Protein Alignment Ge-1 and VCS

DIOPT Version :10

• Sequence 1: NP_609486.2
• Gene: Ge-1 / 34541
• FlyBaseID: FBgn0283682
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_187938.2
• Gene: VCS / 820530
• AraportID: AT3G13300
• Length: 1344
• Species: Arabidopsis thaliana
• Alignment Length: 1473
• Identity: 307/1473 - (20%)
• Similarity: 556/1473 - (37%)
• Gaps: 339/1473 - (23%)

  Fly    19 LSASSSPPPSVHRSPRCGKASTAYHP--------PPADACISITASAIDAASG-----MSNSAEQ 70
            :||..||.....:......|:|..||        ||    :::.:...:...|     :.|:...
plant    58 ISAQPSPVTQQQQDVSSSSAATNLHPQRTLSYPTPP----LNLQSPRSNHNPGTHILALLNNTNN 118

  Fly    71 DKPIAANGNAAEPQEIEVIHFQAQEKQ-----------CCRVIRSNKTKVLTSGGVHTRGSSKVK 124
            ..|:|   |.....::.|::.....:.           .|::.:..:..     |.|......|:
plant   119 GAPVA---NQEPSHQLPVVNHNEIARSFPGGSGPIRVPSCKLPKGRRLI-----GEHAVYDVDVR 175

  Fly   125 LKNIVDYKWE----RKYYYPGHLVAVHRDGKHLAYAINVNNKATGME-GMVRVCNIATSMRALIK 184
            |:..:..:.|    .||.....||.    |:.:  |:|......|:: |.:||.||.|::|:|.:
plant   176 LQGEIQPQLEVTPITKYGSDPQLVV----GRQI--AVNKVYICYGLKGGNIRVLNINTALRSLFR 234

  Fly   185 GMSGEVLDLQFAHTDCERILAVIDVSSLFVYKVD---------QIEGNLLCNL-VLKVEDPIANY 239
            |.|..|.|:.|...|.:.:.:|.....:||:|:.         ||.|.::..| :|..||
plant   235 GHSQRVTDMAFFAEDVDMLASVSLDGKVFVWKISEGSEGEDQPQITGKIVLALQILGEED----- 294

  Fly   240 VPEYDMVSW-CP----YVCSSSATVPINDDDDENQLLIWSRSSQFQCFQVKMIVSEHGRGKIQPA 299
             .::..|.| |.    .|.|....|...|.....:..::|..:..||...|:|      ..:|..
plant   295 -TKHPRVCWHCHKQEILVVSIGKHVLRIDTTKVGRGEVFSAEAPLQCPLDKLI------DGVQIV 352

  Fly   300 ALESGYLKIEEDSLITCAALSPDGTTVAAACADGLVRFYQIYLFDVRNHRCLHEWKPHDGKKVCS 364
            ....|    |...|..|..::   |.:.::..||.::.:|     .|..:.|...:||||..|.|
plant   353 GKHDG----EVTDLSMCQWMT---TRLVSSSVDGTIKIWQ-----DRKAQPLVVLRPHDGHPVSS 405

  Fly   365 LFFLDNINKPVEESYWQHV--ITTSDANTEIKLW------------NCSLWKCLQTINVVASPSS 415
            ..|:.:..:|      .|:  ||....|.|:|:|            :...|:|.||:::   .||
plant   406 ATFVTSPERP------DHIILITGGPLNREMKIWVSAGEEGWLLPADAESWRCTQTLDL---KSS 461

  Fly   416 LQPR------NFIAGIDRSANYLVLSCLDSLAVYVMQI--GSTGGADSENRSSDSEGEGCDTSKR 472
            .:||      |.:..:. .|..|:|:.....|:|.:.:  ||:                 ....|
plant   462 TEPRAEEAFFNQVIALS-EAGLLLLANAKRNALYAVHLDYGSS-----------------PVGTR 508

  Fly   473 IQNVAEFKLSSGILSFSIVNASMRRVKNSIESYYPIEEPDDFDDDSNSTSALVLHMFVVQAKSLQ 537
            :..::||.::..||||             |.:..|.|||             ::.::.||..::|
plant   509 MDYLSEFTVTMPILSF-------------IGTNDPPEEP-------------IVKVYCVQTLAIQ 547

  Fly   538 ECQIIYQPCVAEKTERSSL-NSKRSQTPEDNLLIKEEPESPNSG-------TVGAVQLDALFAKS 594
            :..:....|:....|...| .|..|.:.|.||:   |..|..||       :|.:|...::....
plant   548 QYTLDLCLCLPPPIENMGLEKSDSSVSREANLV---EGMSEPSGLKPTDLPSVDSVPKPSIIVNR 609

  Fly   595 AKRASTGSSSAMVAVAAAAAAAPSAILQDATKEA--AKSESPQLSSAYTQQVNLMTPDAFSASGT 657
            ::.|:             ..:.|||   :||.:|  ..:..|:.|.         .|...|.:|:
plant   610 SESAN-------------KLSFPSA---EATSQAIVPPNGEPKTSG---------LPSQTSGAGS 649

  Fly   658 AAAAAVFVSTSTTTSIGTDSSTTTSGQDRSIDSAVLQTIRMLATVTSKTSENPNAEVLLNLMNNT 722
            |.|      |.....:....|:..||....:::  ::.:.....:..||   |:|:..:
plant   650 AYA------TLPQLPLSPRLSSKLSGYHTPVEA--IEPVIPHHELGGKT---PSADYSV------ 697

