DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art8 and TRMT9B

DIOPT Version :9

Sequence 1:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_011542898.1	Gene:	TRMT9B / 57604	HGNCID:	26725	Length:	539	Species:	Homo sapiens

Alignment Length:	167	Identity:	35/167 - (20%)
Similarity:	60/167 - (35%)	Gaps:	46/167 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 FARKLRTQKSSRPEITQLNP--------------QDLLHEGVVFHWMNLLDVEASDLDSIQFKEV 228
            |:|.| .:.:.|.:|.::.|              |...|..:.|........:...||...|.|.
Human   337 FSRSL-DESTLRKQIERVRPLKNTEVWASSTVTVQPSRHSSLDFDHQEPFSTKGQSLDEEVFVES 400

  Fly   229 ITAQKA-------------GNHQGFCIWFDVQFPGEDFVLSTSPLSPPTHWKQCVVVLPEESCEN 280
            .:.:..             |:|||..    .:..|.:|:.||:.      ...||      ...|
Human   401 SSGKHLEWLRAPGTLKHLNGDHQGEM----RRNGGGNFLDSTNT------GVNCV------DAGN 449

  Fly   281 LEEKSPIAFQITMKRSAADMRKYNLE--VDLLDPNTE 315
            :|:.:|.|.:|..:.||.|...:|.:  :.:.||.|:
Human   450 IEDDNPSASKILRRISAVDSTDFNPDDTMSVEDPQTD 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	SmtA	1..244	CDD:223574	17/92 (18%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607
TRMT9B	XP_011542898.1	AdoMet_MTases	86..>224	CDD:302624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900