DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art8 and Prmt3

DIOPT Version :9

Sequence 1:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_598501.1	Gene:	Prmt3 / 71974	MGIID:	1919224	Length:	528	Species:	Mus musculus

Alignment Length:	335	Identity:	125/335 - (37%)
Similarity:	182/335 - (54%)	Gaps:	48/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLVYAV 69
            ||..|.:..|||.||||:.|.|:|.:.|..|..:||||:|:|||.||||||.|.||.||:.|.||
Mouse   217 YFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKVGAKKVIAV 281

  Fly    70 EASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLL 134
            :.|.:..: |:|:|..|.|.:.:.:|:.::||..||  .||||:|:|||||::||.|.||||||.
Mouse   282 DQSEILYQ-AMDIIRLNKLEDTIVLIKGKIEEVSLP--VEKVDVIISEWMGYFLLFESMLDSVLY 343

  Fly   135 ARDKFLKEGGLLFPSECTIFVAPCSVPSLFDD----WHNVDGIKMDTFARKLRTQKSSRPE-ITQ 194
            |:.|:|.:||.::|..|||.:...|..|...|    |.:|.|..|...      :|:..|| :.:
Mouse   344 AKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCM------KKAVIPEAVVE 402

  Fly   195 L--------NPQDLLHEGVVFHWMNLLDVE-ASDLDSIQFKEVITAQKAGNHQGFCIWFDVQFP- 249
            :        :|.|:.|  :..|..::.|:| :||......|..:....||       :||:.|.
Mouse   403 VVDHKTLISDPCDIKH--IDCHTTSISDLEFSSDFTLRTTKTAMCTAVAG-------YFDIYFEK 458

  Fly   250 --GEDFVLSTSPLSPPTHWKQCVVVL----PEESCENLEEKSPIAFQITMKRSAADMRKYNLEVD 308
              ....|.||.|.|..|||||.|.:|    |.::.|.|:.|      ||:.::..|.|  :|.|.
Mouse   459 NCHNRVVFSTGPQSTKTHWKQTVFLLEKPFPVKAGEALKGK------ITVHKNKKDPR--SLIVT 515

  Fly   309 L-LDPNTEEH 317
            | |:.:|:.:
Mouse   516 LTLNSSTQTY 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	SmtA	1..244	CDD:223574	97/252 (38%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607	56/106 (53%)
Prmt3	NP_598501.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		zf-C2H2_2	48..>97	CDD:289522
		AdoMet_MTases	256..356	CDD:100107	53/102 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820