DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Samuel and sp100.3

DIOPT Version :9

Sequence 1:	NP_001260372.1	Gene:	Samuel / 34530	FlyBaseID:	FBgn0032330	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	XP_021329292.1	Gene:	sp100.3 / 555649	ZFINID:	ZDB-GENE-130530-997	Length:	599	Species:	Danio rerio

Alignment Length:	236	Identity:	45/236 - (19%)
Similarity:	82/236 - (34%)	Gaps:	65/236 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 TTASTATKRKHLERLASDLRQLGKKG-----RRSRSVSPCS--RYPAVAETARMLSERSLLLSGY 113
            |....:.:|..:|.|..:..|..|.|     |..||..|.|  :.|:.:...:...||..:||.|
Zfish   110 TVTKFSEERIGIETLTENSGQKEKNGTYNRKRNDRSDDPGSSAKKPSFSPHEKGSKERIWMLSRY 174

  Fly   114 -----------------GAIESSAKKLSEAATGGAGGGGGGAAGQAATPTTSQLSAPASSASSSS 161
                             ..:....|.:.|           ||.|:..:|:..:..|...|:.:..
Zfish   175 KTQLPVKCGDKEGILYRDKLAKGEKCIRE-----------GAQGRWFSPSEFEKFAGKESSRNWK 228

  Fly   162 MSSSSAGSTCTTNANTASVAAAYAAFYLEKVKHEKMDNHKDAP------MVTIHNNNNNNTINNN 220
            .|....|:.                  |:|:..|   ||...|      ..::..:..|.:|:::
Zfish   229 ASIRCDGTP------------------LKKLIEE---NHLQCPPMKNRDRTSVRKSKKNISISSS 272

  Fly   221 NSSSSSSSSIINNHQSSQPSLGHSVKRERLSPGSNSSSHNG 261
            .|||:.|.:..::.:.|:   ...|:::....|..|...:|
Zfish   273 ESSSTDSETSASSEEESE---AEDVQKQSKRAGLRSQFRSG 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Samuel	NP_001260372.1	SAM_Samd7,11	795..862	CDD:188978
Samuel	NP_001260372.1	SAM	795..852	CDD:197735
sp100.3	XP_021329292.1	HSR	12..108	CDD:308673
		SAND	178..247	CDD:307487	14/100 (14%)
		SAND	327..401	CDD:307487
		PHD_TIF1_like	428..471	CDD:277016
		Bromodomain	499..598	CDD:321986
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4333
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900