  Fly   723 LIEDREQQKLKEK-LDARKKFIAIDRNPERNVA-ENLASGSSSPS------------REV----- 768
               ||:...:.|: ||. .....|.|:.:.||. ::..||..|||            .|:
plant   698 ---DRQMDAVGERNLDV-SSVEEISRSKDSNVTPDDDVSGMRSPSAFFKHPTHLVTPSEILMGVS 758

  Fly   769 -QEIMATQDDADAYEAELENLDDDDDDEEEELANSSPLPEAVDGTWPIVKLSSH----SAELQNA 828
             .|...|.:|....:|.::::::|..|.|.|:...|......:|     :::.|    :...:|.
plant   759 SAEASITTEDRRDRDANIQDVNNDPRDTEVEVKEISEARSTQNG-----EINDHDETENCTSENR 818

  Fly   829 AQIMSQAVQN------------TNNGNVP--------PTLGGGHNNNTSVGSNSNNNTATTLSTS 873
            .::....|.|            |....:|        |...|..:     |.:|....|..|...
plant   819 EKVFCSQVSNLSTEMARDCYPSTEGTFIPGESKAYGQPIKAGDES-----GVDSRGGPAKLLKGK 878

  Fly   874 NTSSSNNAGGTCVDSSGTGELNAKMELLIDLVKAQSKQI-NKLENEVNKLQKQQEAAAALHSKQD 937
            ...:.|:.|      .|....::.:..|.|....||:.: :.:.:.:.:|...||....:.:.|.
plant   879 KQKAKNSQG------PGLSSTSSNVANLADSFNEQSQSLSHPMTDLLPQLLAMQETMNQVMASQK 937

  Fly   938 TSLEPKNLSQLAYKIEMQLSKLMEQYLKRYENEHKKKLTEFLAARESQNRELRDSVLQVLNQYVM 1002
            ..  .:.||..|.....:.||.:|..|.|...:..|...:.|.||..:.....:..|:...|.::
plant   938 EM--QRQLSNAATGPIGKESKRLEVALGRMIEKSSKSNADALWARIQEETVKNEKALRDHAQQIV 1000

  Fly  1003 NHFTDIIGNVLNMELQRQLLPRVNANMDQLQAQMQVEIVQKL--SVFDKTVKENIAQVCKSKQFL 1065
            |..|:.:...||...::.:...: |.:....|:..|.:::|.  |...::.:..|..  |:...|
plant  1001 NATTNFMSKELNAMFEKTIKKEL-AAIGPALARSVVPVIEKTVSSAITESFQRGIGD--KAVNQL 1062

  Fly  1066 D---------TFGKSVLIGVQTS----LQTAFIESMSSTLIPAYEKSSQNMFKQLHDAFSVGIKD 1117
            |         |..:.:....|||    ||.....|:.|::||::||:.:.||.|:..||..||.:
plant  1063 DKSVNIKLEATVARQIQAQFQTSGKQALQEGLRSSVESSVIPSFEKACKAMFDQIDSAFQKGIAE 1127

  Fly  1118 FMVQFNTYLQHMPQPQAGSGNTEEINNKLSMLKQLVESSLHKHRTELTDAMLETQREVKSLEIL- 1181
            .        .:..|.:..||:::..:.    ||:.:.|:....:. |:..:.||||.:.:|...
plant  1128 H--------TNAAQQRFDSGHSQLAHT----LKESITSASSVAQA-LSRELAETQRNLLALAAAG 1179

  Fly  1182 --------LARQVQETIRAELRKHMEAQNVAMRSQAATPAPPYDLRDSIKQLLMAGQINKAFHQA 1238
                    |..|:.......|.:.:||              |.|....:.:|:...:..::|..|
plant  1180 ANSGGSNSLVTQLSGGPLGALLEKVEA--------------PMDPTTELSRLISERKYEESFTSA 1230

  Fly  1239 LLANDLGLVEFTLRHTDSNQAFAPEGCRLEQKVLLSLIQQISADMTNHNELKQRYLNEALLAINM 1303
            |..:|:.:|.:.....|.....|.....|.|.|||||:||::.|::.....|..::.:.:.|||.
plant  1231 LQRSDVSIVSWLCSQVDLRGLLAMNPLPLSQGVLLSLLQQLACDISKDTSRKLAWMTDVVAAINP 1295

  Fly  1304 ADPITREHAPKVLTELYRNCQQFIKNSPKNSQFSNVRLLMKAI 1346
            :|.:...||..:..::|:..... :|:| .|..|.:||:|..|
plant  1296 SDQMIAVHARPIFEQVYQILHHH-RNAP-GSDVSAIRLIMHVI 1336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ge-1	NP_609486.2	Ge1_WD40	119..452	CDD:465162	90/374 (24%)
		WD40 repeat	144..185	CDD:293791	13/41 (32%)
		WD40 repeat	191..230	CDD:293791	11/48 (23%)
		WD40 repeat	235..307	CDD:293791	14/76 (18%)
		WD40 repeat	315..355	CDD:293791	7/39 (18%)
		WD40 repeat	362..408	CDD:293791	15/59 (25%)
		Mplasa_alph_rch	893..>1063	CDD:275316	33/172 (19%)
VCS	NP_187938.2	Ge1_WD40	183..498	CDD:465162	86/354 (24%)
		WD40 repeat	240..281	CDD:293791	10/40 (25%)
		WD40 repeat	290..354	CDD:293791	16/75 (21%)
		WD40 repeat	359..396	CDD:293791	8/44 (18%)
		WD40 repeat	404..457	CDD:293791	14/58 (24%)