DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art8 and Carm1

DIOPT Version :9

Sequence 1:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_067506.2	Gene:	Carm1 / 59035	MGIID:	1913208	Length:	608	Species:	Mus musculus

Alignment Length:	361	Identity:	126/361 - (34%)
Similarity:	178/361 - (49%)	Gaps:	58/361 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLVYAV 69
            ||..|..|...:.|::|..|...|..|||.|...||||||:|||.|:||||.|.|:||||.:|||
Mouse   150 YFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAV 214

  Fly    70 EASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLL 134
            |||.:|....: |::.|.||:.:.||..:|||..||   |:||||:||.||:.|.:|.||:|.|.
Mouse   215 EASTMAQHAEV-LVKSNNLTDRIVVIPGKVEEVSLP---EQVDIIISEPMGYMLFNERMLESYLH 275

  Fly   135 ARDKFLKEGGLLFPSECTIFVAPCSVPSLFDD-------W-----HNVD-----GIKMDTFARKL 182
            |: |:||..|.:||:...:.:||.:...|:.:       |     |.||     |..:|.:.|
Mouse   276 AK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFR-- 337

  Fly   183 RTQKSSRPEITQLNPQDLLHEGVVFHWMNLLDVEASDLDSIQFKEVITAQKAGNHQGFCIWFDVQ 247
                  :|.:...:.:.|:.:.|.: .:|.|:.:..||..|:.........:|...|...||||.
Mouse   338 ------QPVVDTFDIRILMAKSVKY-TVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVA 395

  Fly   248 FPGEDFV--LSTSPLSPPTHWKQ--CVVVLP--EESCENLEEKSPIAFQITMKRSAADM------ 300
            |.|....  |||:|..|.|||.|  |:...|  .::.:.|   |.....|..||.:.|:
Mouse   396 FIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL---SGTCLLIANKRQSYDISIVAQV 457

  Fly   301 -----RKYNLEVDLLDP-----NTEEHPVPCSCHMT 326
                 :..|| :||.:|     .|...|.|.| |.|
Mouse   458 DQTGSKSSNL-LDLKNPFFRYTGTTPSPPPGS-HYT 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	SmtA	1..244	CDD:223574	92/255 (36%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607	57/106 (54%)
Carm1	NP_067506.2	CARM1	35..139	CDD:402914
		AdoMet_MTases	189..284	CDD:100107	52/99 (53%)
		Transactivation domain	500..608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820