DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Samuel and Gmeb2

DIOPT Version :9

Sequence 1:	NP_001260372.1	Gene:	Samuel / 34530	FlyBaseID:	FBgn0032330	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_113991.2	Gene:	Gmeb2 / 83635	RGDID:	620481	Length:	530	Species:	Rattus norvegicus

Alignment Length:	406	Identity:	86/406 - (21%)
Similarity:	137/406 - (33%)	Gaps:	133/406 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   558 SPFMTNFLPFSSGIFPPLIDMSSTQALLTLA--------------------RAVKDA-------- 594
            ||..|.::|.:    |...|::.:.|.:|:.                    |.:|||
  Rat   191 SPTSTEYIPLT----PAAADVNGSPATITIETCEDPGDWTTTIGDDTFAFWRGLKDAGLLDEVIQ 251

  Fly   595 ----EIQEILRSKQQRSGSNASSPSASAAGTPRSSSTLNAALHQAAQF-VTPALIYSAQLQQQQ- 653
                |::|.::..|||    ...|....    |.:..||..:...... :...::.|.:.|..:
  Rat   252 EFQQELEETMKGLQQR----VQDPPLQL----RDAVLLNNIVQNFGMLDLVKKVLASHKCQMDRS 308

  Fly   654 -----------QQQQQQHQRQQQQ---QSQHASRQSSPRSTNDSTTVAPIGDGGGGSSIASAAPL 704
                       :||..:|:|:.::   :|||.|        |...|:.|:
  Rat   309 REQYARDLAALEQQCDEHRRRAKELKHKSQHLS--------NVLMTLTPV--------------- 350

  Fly   705 DLSSQPPAAKRFKAERRASSTATTATTATTGSSTSTPSP-PPLEQHDDINSGNANATL-GTRSGT 767
               |.|...||.:..|..|..|..|:...|.|:.....| .|:.|...:..|...:|| .|..|.
  Rat   351 ---SLPSPMKRPRLARATSGPAAMASQVLTQSAQIALGPGMPMSQLTSVPLGKVVSTLPSTVLGK 412

  Fly   768 GTGESSAAGSGAGVAKARRRCQAQSEEVNSWSVDDVCGFVGGIDICAEYVQSFRDQSIDGTGLPL 832
            |:.:::.|.|.|.                        ..:||..:.|.          .|:..|.
  Rat   413 GSPQAAPASSPAS------------------------PLLGGYTVLAS----------SGSTFPS 443

  Fly   833 LTEDH-------LVNSLGMKLG-PALKLRSIL-AKKLGGPCPCVACVAQAQQM-LALQTGGAAAA 887
            ..|.|       ::::..|:.| ..||:.|.| ...|.|..|.:..||||... ..:.|...|||
  Rat   444 TVEIHPDTSSLTVLSTAAMQDGSTVLKVVSPLQLLTLPGLGPTLQNVAQASPAGSTIVTMPTAAA 508

  Fly   888 TGATAGAGTV-TGAVA 902
            ||......|: ..|||
  Rat   509 TGPEEHTATIEVAAVA 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Samuel	NP_001260372.1	SAM_Samd7,11	795..862	CDD:188978	14/75 (19%)
Samuel	NP_001260372.1	SAM	795..852	CDD:197735	10/64 (16%)
Gmeb2	NP_113991.2	SAND	90..163	CDD:128554
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900