DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG16854 and CG15695

DIOPT Version :9

Sequence 1:	NP_001245974.1	Gene:	CG16854 / 34539	FlyBaseID:	FBgn0032338	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster

Alignment Length:	630	Identity:	188/630 - (29%)
Similarity:	308/630 - (48%)	Gaps:	87/630 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 YFVDTTGCRMPHFEVSDDTIAQFIFKPRPY-SCNRALIRTSDTIPGQLHLNLEASELLAYYNISD 164
            |||.:..|:|.|.....:.| |.|:|...| .|:::  |...|:               .||::|
  Fly   156 YFVHSPQCQMSHPNPFANNI-QHIYKKHSYIVCDKS--RDMITV---------------NYNVTD 202

  Fly   165 LS-------SVNCNYTEVKRKTDSSNTH-----SPAVSFKLDKVMKLPLSSEFICMWC-YDSLDK 216
            .:       :..|.:.::.|...|:|..     .|.|.|..|.::...:|:  :..:| ....||
  Fly   203 STYRLHKNENSTCCFKQILRAGTSANADHKYKLGPCVEFHQDFLVPTEVSA--MITYCRRPPFDK 265

  Fly   217 LFYKDCHFFAVDKPRIRPPLKTGTDRVSFNKSKEEQERLSVMILGMDSLSHLNFLRQMRRTANYV 281
            :..||.  |:...||        .|::. |.:...:.|.||::.|:||:|.:|....|.|...|:
  Fly   266 VSQKDA--FSFVHPR--------KDQIE-NPTTPHRRRPSVLLWGIDSISRMNLELTMPRMYEYL 319

  Fly   282 RKHLSH-VEFWGYNKVGDNTFPNLVPLLSGLDDQELNLACTPKTLRSYDRCSFIWKRYQQLGYRS 345
            ..  .| .|..||||:||||||||:.:|:|.:....|..|.|:.:|..|.|.||||.::..||.:
  Fly   320 NN--QHWFELQGYNKMGDNTFPNLMAVLTGFNKTYANARCHPEKVRGLDACPFIWKDFKDKGYTT 382

  Fly   346 IFAEDVAMLSAFNYNQNGFRKQPTDYYLRPMIMEMEKTVAFKKDLNMHLCMGSRRTADVLLEYMK 410
            .||||.:..|.|:|:..||...|||.|.||:::.:||.:...:...|..|:|.:..::.:.:...
  Fly   383 AFAEDWSKFSTFDYSSRGFFNPPTDVYGRPLVLAVEKELTILQRGQMPYCLGRKPASEYIYDMGV 447

  Fly   411 KLVPRMSRDLYFSFFWTVALTHDYFNFPSLLDEAMLQQLMQLQDSGLLNRTVVMLLSDHGLRWGS 475
            :.........:|..|||...:|:.|:.||.:||.|::.:..|..:|:::.|:::..||||.|:|.
  Fly   448 QFTMVNRNSTFFGMFWTNTFSHNDFSMPSAMDERMVKYMRTLDKNGIMDNTIIIFFSDHGSRFGP 512

  Fly   476 FRRTYQGMMEERQPLMMLLYPPWMTERYPEAIANLRLNARRLTTPFDVHATMLQLLNLHNLEADQ 540
            .|....|.:|||.|.:.:..|.|:.|:||:.:.||::|..|||:|:|:|||:..:|
  Fly   513 LRNLDSGFVEERLPFIYIRVPRWIREKYPKLLRNLQMNKNRLTSPYDIHATLRHIL--------- 568

  Fly   541 LQRRSTEMDEPDSTLPR--GI----SLFLPIPAARTCEQAGIAAHWCTCHQRQELQTNDPRVQRA 599
                  |:|.|...|||  |.    |:|..:..:|.|.||||..|||.|:...::.|.||..:..
  Fly   569 ------ELDTPKDKLPRPDGCSSCHSVFEEVDWSRNCSQAGIEDHWCACNSFSDVPTTDPSARSM 627

  Fly   600 ARYLVRLINNRL---KDSSQCRTLYLNSILQALIAAPHSKIVKNISTDYAVDITLRLQTKPGLGV 661
            :..||..||..:   |.:.:|..|.||.|         |.:.:..:::..:   ::|..:||..:
  Fly   628 STQLVEAINEYVASKKGTKRCSRLKLNRI---------SSVQRRGNSNRYL---IQLMAQPGDAL 680

  Fly   662 FESTVRMTGYTTVLTG---TISRLNLYGSQSYCLNDPALKMFCYC 703
            ||:||........:..   :||||:.|.::|.|.:....|.:|.|
  Fly   681 FEATVDWDASAQRIPAQMPSISRLDTYAAKSRCSSVKETKKYCIC 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16854	NP_001245974.1	DUF229	126..626	CDD:281053	160/523 (31%)
CG16854	NP_001245974.1	ALP_like	255..533	CDD:293745	101/278 (36%)
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	160/522 (31%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	102/294 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JJT
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4742
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850