPPGRGQVKKGPGSHDAVQPRPSAEQQEPVSPVVSPQQSPPTSPHTWRKHSRHPSGGNSE 191

  Fly   167 RGTDGCGVVSSSSRENVGRRRGGGTGGGSPEAWSTNSDSPTPTN--SVAERPWAQDTLWQGLLGD 229
            |...|.|...|.    .|..:.|.:.|.:  .||..|..|...|  |.|:.|.....|.......
Mouse   192 RPLTGPGPFWSP----FGDAQAGSSAGDA--VWSGQSPPPPQDNWVSFADTPPTSALLTMHPASV 250

  Fly   230 EHRQLLGTEEESSD-----RHSSDDDDNESELVTIYQITPEQREYYNKQFRTVQRDPHGLLSGQA 289
            :.:..:.|...::.     |.||..:|.       ::||.|||:||..||:|:|.|.:|.:.|.|
Mouse   251 QDQTTVRTVASAATANEIRRQSSSYEDP-------WKITDEQRQYYVNQFKTIQPDLNGFIPGSA 308

  Fly   290 ARNFFEKSRIPVEELRHIWQLCDVTRDGALSLSEFTAAMHLVVLRRNNIPLPTSLPHCLHPNVLQ 354
            |:.||.||::|:.||.|||:|.|..:||||:|.||.||.||||.|:|...||..||..|.|.::.
Mouse   309 AKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYDLPEKLPESLMPKLID 373

  Fly   355 AAASGSGQGVTSSSSAALPQEPPEADLLHLNDDDEDDHTDNTIIAGNLSGSSTTSKPRPNVPSDK 419
            .           ..||.:.::|.|.                     ..|||...:.|
Mouse   374 L-----------EDSADVGEQPGEV---------------------GYSGSPAEAPP-------- 398

  Fly   420 NIMNLSSISTSSQASNSSKREATPQNSLGKNRSISNSPNVEKPVSGTVSSTASAVDSTNVSSQWT 484
                      |...|..|..:..|:    .|:|                           |.||.
Mouse   399 ----------SKSPSMPSLNQTWPE----LNQS---------------------------SEQWE 422

  Fly   485 KFSESPTTSAVSVQSTTGAAPVVAAGAAASGASSPGLKPVLFDMKRSAQDVVSNPQILHPVPLRV 549
            .|||..::|....|..:..||           :.|                  :..|:||||:|:
Mouse   423 TFSERSSSSQTLTQFDSNIAP-----------ADP------------------DTAIVHPVPIRM 458

  Fly   550 TPIGTAIASSAESSNENESAVAQREDSPKAISSTTVNNQSSAVVPGISGVAGSSHRDSSDLRAIQ 614
            ||                |.:..:|...|..||...|..|..:|         ...|.|:...|.
Mouse   459 TP----------------SKIHMQEMELKRTSSDHTNPTSPLLV---------KPSDLSEENKIN 498

  Fly   615 RPQAKKLPAKNS--------ALPPPPQREPSIGSTGPSESQEPQAAYVASSLASKKEPPPLPPPR 671
              .:.|.|:.|:        :.|..|::   |||     |...|.::..:|..:...|||.|.|:
Mouse   499 --SSVKFPSGNTVDGYSSSDSFPSDPEQ---IGS-----SVTRQRSHSGTSPDNTAPPPPPPRPQ 553

  Fly   672 PHRHARSSSLDLNKFKIGATGGAQQAEITA------------QA------------SFDMQTST- 711
            | .|:||||||:|: ....|.|.|||.:.|            ||            .....|||
Mouse   554 P-SHSRSSSLDMNR-TFAVTTGQQQAGVVAHPPAVPPRPQPSQAPGPSVHRPVDADGLITHTSTS 616

  Fly   712 --------GFADFTHFADEGAANVVDEQ----QLHSLPPAAPPPQAAVVPPTRITLQQAQQRVSA 764
                    .||||:.|....|:||.:||    :.|   |...|.:.|..|.:.:...||..:...
Mouse   617 PQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEKH---PEVLPAEKASDPSSSLRAAQADSKAEE 678

  Fly   765 FEVYRKPQTPRGSQSPPQQPPPPA-----------PAVGLTTQ-TGQL-------PS-AESFEKR 809
            ......|.......:|...||.|.           |.|...|| ||.|       || ..|..|.
Mouse   679 KTATNVPANVSKGTTPLAPPPKPVRRRLKSEDELRPDVDEHTQKTGVLAAVLTSQPSIPRSVGKD 743

  Fly   810 VTAISDSLRHVSFKQGQANTTEVLQRLREQNNSLLHLCNDLSDELLSVQTRKEEMR 865
            ..||..|:|    :..:.||  ||.||   |:.|.....|:.:|.:|::.:.|::|
Mouse   744 KKAIQASIR----RNKETNT--VLARL---NSELQQQLKDVLEERISLEVQLEQLR 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reps	NP_609487.2	EH	262..345	CDD:197477	45/82 (55%)
Reps1	NP_033074.2	EH	6..85	CDD:197477	33/80 (41%)
		PRK07764	<99..228	CDD:236090	29/139 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..238		28/131 (21%)
		EH	278..369	CDD:197477	48/97 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..433		19/122 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	469..720		69/274 (25%)
		Interaction with RALBP1	651..795		40/152 (26%)