Protein Alignment dUTPase and DUT

DIOPT Version :10

• Sequence 1: NP_609479.1
• Gene: dUTPase / 34529
• FlyBaseID: FBgn0250837
• Length: 188
• Species: Drosophila melanogaster
• Sequence 2: NP_001020419.1
• Gene: DUT / 1854
• HGNCID: 3078
• Length: 252
• Species: Homo sapiens
• Alignment Length: 147
• Identity: 96/147 - (65%)
• Similarity: 114/147 - (77%)
• Gaps: 0/147 - (0%)

  Fly    12 AKKMKIDTCVLRFAKLTENALEPVRGSAKAAGVDLRSAYDVVVPARGKAIVKTDLQVQVPEGSYG 76
            |:..::....||||:|:|:|..|.||||:|||.||.||||..:|...||:||||:|:.:|.|.||
Human   104 ARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYG 168

  Fly    77 RVAPRSGLAVKNFIDVGAGVVDEDYRGNLGVVLFNHSDVDFEVKHGDRIAQFICERIFYPQLVMV 141
            |||||||||.|:||||||||:|||||||:||||||.....||||.||||||.||||||||::..|
Human   169 RVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEV 233

  Fly   142 DKLEDTERGEAGFGSTG 158
            ..|:|||||..||||||
Human   234 QALDDTERGSGGFGSTG 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dUTPase	NP_609479.1	trimeric_dUTPase	10..159	CDD:444938	96/147 (65%)
DUT	NP_001020419.1	PRK12727	17..>163	CDD:237182	30/58 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..104		96/147 (65%)
		dut	114..251	CDD:273149	95/137 (69%)