DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Samuel and Deaf1

DIOPT Version :9

Sequence 1:	NP_001260372.1	Gene:	Samuel / 34530	FlyBaseID:	FBgn0032330	Length:	968	Species:	Drosophila melanogaster
Sequence 2:	NP_001262069.1	Gene:	Deaf1 / 40164	FlyBaseID:	FBgn0013799	Length:	576	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	101/491 - (20%)
Similarity:	148/491 - (30%)	Gaps:	206/491 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 RKHLERLASDL------------------RQLGKKGRRSRSVSPCSRYPAVAETARMLSERSLLL 110
            ||.|..||.|:                  .||..|                   .||::..|...
  Fly    14 RKDLAALAEDVVKEEVILESSSHHHHHHHHQLDTK-------------------VRMVTSSSNDN 59

  Fly   111 SGYGAIESSAKKLSEAATGGAGGGGGGAAGQAATPTTSQLSAPASSASSSSMSSSSAGSTCTTNA 175
            ||.|.        :...|.|||||.|| .|..:.|    :|.|..|..:.:          |.|.
  Fly    60 SGSGG--------ASGGTSGAGGGNGG-GGVVSVP----VSLPIGSMITGT----------TFNV 101

  Fly   176 NTASVAAAYAAFYLEKVKHEKMDNHKDAPMVTIHNN-----------NNNNTI------------ 217
            .|..          :...|.|       ||:.:.||           |:..||
  Fly   102 ITPD----------QLPPHFK-------PMLCVDNNGYLSGSTVSMGNDLKTIVIQQQQTQPGGG 149

  Fly   218 ----NNNNSSSSSSSSIINNHQSSQPSLGHSVKRERLSPGSNSSSHNGELTVSSFARSRSATPSS 278
                ||..::::::::|..||..|               ||| :||:      |.|....|...:
  Fly   150 GGGANNAGTNTTATNTIGLNHDGS---------------GSN-NSHD------SLATLEHAAGGA 192

  Fly   279 SSYRGAGGGAGGGVS-----PSHQQQQQQQ--------------------QQSLQQQQRLSPPS- 317
            |...|.|||.|||.|     ||.|..:..|                    .:.::.:.:...||
  Fly   193 SGVGGGGGGTGGGSSGWSENPSTQHNEVFQIRCKTTCAELYRSKLGSGGRGRCVKYKDKWHTPSE 257

  Fly   318 --------------------GPSM------ATAT---TTSSLSSSSSASASASASASAATHMPLH 353
                                |.|:      .|.|   |..|.:......|..|||.......|..
  Fly   258 FEHVCGRGSSKDWKRSIKYGGKSLQSLIDEGTLTPHATNCSCTVCCDDEAGESASGPVRLFTPYK 322

  Fly   354 NLSTNLLNSIQQAAASQQQLRSSNSNSSSNISGSSNNTKSDGGAASNATDFSTRNYSDIMRCLAA 418
            ....|..:...::...    |..|::.|:|.:.::||..:.|..|:|..        |:...:||
  Fly   323 RRKRNQTDLDMESGPK----RKRNTHHSNNNNSNTNNNNTSGSGANNCV--------DVTAAVAA 375

  Fly   419 ------KYNNANPNDNNATRR-------NSYYDGST 441
                  ..||...::.|.|.:       |...|.||
  Fly   376 ATASVVDENNMFLSEENITSKDEPWAALNDSLDTST 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Samuel	NP_001260372.1	SAM_Samd7,11	795..862	CDD:188978
Samuel	NP_001260372.1	SAM	795..852	CDD:197735
Deaf1	NP_001262069.1	SAND	219..291	CDD:128554	6/71 (8%)
Deaf1	NP_001262069.1	zf-MYND	521..557	CDD:280009
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4333
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900