DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art8 and prmt9

DIOPT Version :9

Sequence 1:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001124239.1	Gene:	prmt9 / 553290	ZFINID:	ZDB-GENE-080728-4	Length:	859	Species:	Danio rerio

Alignment Length:	373	Identity:	86/373 - (23%)
Similarity:	148/373 - (39%)	Gaps:	84/373 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 HELMLKDRPRQEAYYNAILGNKDLFKDKI------VMDVGAGTGILSAFCAK-AGARLVYAVEAS 72
            |.|||.|..|...|..||       |..:      |:|:|.||||| ..||| |||..|||.|.|
Zfish   156 HFLMLNDHGRNHKYQLAI-------KKAVEGGCSSVLDIGTGTGIL-GMCAKMAGAAEVYACELS 212

  Fly    73 NVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAE-AEKVDIIVSEWMGFYLLHEGMLDSVLLAR 136
            ....::|.:::..||:.:.:|::..:..:..:|.: ..:|.::|:|.:...|..||::::::.|.
Zfish   213 KTMYELACEVLSANGMADCIKILHRKSLDMEIPKDIPNRVSLVVTETVDAGLFGEGIIETLIHAW 277

  Fly   137 DKFL-------------KEGGLLFPSECTIFVAPCSVPSLFDDWH----NVDGIKMDTFAR---- 180
            ...|             .:.|.:.|:..|:|......|.:.....    :|.|:.:....:
Zfish   278 KHLLLPPPNPGELLSSPSQTGRVIPAGATVFGVAVQCPEIRRHHRLCVSSVGGLDLSAVGQIYSP 342

  Fly   181 ---KLRTQKSSRPEITQLNPQDLLHEGVV--FHWMNLLDVE---ASDLDSIQFKEVI----TAQK 233
               ...|:.|:.|..|:...:  |..|.:  ......||::   ..:|:.:..:||:    ...:
Zfish   343 VSCLADTEDSTEPYTTERLSR--LRGGYIQLTQPFTALDIDFNNVQELEGLCSREVVQLCLCVTQ 405

  Fly   234 AGNHQGFCIWFDVQFPGEDFVLSTSPLSPPTHWKQCVV--------------VLPEESCEN---- 280
            .|......:||.:.. .:|..|||.| ...|.|:|.:.              :|.|.||::
Zfish   406 DGILDALAVWFQLHL-DQDNHLSTGP-QEETCWEQAIYPVQSTFNSVKRGDEILVEVSCKDSYLR 468

  Fly   281 ------LEEKSPIAFQITMKRSAADMRKYNLEVDL------LDPNTEE 316
                  :.:.:.|......| .|......|.||||      |..|.|:
Zfish   469 LCCVAIIRDGNTIHMDSATK-GAPKSLPANPEVDLCSALAGLQTNQEK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	SmtA	1..244	CDD:223574	61/269 (23%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607	34/127 (27%)
prmt9	NP_001124239.1	TPR_11	72..135	CDD:290150
		TPR repeat	72..98	CDD:276809
		MAS20	<96..133	CDD:295844
		TPR repeat	103..133	CDD:276809
		AdoMet_MTases	151..>267	CDD:302624	38/118 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810