DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art8 and prmt3

DIOPT Version :9

Sequence 1:	NP_609478.1	Gene:	Art8 / 34528	FlyBaseID:	FBgn0032329	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001017655.1	Gene:	prmt3 / 550348	ZFINID:	ZDB-GENE-041105-1	Length:	512	Species:	Danio rerio

Alignment Length:	319	Identity:	122/319 - (38%)
Similarity:	177/319 - (55%)	Gaps:	47/319 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YFDEYENLEIHELMLKDRPRQEAYYNAILGNKDLFKDKIVMDVGAGTGILSAFCAKAGARLVYAV 69
            ||..|.:..|||.||||:.|.|:|.:.:..|.|:||||:|:|||.||||||.|.|||||:.|.||
Zfish   201 YFSSYGHYSIHEEMLKDKVRTESYRDFMYRNMDVFKDKVVLDVGCGTGILSMFAAKAGAKKVVAV 265

  Fly    70 EASNVATKVALDLIEDNGLTNVVKVIQSRVEEFVLPAEAEKVDIIVSEWMGFYLLHEGMLDSVLL 134
            :.|.:..: |:|::..|.|.:.:.:|:.|:||..||  .||||||:|||||::||...||||||.
Zfish   266 DQSEIIYQ-AMDIVRSNNLEDTITLIKGRIEEIDLP--VEKVDIIISEWMGYFLLFGSMLDSVLY 327

  Fly   135 ARDKFLKEGGLLFPSECTIFVAPCSVPSLFDD----WHNVDGIKMDTFARKLRTQKSSRPE--IT 193
            |||::|.:.||:||..|:|.:|........:|    |.:|.|.||...      :|:..||  :.
Zfish   328 ARDRYLADDGLVFPDRCSISLAAVGDTQKHNDRIAFWEDVYGFKMTCM------KKAVIPEAVVE 386

  Fly   194 QLNPQDLLHEGVVFHWMNLLDVEASDLD-SIQFKEVITAQKAGNHQGFCI----WFDVQFP---G 250
            .|.|:.::.|..|...::...|..|:|: |:.|...|||      ..||.    :||:.|.   |
Zfish   387 VLKPETVISESAVIKTIDCGSVSVSELEFSVDFILKITA------SSFCTAIVGYFDIFFHKSCG 445

  Fly   251 EDFVLSTSPLSPPTHWKQCVVVLPEESCENLEEKSPIAFQ--------ITMKRSAADMR 301
            ...:.||:|....|||||.|.:|          :||:|.:        |:::::..|.|
Zfish   446 NKVMFSTAPNCTKTHWKQTVFLL----------ESPVAVKAGEDLPGHISVRKNRKDPR 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art8	NP_609478.1	SmtA	1..244	CDD:223574	102/249 (41%)
Art8	NP_609478.1	Methyltransf_18	40..147	CDD:289607	58/106 (55%)
prmt3	NP_001017655.1	zf-C2H2_2	39..>86	CDD:289522
prmt3	NP_001017655.1	Methyltransf_18	236..340	CDD:289607	58/106 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820